OMFS and Ophthalmology - Overview
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A patient presents with diplopia and enophthalmos following a sports injury involving blunt force to the eye. Which of the following is the MOST appropriate initial management strategy?

  • Immediate administration of high-dose intravenous corticosteroids.
  • Prescription of prism glasses to correct the double vision.
  • Surgical repair with titanium mesh or bone graft. (correct)
  • Conservative management with observation and pain control.

An elderly patient reports sudden onset of severe eye pain, blurred vision, and seeing halos around lights. Examination reveals a closed anterior chamber angle. Which of the following is the MOST appropriate first-line treatment?

  • Urgent administration of intravenous acetazolamide. (correct)
  • Topical application of lubricating eye drops and close monitoring.
  • Surgical phacoemulsification to remove a cataract.
  • Intravitreal injection of anti-VEGF medication.

Which of the following is the MOST effective preventative measure for cataracts?

  • Regular intraocular pressure checks
  • Use of UV protection (correct)
  • High dose Vitamin C supplementation
  • Yearly eye exams with pupil dilation

A patient diagnosed with the 'wet' form of age-related macular degeneration (AMD) would MOST likely benefit from which of the following treatments?

<p>Intravitreal injections of anti-VEGF medications. (D)</p> Signup and view all the answers

An elderly patient presents with sudden vision loss, headache, scalp tenderness, and jaw claudication. Laboratory results show a markedly elevated ESR. Which of the following is the MOST appropriate initial treatment?

<p>Immediate administration of high-dose corticosteroids. (C)</p> Signup and view all the answers

A patient presents with a painful, maculopapular rash along the forehead and periorbital region, accompanied by conjunctivitis and decreased vision. Which of the following is the MOST likely diagnosis?

<p>Herpes zoster ophthalmicus. (C)</p> Signup and view all the answers

Following a motorcycle accident, a patient's ocular examination reveals diplopia and limited upward gaze in the right eye. Imaging confirms a fracture of the orbital floor. Which of the following mechanisms MOST likely explains the patient's diplopia?

<p>Entrapment of the inferior rectus muscle within the fracture site. (C)</p> Signup and view all the answers

A patient with age-related macular degeneration (AMD) is advised to modify their lifestyle. Which of the following recommendations would be MOST beneficial in slowing the progression of AMD?

<p>Quit smoking and adhere to a healthy diet (D)</p> Signup and view all the answers

A patient presents with dry eyes and dry mouth. Which of the following is the MOST likely underlying cause?

<p>Sjogren’s syndrome (A)</p> Signup and view all the answers

A patient is diagnosed with a benign pleomorphic adenoma in the lacrimal gland. What is the PRIMARY treatment approach?

<p>Surgical excision (A)</p> Signup and view all the answers

A patient presents with orbital cellulitis secondary to ethmoid sinusitis. What is the INITIAL step in management?

<p>Initiation of intravenous antibiotics (D)</p> Signup and view all the answers

What is the MOST appropriate treatment for Ramsay Hunt syndrome?

<p>Intravenous acyclovir and corticosteroids (C)</p> Signup and view all the answers

What is the PRIMARY purpose of using titanium mesh or bone grafts in the repair of orbital floor fractures?

<p>To restore normal orbital anatomy and prevent enophthalmos/diplopia (C)</p> Signup and view all the answers

In cases of severe inflammatory eye disease, what is the MAIN reason for using high-dose IV methylprednisolone or oral steroids?

<p>To provide strong immunosuppression and reduce arterial inflammation (C)</p> Signup and view all the answers

Which medication is typically used as a prophylaxis for steroid side effects during long-term steroid therapy?

<p>Bisphosphonates (D)</p> Signup and view all the answers

How does acyclovir work in treating herpes zoster ophthalmicus or Ramsay Hunt syndrome?

<p>It inhibits viral DNA polymerase. (A)</p> Signup and view all the answers

What is the MOST important purpose of surgical drainage in the management of orbital cellulitis?

<p>To physically evacuate abscess, relieving pressure and infection (C)</p> Signup and view all the answers

What is the PRIMARY mechanism of action of anti-VEGF injections?

<p>To block vascular endothelial growth factor, reducing abnormal blood vessel growth. (C)</p> Signup and view all the answers

Which of the following mechanisms is the PRIMARY reason for vision loss in untreated giant cell arteritis?

<p>Ischemic optic neuropathy secondary to arterial inflammation (B)</p> Signup and view all the answers

A patient presents with acute angle-closure glaucoma. After initiating initial medical management, what is the definitive treatment to prevent future episodes?

<p>Peripheral iridotomy via laser or surgery (C)</p> Signup and view all the answers

Which of the following is the MOST significant risk factor for developing the 'wet' form of age-related macular degeneration (AMD)?

<p>Advanced age and genetic predisposition (D)</p> Signup and view all the answers

What is the PRIMARY mechanism by which UV exposure contributes to cataract formation?

<p>Induction of oxidative stress and protein denaturation in the lens (A)</p> Signup and view all the answers

What is the MOST common long-term complication following surgical repair of an orbital floor fracture?

<p>Recurrence of diplopia (B)</p> Signup and view all the answers

A patient with herpes zoster ophthalmicus develops acute vision loss and is found to have acute retinal necrosis (ARN). What is the MOST appropriate modification to their treatment?

<p>Initiate intravenous antiviral therapy (C)</p> Signup and view all the answers

Following blunt trauma to the eye, a patient exhibits enophthalmos and diplopia despite no radiographic evidence of orbital fracture. Which of the following is the MOST likely explanation for these findings?

<p>Soft tissue injury with orbital fat atrophy and muscle contusion (D)</p> Signup and view all the answers

A patient with long-standing diabetes mellitus presents with progressive, painless vision loss. Examination reveals bilateral lens opacities that appear similar to looking through a frosted window. Which of the following metabolic derangements is MOST directly implicated in the pathogenesis of this type of cataract?

<p>Increased aldose reductase activity converting glucose to sorbitol in the lens (C)</p> Signup and view all the answers

The hallmark symptoms of Sjogren’s Syndrome are caused by autoimmune damage to which type of glands?

<p>Exocrine glands, such as lacrimal and salivary glands. (D)</p> Signup and view all the answers

What is the primary treatment strategy for managing the dry eye symptoms associated with Sjogren's Syndrome?

<p>Symptomatic lubrication with artificial tears. (B)</p> Signup and view all the answers

A patient presents with painless swelling near the outer, upper eyelid. Which of the following conditions should be HIGHLY suspected?

<p>Benign lacrimal gland tumour, such as pleomorphic adenoma. (D)</p> Signup and view all the answers

Which of the following is the MOST common etiology of orbital cellulitis?

<p>Spread of infection from adjacent sinuses (D)</p> Signup and view all the answers

A patient presents with ear vesicles, facial paralysis, and is diagnosed with Ramsay Hunt syndrome. Which antiviral medication is MOST appropriate?

<p>Acyclovir (A)</p> Signup and view all the answers

What is the MAIN purpose of using titanium mesh in the repair of orbital floor fractures?

<p>To restore normal orbital anatomy and prevent enophthalmos or diplopia. (C)</p> Signup and view all the answers

In severe inflammatory eye disease, high-dose IV methylprednisolone or oral steroids are used primarily for what purpose?

<p>To suppress the immune system, reducing arterial inflammation and preventing further vision loss. (C)</p> Signup and view all the answers

Why is surgical drainage considered urgent in orbital cellulitis complicated by abscess formation?

<p>To decompress the orbit, preventing optic nerve damage and vision loss. (D)</p> Signup and view all the answers

A patient with macular degeneration is receiving anti-VEGF injections. What is the PRIMARY mechanism of action of these injections?

<p>To block vascular endothelial growth factor, reducing abnormal blood vessel growth and leakage. (D)</p> Signup and view all the answers

A patient presents with sudden vision loss, headache, scalp tenderness and is suspected of having giant cell arteritis (GCA). Before laboratory results are available, and after administering oxygen and aspirin, what is the MOST appropriate next step in management?

<p>Initiate high-dose corticosteroids immediately, without waiting for lab confirmation (B)</p> Signup and view all the answers

Flashcards

Orbital Blowout Fracture

Fracture of the orbital floor/medial wall, possibly trapping fat or eye muscles after trauma.

Diplopia

Double vision, often due to eye misalignment from muscle or nerve issues.

Acute Glaucoma (Closed-Angle)

Rapid increase in eye pressure due to blocked drainage, causing sudden vision problems.

Cataract

Clouding of the lens, reducing clarity.

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Macular Degeneration (AMD)

Degeneration of the central retina (macula), leading to central vision loss.

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Giant Cell Arteritis

Inflammation of medium/large arteries, especially in the head, risking blindness.

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Herpes Zoster Ophthalmicus

Reactivation of chickenpox virus in the trigeminal nerve, potentially affecting the eye.

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Cataract

Opacification of the lens, reduces vision.

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Sjogren's Syndrome

Autoimmune damage to glands, causing dry eyes and mouth.

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Lacrimal Gland Tumours

Tumors in the lacrimal gland; can be benign or malignant.

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Orbital Cellulitis

Infection within the eye socket, often from sinus infections.

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Ramsay Hunt Syndrome

Herpes zoster reactivation affecting the facial nerve, causing paralysis.

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Titanium Mesh/Bone Graft

Used to repair fractures around the eye, preventing complications.

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IV Methylprednisolone

Strongly suppresses the immune system to reduce inflammation.

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Prophylaxis for Steroid Side Effects

Prevents bone loss and stomach ulcers during steroid treatment

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Acyclovir

Antiviral drug used for infections like herpes zoster.

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Surgical Drainage

Physically removes pus to relieve pressure from infection.

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Anti-VEGF Injections

Blocks VEGF to reduce abnormal blood vessel growth in the retina.

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Acute Angle Closure Glaucoma

Sudden increase in eye pressure due to blocked drainage.

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IV Acetazolamide

Medication used to lower eye pressure quickly in acute glaucoma.

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Keratoconjunctivitis Sicca/Xerostomia

Dry eyes and mouth due to autoimmune damage of lacrimal and saliva glands.

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Lacrimal Gland Tumour Excision

Surgical removal of a mass from the lacrimal gland.

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Early Sign of Lacrimal Tumours

Swelling near the outer, upper eyelid area.

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IV Antibiotics for Orbital Cellulitis

Bacterial pathogens targeted in the space behind the eye.

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Titanium Mesh/Bone Graft Function

Restores orbital anatomy and prevents eye complications after fractures.

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IV Methylprednisolone Mechanism

Reduces inflammation by suppressing the immune system.

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Phacoemulsification

Removes clouded lens with ultrasonic waves, replaces it with a clear one.

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Study Notes

  • The following are key facts regarding eye-related conditions, drugs, treatments, and tests

Orbital Blowout Fracture

  • Fracture of the orbital floor or medial wall after trauma
  • Possible entrapment of fat or extraocular muscles
  • Caused by blunt injuries like sports accidents or assaults
  • Treat with surgical repair using titanium mesh or bone graft if needed
  • Surgical repair is crucial if diplopia or enophthalmos develops
  • Prevent via eye protection during risky activities
  • Prompt evaluation of facial trauma is essential for prevention

Diplopia

  • Double vision
  • Often due to misalignment of the eyes
  • Misalignment results from extraocular muscle restriction or nerve impairment
  • Caused by orbital fractures, nerve palsies, or muscle entrapment
  • Treat the underlying cause, such as fracture repair or strabismus correction
  • Prevent with protective gear to avoid eye trauma

Acute Glaucoma (Closed-Angle)

  • Rapid rise in intraocular pressure (IOP) because of blocked drainage angle
  • Narrow anterior chamber angle or iris occluding outflow causes it
  • Treat with urgent medication like IV acetazolamide, laser, or surgical intervention
  • Prevent through screening in high-risk individuals with family history or narrow angles

Cataract

  • Opacification of the lens, reducing light transmission and clarity
  • Age-related changes, trauma, or UV exposure causes it
  • Treat with surgical removal (phacoemulsification) and replacement with a plastic intraocular lens
  • Prevent with UV protection and managing metabolic disorders like diabetes

Macular Degeneration (AMD)

  • Degeneration of the macula, the central portion of the retina
  • Causes central vision loss
  • Age or family history causes AMD
  • "Wet" type involves abnormal choroidal neovascularization
  • Limited treatment includes anti-VEGF injections for "wet" AMD and nutritional support
  • Prevent with a healthy diet, no smoking, and regular eye exams for early detection

Giant Cell Arteritis (Temporal Arteritis)

  • Vasculitis of medium/large arteries
  • Especially affects branches of the external carotid artery
  • Risk of irreversible blindness
  • Immune-mediated inflammation
  • Typically occurs in older adults
  • Treat with high-dose corticosteroids like IV methylprednisolone, then taper over months or years
  • Use prophylaxis for steroid side effects
  • No definitive prevention
  • Early recognition (scalp tenderness, jaw claudication, high ESR) is crucial to save vision

Herpes Zoster Ophthalmicus

  • Reactivation of the varicella-zoster virus in the trigeminal ophthalmic division
  • Risks corneal involvement and blindness
  • Immunocompromise or reactivation of latent virus causes it
  • Treat with high-dose aciclovir and analgesia
  • Urgent ophthalmic review is needed for potential eye complications
  • Prevent with shingles vaccination in eligible adults

Sjogren’s Syndrome

  • Autoimmune damage to exocrine glands (lacrimal, salivary)
  • Causes dry eyes (keratoconjunctivitis sicca) and mouth (xerostomia)
  • Autoimmune etiology
  • Treat with symptomatic lubrication (artificial tears)
  • Use immunosuppressants if severe
  • Watch for lymphoma
  • Not preventable
  • Early detection helps manage dryness complications

Lacrimal Gland Tumours

  • Neoplasms in the lacrimal gland such as pleomorphic adenoma (benign but can grow)
  • Cause is unknown
  • Some can be malignant (adenoid cystic, adenocarcinoma, lymphoma)
  • Treat with surgical excision
  • Use radiotherapy or chemotherapy if malignant
  • Early detection of painless swelling near the outer upper eyelid area is important

Orbital Cellulitis

  • Infection within the orbit, posterior to the orbital septum
  • Often spreads from sinus infections (ethmoid) or local trauma
  • Treat with IV antibiotics
  • Urgent surgical drainage if abscess is present
  • Prevent with prompt treatment of sinusitis and good infection control

Ramsay Hunt Syndrome (Type 2)

  • Herpes zoster infection of the facial nerve (geniculate ganglion)
  • Can involve ear vesicles and facial paralysis
  • Reactivation of VZV causes it
  • Treat with antivirals like IV aciclovir
  • Corticosteroids are often used
  • Prevent with varicella-zoster vaccination
  • Utilize early antiviral therapy if herpes zoster is suspected

Titanium Mesh / Bone Graft

  • Used for repair of orbital floor fractures
  • Mechanism: Restores normal orbital anatomy and prevents enophthalmos/diplopia

IV Methylprednisolone / Oral Steroids

  • Used for high-dose treatment in giant cell arteritis, severe inflammatory eye disease
  • Mechanism: Strong immunosuppression to reduce arterial inflammation and prevent further vision loss

Prophylaxis for Steroid Side Effects (Bisphosphonates, GI protectants)

  • Used to prevent osteoporosis (bisphosphonates) and peptic ulcers (e.g., PPIs) during long-term steroid therapy

Acyclovir (IV/Oral)

  • Used for herpes zoster ophthalmicus, Ramsay Hunt syndrome
  • Mechanism: Antiviral that inhibits viral DNA polymerase

Surgical Drainage (e.g., Orbital Cellulitis)

  • Used for removing purulent collections threatening vision
  • Mechanism: Physically evacuates abscess, reducing pressure and infection load

IV Antibiotics

  • Used for orbital cellulitis (sinus-based infection)
  • Mechanism: Targets bacterial pathogens to control sepsis in the orbital region

Phacoemulsification

  • Used for cataract surgery
  • Mechanism: Ultrasonic fragmentation of the clouded lens, replaced with a clear artificial lens

Anti-VEGF Injections

  • Used for wet macular degeneration
  • Mechanism: Blocks vascular endothelial growth factor, reducing abnormal blood vessel growth/leakage in the retina

Eye/Visual Tests (Snellen chart, fundoscopy)

  • Used to assess visual acuity and examine retinal health
  • Mechanism: Basic clinical tools to quantify vision (Snellen) and inspect internal eye structures (fundoscopy)

CT Scan (Orbital Imaging)

  • Used for detecting blowout fractures, sinus involvement, or lacrimal gland tumours
  • Mechanism: Cross-sectional X-ray imaging reveals fractures and soft-tissue detail

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Description

Key facts regarding eye-related conditions like orbital blowout fractures and acute glaucoma. Includes causes, treatments such as surgical repair, and preventive measures like eye protection. Also covers diplopia and the importance of prompt evaluation after facial trauma.

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