Extracellular Fluid Constituents Quiz

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Questions and Answers

What is the approximate nonlethal limit range for oxygen levels in mm Hg?

  • 40–60
  • 35–45
  • 5–80
  • 10–1000 (correct)

Which ion has an average normal value of 1.2 mmol/L?

  • Calcium ion (correct)
  • Potassium ion
  • Sodium ion
  • Bicarbonate ion

What is the normal range for bicarbonate ion levels in mmol/L?

  • 24–32 (correct)
  • 28–35
  • 22–30
  • 20–30

What is the average normal value for potassium ion in mmol/L?

<p>4.2 (D)</p> Signup and view all the answers

What is the average body temperature in Fahrenheit?

<p>98.4 (B)</p> Signup and view all the answers

Which pH value indicates a normal acid-base balance in the body?

<p>7.4 (D)</p> Signup and view all the answers

What is the approximate nonlethal limit for glucose levels in mg/dL?

<p>20–1500 (C)</p> Signup and view all the answers

Which ion has the normal range of 138–146 mmol/L?

<p>Sodium ion (A)</p> Signup and view all the answers

What is the primary purpose of the Pocket Companion to Guyton and Hall Textbook of Medical Physiology?

<p>To summarize key concepts from the main textbook (C)</p> Signup and view all the answers

Who is the author of the Pocket Companion to Guyton and Hall Textbook of Medical Physiology?

<p>John E. Hall (B)</p> Signup and view all the answers

Which organization published the Pocket Companion to Guyton and Hall Textbook of Medical Physiology?

<p>Elsevier Inc. (D)</p> Signup and view all the answers

What should practitioners be mindful of when using the information from this publication?

<p>Their own safety and that of others (A)</p> Signup and view all the answers

What does the copyright notice indicate about the content of the Pocket Companion?

<p>The content is protected and requires permission for reproduction (C)</p> Signup and view all the answers

What is stated about the knowledge and best practices in the field of physiology?

<p>They are constantly evolving and require adaptation (C)</p> Signup and view all the answers

What is the significance of the ISBN number found in the Pocket Companion?

<p>It serves as a unique identifier for the book (A)</p> Signup and view all the answers

In what year was the most recent edition of the Pocket Companion published?

<p>2012 (B)</p> Signup and view all the answers

Where is most of the ATP produced in the cell formed?

<p>In the mitochondria (B)</p> Signup and view all the answers

What is the initial product of glycolysis?

<p>Pyruvic acid (B)</p> Signup and view all the answers

Which cycle involves the conversion of acetyl-CoA into hydrogen ions and carbon dioxide?

<p>Citric acid cycle (B)</p> Signup and view all the answers

What role do hydrogen ions play in ATP synthesis?

<p>They drive the conversion of ADP to ATP (C)</p> Signup and view all the answers

Which cellular function is NOT directly promoted by ATP?

<p>Cell division (A)</p> Signup and view all the answers

What is the primary function of the agranular, or smooth, ER?

<p>Synthesis of lipid substances (D)</p> Signup and view all the answers

How does ATP synthetase contribute to ATP production?

<p>It uses energy from hydrogen ion movement to convert ADP to ATP (A)</p> Signup and view all the answers

What is the final product when hydrogen ions combine with oxygen in the mitochondria?

<p>Water (A)</p> Signup and view all the answers

What characterizes the Golgi apparatus in relation to secretory cells?

<p>It has membranes similar to those of the agranular ER. (C)</p> Signup and view all the answers

What do lysosomes primarily contain that aids in their function?

<p>Digestive enzymes (A)</p> Signup and view all the answers

What is the chemosmotic mechanism primarily responsible for?

<p>ATP formation (D)</p> Signup and view all the answers

What happens to lysosomal enzymes if the membranes surrounding them are damaged?

<p>They leak out and can digest nearby substances. (D)</p> Signup and view all the answers

What is primarily removed during the citric acid cycle in the mitochondria?

<p>Carbon dioxide and hydrogen ions (D)</p> Signup and view all the answers

Which food source is NOT mentioned as providing energy for the cell?

<p>Cellulose from plants (B)</p> Signup and view all the answers

What role do small transport vesicles play in relation to the Golgi apparatus?

<p>They transport substances from the ER to the Golgi apparatus. (D)</p> Signup and view all the answers

What is the primary function of mitochondria in cells?

<p>Energy production (C)</p> Signup and view all the answers

What is the main function of cilia in the nasal cavity and lower respiratory airways?

<p>To move mucus and trapped particles toward the pharynx (B)</p> Signup and view all the answers

In the uterine tubes, what is the primary action facilitated by ciliary movement?

<p>Transportation of fluid toward the uterine cavity (B)</p> Signup and view all the answers

Which two factors are necessary for the proper movement of cilia?

<p>ATP and appropriate ionic conditions (B)</p> Signup and view all the answers

What is the role of genes in the cell nucleus?

<p>Control the synthesis of ribonucleic acid (RNA) (A)</p> Signup and view all the answers

What does the process termed 'gene expression' encompass?

<p>Transcription of genetic code and translation into proteins (C)</p> Signup and view all the answers

Which component is NOT part of the structure of a nucleotide?

<p>Amino acids (B)</p> Signup and view all the answers

How are nucleotides arranged to create DNA?

<p>In a double-stranded helical structure loosely bound to each other (B)</p> Signup and view all the answers

What is the total number of genes approximately found in each human cell?

<p>30,000 (C)</p> Signup and view all the answers

What are the components of the backbone of each DNA strand?

<p>Phosphoric acid and deoxyribose molecules (A)</p> Signup and view all the answers

Which purine base pairs with the pyrimidine base thymine?

<p>Adenine (B)</p> Signup and view all the answers

What is a code word in a DNA strand?

<p>A group of three successive bases (B)</p> Signup and view all the answers

What process allows DNA to control chemical reactions in the cytoplasm?

<p>Transcription (B)</p> Signup and view all the answers

What is the function of the RNA that is formed from DNA?

<p>It acts as a template for protein synthesis. (A)</p> Signup and view all the answers

Which of the following base pairs constitute a bond in DNA?

<p>Guanine with Cytosine (C)</p> Signup and view all the answers

What is the genetic code made up of?

<p>A sequence of nucleotide triplets (A)</p> Signup and view all the answers

In the cell nucleus, DNA is directly involved in the process of:

<p>RNA formation (C)</p> Signup and view all the answers

Flashcards

Medical Physiology Textbook

A book providing a detailed explanation of the function of the human body at a cellular and organ level.

Pocket Companion

A concise, portable summary of essential information from a larger medical textbook.

Copyright

Legal right granted to the creator of a work to control its use and distribution.

Permission to Reproduce

Formal authorization to copy or distribute content, essential for legal use.

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Citation Rules

Formal guidelines specifying how to properly reference or acknowledge the source of information.

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Publisher's Website

The official website of the publishing company that provides information on copyrights, permissions, and related policies.

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Educational Responsibility

Duty to use information responsibly for safe and ethical practices when applying knowledge.

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Research Methods

Strategies used to gather information and data for study, testing, and analysis.

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Oxygen Average Normal Value

The average normal value for oxygen in the extracellular fluid is 40 mm Hg.

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Carbon Dioxide Average Normal Value

The average normal value for carbon dioxide in the extracellular fluid is 40 mm Hg.

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Sodium Ion Normal Range

The normal range for sodium ion in the extracellular fluid is 138-146 mmol/L.

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Potassium Ion Normal Range

The normal range for potassium ion in the extracellular fluid is 3.8-5.0 mmol/L.

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Calcium Ion Normal Range

The normal range for calcium ion in the extracellular fluid is 1.0-1.4 mmol/L.

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Chloride Ion Normal Range

The normal range for chloride ion in the extracellular fluid is 103-112 mmol/L.

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Bicarbonate Ion Normal Range

The normal range for bicarbonate ion in the extracellular fluid is 24-32 mmol/L.

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Body Temperature Normal Range

The normal range for body temperature is 98-98.8 F (37.0 C).

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Smooth ER function

The smooth endoplasmic reticulum (ER) synthesizes lipids and carries out other intracellular processes aided by enzymes.

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Golgi Apparatus's role

The Golgi apparatus processes substances from the Endoplasmic Reticulum into lysosomes, secretory vesicles, and other cell components.

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ER vesicles function

Transport substances from ER to Golgi apparatus.

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Lysosome function

Lysosomes break down intracellular substances, including damaged cells, food particles & unwanted material.

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Lysosome membrane

Membranes keep lysosomal enzymes from causing damage to the cell.

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Mitochondria energy production

Mitochondria release energy through the chemical reaction of oxygen with food molecules (glucose, fatty acids, amino acids).

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Citric acid cycle

Enzymes in the mitochondria remove carbon dioxide and hydrogen ions from food molecules.

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Protein synthesis

mRNA works with ribosomes in the ER to synthesize proteins.

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ATP Formation

ATP is created through the recombination of ADP and phosphoric acid, powered by energy from cell nutrients. The process happens repeatedly.

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Mitochondrial ATP Production

Most ATP is made inside mitochondria using energy from the breakdown of nutrients.

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Glycolysis

The process of converting glucose to pyruvic acid in the cytoplasm.

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Acetyl-CoA

A molecule formed from carbohydrate, lipid, and protein breakdown that enters the citric acid cycle.

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Citric Acid Cycle (Krebs Cycle)

Chemical reactions that break down acetyl-CoA into hydrogen ions and carbon dioxide while releasing energy.

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Chemiosmotic Mechanism

The overall process of ATP production, involving hydrogen ion movement and ATP synthetase.

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ATP Synthetase

Globular proteins within the mitochondrial membrane that use hydrogen ion movement to produce ATP.

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Cellular Functions of ATP

ATP powers processes like membrane transport, chemical synthesis, and mechanical work in cells.

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DNA Backbone

The structure of a DNA strand, consisting of alternating phosphate groups and deoxyribose sugar molecules.

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DNA Bases

The four nitrogen-containing molecules (adenine, guanine, cytosine, and thymine) that attach to the sugar-phosphate backbone of DNA, forming the genetic code.

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Base Pairing Rules

Specific bonding between adenine (A) with thymine (T) and guanine (G) with cytosine (C) in DNA.

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DNA Code Word

A sequence of three consecutive bases in DNA that specifies a particular amino acid.

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Genetic Code

The complete set of DNA code words that determines the sequence of amino acids in a protein.

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Transcription

The process of copying genetic information from DNA into RNA in the nucleus.

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RNA

A single-stranded nucleic acid that carries genetic information from DNA in the nucleus to the ribosomes in the cytoplasm.

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Translation

The process of using RNA to synthesize proteins in the cytoplasm.

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Ciliary Movement

The whiplike motion of cilia in the nasal cavity and respiratory airways, moving mucus toward the pharynx to clear passageways.

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Cilia in Uterine Tubes

Cilia in the uterine tubes move fluid from the tube's opening toward the uterus, helping transport an ovum.

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ATP and Ions for Cilia

Ciliary movement requires ATP energy and specific ion concentrations, including magnesium and calcium.

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Genes Control Protein Synthesis

Genes in the cell nucleus contain the instructions for creating specific proteins, which control cellular function.

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Proteins: Enzymes and Structure

Proteins play a vital role in cells as enzymes that catalyze reactions and as building blocks for cellular structures.

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DNA Structure

DNA is composed of two long, helical strands, each made of nucleotides. Each nucleotide consists of a phosphate group, deoxyribose sugar, and one of four nitrogenous bases: adenine, guanine, thymine, and cytosine.

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Nucleotide Formation

A nucleotide forms when a phosphate group, a deoxyribose sugar molecule, and one of the four nitrogenous bases combine.

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DNA Strand Formation

Multiple nucleotides bind together to create two strands of DNA, which are then loosely connected to each other.

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Study Notes

Extracellular Fluid Constituents and Limits

  • Oxygen: Average: 40 mm Hg; Normal range: 35-45 mm Hg; Nonlethal limit: 10-1000 mm Hg
  • Carbon dioxide: Average: 40 mm Hg; Normal range: 35-45 mm Hg; Nonlethal limit: 5-80 mm Hg
  • Sodium ion: Average: 142 mmol/L; Normal range: 138-146 mmol/L; Nonlethal limit: 115-175 mmol/L
  • Potassium ion: Average: 4.2 mmol/L; Normal range: 3.8-5.0 mmol/L; Nonlethal limit: 1.5-9.0 mmol/L
  • Calcium ion: Average: 1.2 mmol/L; Normal range: 1.0-1.4 mmol/L; Nonlethal limit: 0.5-2.0 mmol/L
  • Chloride ion: Average: 108 mmol/L; Normal range: 103-112 mmol/L; Nonlethal limit: 70-130 mmol/L
  • Bicarbonate ion: Average: 28 mmol/L; Normal range: 24-32 mmol/L; Nonlethal limit: 8-45 mmol/L
  • Glucose: Average: 85 mg/dL; Normal range: 75-95 mg/dL; Nonlethal limit: 20-1500 mg/dL
  • Body temperature: Average: 98.4°F (37.0°C); Normal range: 98-98.8°F (37.0°C); Nonlethal limit: 65-110°F (18.3-43.3°C)
  • Acid-base (pH): Average: 7.4; Normal range: 7.3-7.5; Nonlethal limit: 6.9-8.0

Cell Structure and Function

  • Endoplasmic Reticulum (ER): Involved in protein synthesis, lipid synthesis and modification. Two types: rough (with ribosomes) and smooth (agranular).
  • Golgi Apparatus: Processes substances from the ER, modifies and packages them into lysosomes, secretory vesicles, other cellular components.
  • Lysosomes: Contain digestive enzymes, break down intracellular substances (damaged cells, food particles, bacteria). Membranes protect them from damaging cell contents.
  • Mitochondria: Release energy via oxidation of foods (carbohydrates, fats, proteins). Crucial for ATP formation from ADP.
  • ATP Formation: Main pathway occurs in the mitochondria: foods are broken down, hydrogen ions combine with oxygen (releasing energy), energy used to convert ADP to ATP. Process called the chemiosmotic mechanism.
  • ATP Usage: ATP fuels cellular processes; membrane transport (sodium-potassium pump), synthesis, and mechanical work (muscle contraction).
  • Cilia: Whiplike structures, involved in movement of mucus (respiratory system), and fluid (uterine tubes). Require ATP and specific ionic conditions (magnesium, calcium).

Genetic Control of Protein Synthesis

  • Gene Function: Genes (DNA) control protein synthesis and therefore cell function via the process of gene expression.
  • DNA Structure: Double-stranded helix composed of nucleotides with phosphoric acid, deoxyribose sugar, nitrogenous bases.
  • DNA Code: Organized as triplets of bases forming code words. A unique code word determines the sequence of amino acids in the resultant protein.
  • Transcription: Process where DNA code is copied to RNA code (which moves to the cytoplasm). RNA needs proteins and proper ionic environment for the synthesis.
  • Figure 3–1: Demonstrates the process by which genes in the nucleus control cell function in the cytoplasm. RNA is transcribed from the DNA and translated to proteins in the cytoplasm.

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