Factors influencing breast cancer risk
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Questions and Answers

What is the primary indication for ductography?

  • Resolving equivocal mammographic findings
  • Defining cystic masses
  • Nipple discharge, particularly with blood (correct)
  • Yearly mammogram

Which method is second only to mammography in frequency of use for breast imaging?

  • Ultrasound (correct)
  • Radiography
  • MRI
  • PET scan

How often should breast examinations be performed starting at age 40 according to the text?

  • Twice a year
  • Every 6 months
  • Every 2 years
  • Yearly (correct)

What do intraductal papillomas appear as in ductography?

<p>Small filling defects surrounded by contrast media (A)</p> Signup and view all the answers

What type of cancer shows as irregular masses or multiple intraluminal filling defects in ductography?

<p>Invasive ductal carcinoma (D)</p> Signup and view all the answers

What is the benefit of mammography screening mentioned in the text?

<p>50% reduction in stage II, III, and IV cancer (C)</p> Signup and view all the answers

What is the leading cause of death from cancer for women aged 20 to 59 years?

<p>Breast cancer (D)</p> Signup and view all the answers

What is the most common site-specific cancer in women?

<p>Breast cancer (B)</p> Signup and view all the answers

Which factor increases the risk of breast cancer by increasing serum estrogen levels?

<p>Alcohol consumption (A)</p> Signup and view all the answers

What was the leading cause of cancer-related mortality in women until it was surpassed by lung cancer in 1987?

<p>Breast cancer (C)</p> Signup and view all the answers

What can contribute to an increased risk of breast cancer by increasing serum estrogen levels?

<p>Long-term consumption of high-fat foods (A)</p> Signup and view all the answers

Which group has a very high incidence of breast cancer due to somatic mutations induced by radiation exposure?

<p>Survivors of atomic bomb blasts in Japan (A)</p> Signup and view all the answers

What is the probability of diagnosing breast cancer by MRI when both mammography and physical examination yield negative findings?

<p>Extremely low (D)</p> Signup and view all the answers

In what situation is MRI screening of the breasts gaining interest?

<p>For high-risk women and those with newly diagnosed breast cancer (D)</p> Signup and view all the answers

What percentage of women with a known breast cancer have been shown to develop contralateral breast cancer through MRI studies?

<p>5.7% (B)</p> Signup and view all the answers

Which method combination achieves almost 100% accuracy in diagnosing breast cancer?

<p>Diagnostic mammography, ultrasound, and stereotactic localization with FNA biopsy (D)</p> Signup and view all the answers

When are ultrasound localization techniques used in image-guided breast biopsies?

<p>When a mass is present (C)</p> Signup and view all the answers

Why is mammographic evaluation limited for women with a strong family history of breast cancer or known genetic mutations?

<p>Because of the increased breast density in younger women (B)</p> Signup and view all the answers

What are the four levels of afferent lymphatic channels in the breast?

<p>Dermal, subdermal, interlobular, prepectoral (D)</p> Signup and view all the answers

Where do lymphatic dyes injected in the breast travel to?

<p>Same axillary nodes (B)</p> Signup and view all the answers

What happens to breast cancers at approximately the twentieth cell doubling?

<p>They develop neovascularization (C)</p> Signup and view all the answers

How do cancer cells travel to seed distant metastases?

<p>Via lymphatic vessels (D)</p> Signup and view all the answers

What is the most common cause of death in breast cancer patients for the first 10 years after treatment?

<p>Distant metastases (A)</p> Signup and view all the answers

Why are conclusive results from breast cancer trials not derived until 5 to 10 years have passed?

<p>To allow for distant metastases to occur (B)</p> Signup and view all the answers

What is a significant factor in determining whether breast-conserving therapy is feasible?

<p>The relationship between tumor size and breast size (C)</p> Signup and view all the answers

Why might preoperative chemotherapy be considered for patients with large tumors?

<p>To decrease the tumor size before surgery (C)</p> Signup and view all the answers

What is a consideration when dealing with patients with multicentric tumors?

<p>Opting for mastectomy due to the complexity of the situation (B)</p> Signup and view all the answers

Why is pregnancy an absolute contraindication to radiation therapy?

<p>To avoid fetal exposure to radiation (B)</p> Signup and view all the answers

In what situation may local tissue rearrangement or pedicled myocutaneous flaps be considered?

<p>To address defects from breast-conserving surgery (B)</p> Signup and view all the answers

How does chemotherapy administered before surgery affect breast-conserving surgery candidates?

<p>It reduces tumor size to permit surgery (C)</p> Signup and view all the answers

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