Factors Affecting Histopathology Fixation Duration

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11 Questions

What is the purpose of placing cotton or cotton balls inside the open organ during fixation?

To facilitate faster fixation

How are hard tissues like nails and bones prepared for fixation?

Washed in running water and immersed in tissue softeners

What is the classification of fixatives based on their function?

Additive and non-additive

Which fixative is described as becoming a part of the tissue?

Formalin

What distinguishes compound fixatives from simple fixatives in terms of composition?

Compound fixatives are made of two or more fixatives, while simple fixatives are single component.

What factor hastens or speeds up the duration of fixation?

Agitation

Which factor retards or slows down fixation?

Fibrous tissue samples

What is the most ideal specimen to fixative ratio according to the text?

1:20

Which special consideration is mentioned for brain fixation?

Suspended in whole and tied

What enhances the infiltration of fixatives in solid tissues like the uterus?

Cutting open the tissue

In what range is the specimen to fixative ratio for expensive stain like osmium tetroxide set?

1:5-10 times

Learn about factors that can either speed up or slow down the duration of fixation in histopathology labs. Understand how the presence of certain tissues or techniques such as vacuum fixation can impact the fixation process.

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