Eye Microanatomy- Pt 1
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Questions and Answers

What forms the lens, cornea outer epithelium, and palpebrae epithelium in embryology?

  • Ectoderm (correct)
  • Endoderm
  • Neuroectoderm
  • Mesoderm
  • Which layer of the eye is composed of the retina and pigment epithelium?

  • Outer fibrous tunic
  • Inner retinal tunic
  • Middle vascular tunic
  • Optic cup (correct)
  • What is the term for the supporting structures of the eye?

  • Adnexa (correct)
  • Lens
  • Sclera
  • Retina
  • What is the order of eye color, from least pigmented to most pigmented?

    <p>Blue, gray, green, brown</p> Signup and view all the answers

    What forms the optic nerve in embryology?

    <p>Optic stalk</p> Signup and view all the answers

    What is the term for the boney socket in the skull that contains the eyeball?

    <p>Orbit</p> Signup and view all the answers

    What is the location of the ciliary processes?

    <p>At the base of the iris</p> Signup and view all the answers

    What is the significance of knowing the eye layers in ocular diagnosis?

    <p>To determine the severity of a corneal ulcer</p> Signup and view all the answers

    What type of cells are responsible for forming the aqueous humor?

    <p>Nonpigmented cells</p> Signup and view all the answers

    Which of the following structures is NOT part of the drainage pathway of aqueous humor?

    <p>Macula</p> Signup and view all the answers

    What is the role of Amacrine cells in the optical retina?

    <p>Act as interneurons</p> Signup and view all the answers

    What is the primary function of the aqueous humor?

    <p>To nourish the cornea and lens</p> Signup and view all the answers

    What is the composition of the sclera?

    <p>A layer of dense irregular connective tissue</p> Signup and view all the answers

    Which of the following tunics is NOT part of the eye?

    <p>Muscular tunic</p> Signup and view all the answers

    What is the pathway of light through the retina?

    <p>Photoreceptor cells -&gt; bipolar neurons -&gt; ganglion cells</p> Signup and view all the answers

    What is the primary function of the adenosine triphosphatase and carbonic anhydrase pumps in the cornea?

    <p>To maintain the relative dehydration of the cornea</p> Signup and view all the answers

    What is the main reason for the transparency of the cornea?

    <p>The lack of blood vessels</p> Signup and view all the answers

    What is the function of the posterior limiting membrane (Descemet's membrane)?

    <p>It supports the endothelium</p> Signup and view all the answers

    Which layer of the cornea is composed primarily of Type 1 collagen?

    <p>Substantia propria</p> Signup and view all the answers

    What is the primary function of the limbus?

    <p>To provide nutrition to the cornea</p> Signup and view all the answers

    What is the primary function of the choroid?

    <p>To provide nutritional support to the retina</p> Signup and view all the answers

    Which part of the retina is responsible for sending visual images to the brain?

    <p>Sensory/optic part</p> Signup and view all the answers

    What is the result of the lack of melanin pigment in the eyes of individuals with albinism?

    <p>Red-colored eyes</p> Signup and view all the answers

    Which of the following is NOT a part of the choroid?

    <p>Posterior</p> Signup and view all the answers

    What is the function of the iridocorneal angle?

    <p>To drain aqueous humor</p> Signup and view all the answers

    What is the composition of the stroma in the iris?

    <p>Pigment of loose connective tissue</p> Signup and view all the answers

    What is the role of the vitreous body in the eye?

    <p>To hold the retina in place</p> Signup and view all the answers

    What is the function of the ciliary muscle during accommodation?

    <p>Decreases the tension of the zonular fibers</p> Signup and view all the answers

    What is the sensory innervation of the cornea?

    <p>Cranial nerve 5 (trigeminal nerve)</p> Signup and view all the answers

    What is the composition of the iridocorneal angle?

    <p>Pectinate ligament, trabecular meshwork, and trabecular veins</p> Signup and view all the answers

    What is the function of the ciliary body?

    <p>To house the ciliary muscle and have mechanical and secretory functions</p> Signup and view all the answers

    What does the boxed section of this image represent?

    <p>Fibrous tunic</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Anterior epithelium</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Substantia propria</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Posterior epithelium</p> Signup and view all the answers

    What is number 4 referring to?

    <p>Descemet's membrane</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Anterior corneal epithelium</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Anterior limiting membrane</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Stroma</p> Signup and view all the answers

    What is number 4 referring to?

    <p>Descemet's membrane</p> Signup and view all the answers

    What is number 5 referring to?

    <p>Posterior epithelium</p> Signup and view all the answers

    What is this an image of?

    <p>Collagenous laminae</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Anterior chamber</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Iris</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Posterior chamber</p> Signup and view all the answers

    What is letter "A" referring to?

    <p>Sclera</p> Signup and view all the answers

    What is letter "B" referring to?

    <p>Retina</p> Signup and view all the answers

    What is letter "C" referring to?

    <p>Optic disk</p> Signup and view all the answers

    What is letter "D" referring to?

    <p>Ciliary body and processes</p> Signup and view all the answers

    What is letter "E" referring to?

    <p>Lens</p> Signup and view all the answers

    What is letter "F" referring to?

    <p>Iris</p> Signup and view all the answers

    What is letter "G" referring to?

    <p>Anterior chamber</p> Signup and view all the answers

    What is letter "H" referring to?

    <p>Cornea</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Optic nerve</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Lens</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Ciliary body</p> Signup and view all the answers

    What is number 4 referring to?

    <p>Iris</p> Signup and view all the answers

    What is number 5 referring to?

    <p>Cornea</p> Signup and view all the answers

    What is the circled part of this image referring to?

    <p>Ciliary processes</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Body of lens</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Lens epithelium</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Ciliary processes</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Non-pigmented epithelial cells</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Pigmented epithelial cells</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Pigmented epithelium</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Choroid</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Sclera</p> Signup and view all the answers

    What is number 4 referring to?

    <p>Retina</p> Signup and view all the answers

    What is letter "A" referring to?

    <p>Sclera</p> Signup and view all the answers

    What is letter "B" referring to?

    <p>Choroid</p> Signup and view all the answers

    What is letter "C" referring to?

    <p>Retina</p> Signup and view all the answers

    What is number 1 referring to?

    <p>Retina</p> Signup and view all the answers

    What is number 2 referring to?

    <p>Retinal pigment epithelium</p> Signup and view all the answers

    What is number 3 referring to?

    <p>Choroid</p> Signup and view all the answers

    What is letter "A" referring to?

    <p>Choroidal pigment</p> Signup and view all the answers

    What is letter "B" referring to?

    <p>Choroidal vessels</p> Signup and view all the answers

    What is letter "C" referring to?

    <p>Cellular tapetum</p> Signup and view all the answers

    What is letter "D" referring to?

    <p>Retina</p> Signup and view all the answers

    What is letter "A" referring to?

    <p>Ciliary processes</p> Signup and view all the answers

    What is letter "B" referring to?

    <p>Lens</p> Signup and view all the answers

    What is letter "C" referring to?

    <p>Ciliary body</p> Signup and view all the answers

    The sclera is the posterior portion of the eye, while the cornea is the anterior portion of the eye.

    <p>True</p> Signup and view all the answers

    Study Notes

    Eye Development (Embryology)

    • Ectoderm forms the lens, cornea outer epithelium, and palpebrae epithelium (eyelids)
    • Mesoderm forms the corneal stroma, sclera, extraocular muscles, ciliary muscles, and tunica vasculosa
    • Neuroectoderm of diencephalon forms the optic cup, which remains connected to the optic stalk
    • Optic cup has two layers: retina and pigment epithelium
    • Optic stalk forms the optic nerve

    Eye: General Info

    • The eyeball (globe) is located in the skull's boney socket, known as the orbit
    • The eye is composed of a lens, and three layers: outer fibrous tunic, middle vascular (uveal) tunic, and inner retinal (neuroepithelial) tunic
    • Adnexa (accessory ocular structures) are the supporting structures, including palpebrae (eyelids), third eyelid and conjunctiva, and the lacrimal apparatus
    • Knowing the eye layers is important for clinical diagnosis, such as determining the severity of a corneal ulcer

    Eye Color

    • Eye color follows the trend: blue, gray, green, brown iris, with blue iris having minimal pigment in the stroma of the iris

    Ciliary Processes

    • Ciliary processes are located at the base of the iris
    • Epithelial surface of ciliary processes has two layers of low columnar epithelium, which can be pigmented or nonpigmented
    • Nonpigmented epithelium forms aqueous humor, while pigmented epithelium forms zonular fibers that suspend the lens

    Aqueous Humor

    • Aqueous humor occupies the anterior and posterior chambers of the eye, nourishing the cornea and lens
    • Aqueous humor maintains the intraocular pressure and is formed by non-pigmented cells of the ciliary processes
    • Aqueous humor requires constant drainage at the iridocorneal angle

    Drainage Pathway of Aqueous Humor

    • Aqueous humor drains from the posterior chamber, through the pupil, to the anterior chamber, to the iridocorneal angle, past the pectinate ligaments, to the scleral venous plexus

    Optical Retina

    • Light passes through layers of the retina, stimulating photoreceptor cells (rods and cones)
    • Impulse is passed to bipolar neurons, then to ganglion cells
    • Axons of ganglionic cells form the nerve fiber layer, where these layers converge at the optic disk (papilla) and leave the eye as the optic nerve (cranial nerve 2)
    • Additional cells with supporting roles include Amacrine cells (interneurons), horizontal cells (regulate input from photoreceptor cells), and Muller cells (glial cells)

    Eye: Tunics

    • The eye tunics include the: fibrous tunic, vascular (uveal) tunic, and neuroepithelial (retinal) tunic

    Fibrous Tunic

    • The fibrous tunic is composed of the sclera, cornea, and limbus
    • Sclera is the posterior portion of the eye, composed of a white opaque layer of dense irregular connective tissue
    • Sclera functions include eye protection, maintaining eye shape, and providing insertion point for extraocular muscle tendons
    • Cornea is the anterior portion of the eye, avascular and transparent
    • Cornea is richly supplied with sensory nerves (from the ophthalmic branch of cranial nerve 5)
    • Cornea is highly capable of regenerating
    • Cornea is composed of five layers: anterior corneal epithelium, anterior limiting lamina/subepithelial basement membrane, substantia propria, posterior limiting membrane (Descemet's membrane), and posterior epithelium (corneal endothelium)

    Limbus (Corneoscleral Junction)

    • Limbus is where the opaque sclera overlaps the transparent cornea
    • Limbus has small blood vessels
    • Nutrition from the cornea comes from the microvasculature of the limbus and aqueous humor
    • Epithelium of the limbus is continuous with the conjunctiva that lines the eyelids

    Vascular (Uveal) Tunic

    • The vascular tunic is composed of the iridocorneal angle, iris, ciliary body, and choroid
    • Iris contains the stroma, which is a pigment of loose connective tissue
    • Iridial melanin is present in the stromal cells, determining the eye's color
    • Iris has dilators and sphincter pupillae muscles
    • Posterior epithelium of the iris contains iridic granules (corpora nigra), present in equids and ruminants at the dorsal ventral pupillary margins
    • Iridocorneal angle is also known as the filtration angle or drainage angle
    • Iridocorneal angle is located at the convergence of corneoscleral junction (limbus), ciliary body, and the iris
    • Iridocorneal angle is composed of pectinate ligament, trabecular meshwork, and trabecular (aqueous) veins
    • Iridocorneal angle functions as a drainage point for aqueous humor

    Ciliary Body

    • Ciliary body is the anterior expansion of the choroid at the level of the lens, containing mechanical and secretory functions
    • Ciliary body houses the ciliary muscle, which is composed of smooth muscle, surrounded by loose connective tissue (elastic fibers, vessels, and melanocytes)
    • Ciliary muscle contracts during accommodation, reducing the tension of the zonular fibers of the lens
    • Ciliary muscle receives innervation from cranial nerve 3 (oculomotor nerve)
    • Posterior pigmented epithelium of the iris is continuous with the nonpigmented epithelium of the ciliary body

    Choroid

    • Choroid is highly vascularized, functioning as the nutritional source for the retina
    • Choroid contains four parts: anterior, external, internal, and internal to vascular layer (tapetum lucidum)

    Neuroepithelial (Retinal) Tunic

    • Retina has three parts: sensory/optic, non-sensory/ciliary, and non-sensory/iridal
    • Sensory/optic part contacts the choroid, sending visual images to the brain, and is composed of 10 layers held in place by the vitreous body
    • Combined nerve fiber layers converge on the optic disk to form the optic nerve
    • Non-sensory/ciliary part consists of inner nonpigmented and outer pigmented ciliary epithelium "pars ciliaris retinae"
    • Non-sensory/iridal part consists of posterior pigmented epithelium "pars iridica retinae"

    Albinism

    • Albinism is an inherited congenital disorder, characterized by a partial or total lack of melanin pigment in the eyes, skin, and hair
    • Albinos have melanocytes, which produce melanin, but lack genes for tyrosinase
    • Albinism results from inheritance of recessive alleles
    • Red-colored eyes are a result of the lack of melanin pigment in the eyes, including the iris
    • The red coloration is due to hemoglobin in the red blood cells

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    Description

    This quiz covers the formation of eye structures from ectoderm, mesoderm, and neuroectoderm in embryology. Learn about the development of the lens, cornea, sclera, and optic cup.

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