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Factors Affecting Drug Danger

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Questions and Answers

Which of the following factors significantly contribute to the potential danger of a pharmaceutical material?

Slow onset of overdose symptoms

Availability to suicidal patients (correct)

High therapeutic index

Low potency

What are the characteristics of a pharmaceutical material that makes its overdose particularly dangerous?

Rapid onset of symptoms, no readily available antidote (correct)

Slow onset of symptoms, readily available antidote

Limited availability, high therapeutic index

Low potency, high therapeutic index

Which of the following is NOT a factor that directly influences the potential danger of a pharmaceutical material?

Dosage form (correct)

Availability to suicidal patients

Therapeutic index

Potency

Why might drugs used by severely ill individuals pose a higher risk?

<p>They may have a low therapeutic index and require careful monitoring (B)</p> Signup and view all the answers

What is the significance of drug interactions in assessing the potential danger of a pharmaceutical material?

<p>Drug interactions can lead to unpredictable and potentially harmful effects (C)</p> Signup and view all the answers

Flashcards

Low therapeutic index

A measure indicating the safety margin of a drug; a small difference between effective and toxic doses.

High potency

Drugs that produce significant effects even at low doses, increasing their potential for danger.

Access to at-risk patients

Availability of drugs to individuals with suicidal tendencies or severe depression, raising safety concerns.

Overdose symptoms

Signs of drug overdose that appear quickly and can be severe; often without an antidote available.

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Drug interactions

The effects that occur when one drug alters the action of another, potentially causing harmful consequences.

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Study Notes

Factors Affecting Drug Danger

Low therapeutic index: Indicates a narrow margin of safety between a drug's effective dose and its toxic dose. This increases the risk of adverse effects.
High potency: Means a drug is effective in small doses. High potency can lead to more dangerous side effects, particularly with accidental or intentional overdoses.
Patient vulnerability: Access by suicidal or depressed individuals greatly increases the risk of accidental or intentional misuse and harm.
Patient population: Severe illnesses often necessitate the use of potentially dangerous drugs. However, careful monitoring and strict adherence to protocol to limit patient exposure are still critical.
Overdose characteristics: Symptoms are severe, rapid in onset, lack an effective antidote, and occur quickly. These rapid and severe reactions greatly raise the potential for fatal consequences.
Drug interactions: Simultaneous use of multiple medications can lead to unpredictable and potentially dangerous reactions. Careful consideration of all possible interactions is crucial.

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Description

This quiz explores the various factors that influence the danger level of medications. Key aspects include therapeutic indexes, drug potency, patient vulnerabilities, and drug interactions. Understanding these elements is crucial for ensuring drug safety and minimizing risks.