Exploring Cytochrome P450 Enzymes and Genetic Polymorphism in Drug Metabolism

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6 Questions

Which factor is the main focus in pharmacokinetic variability?

Variability in drug metabolism

Which term refers to the genetic variation or occurrence of different forms among a group of organisms or species?

Polymorphism

What is the dependency of enzyme activity and availability?

Genetic make up

Which of the following can occur if there is a deficiency of certain enzymes?

Increased plasma concentration of the corresponding drug substrate

What is the potential consequence of increased plasma concentration of a drug substrate?

Decreased drug efficacy

What is the relationship between enzyme deficiency and adverse drug effects?

Enzyme deficiency can increase the incidence of adverse drug effects

Test your knowledge on cytochrome p450 enzymes and genetic polymorphism in drug metabolism. This quiz will assess your understanding of the variability in enzyme expression and its impact on pharmacokinetics.

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