Exploring Cytochrome P450 Enzymes and Genetic Polymorphism in Drug Metabolism
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Questions and Answers

Which factor is the main focus in pharmacokinetic variability?

  • Polymorphism
  • Variability in drug metabolism (correct)
  • Enzyme activity
  • Genetic make up

    • Which term refers to the genetic variation or occurrence of different forms among a group of organisms or species?

  • Polymorphism (correct)
  • Genetic make up
  • Variability
  • Enzyme activity

    • What is the dependency of enzyme activity and availability?

  • Polymorphism
  • Variability in drug metabolism
  • Pharmacokinetic variability
  • Genetic make up (correct)

    • Which of the following can occur if there is a deficiency of certain enzymes?

    <p>Increased plasma concentration of the corresponding drug substrate</p> Signup and view all the answers

    What is the potential consequence of increased plasma concentration of a drug substrate?

    <p>Decreased drug efficacy</p> Signup and view all the answers

    What is the relationship between enzyme deficiency and adverse drug effects?

    <p>Enzyme deficiency can increase the incidence of adverse drug effects</p> Signup and view all the answers

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