PATH L1C | Exocrine Pancreas Pathologies
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Questions and Answers

What is the most common congenital anomaly of the pancreas?

  • Pancreatic pseudocyst
  • Cystic fibrosis
  • Pancreatic adenocarcinoma
  • Pancreas divisum (correct)

    • What is the incidence of pancreas divisum?

  • 10% to 15%
  • 3% to 10% (correct)
  • 20% to 25%
  • 1% to 5%

    • What causes pancreas divisum?

  • Failure of fusion of the fetal duct systems of the dorsal and ventral pancreatic primordia (correct)
  • Inflammation of the pancreas
  • Blockage of the pancreatic ducts
  • Excessive production of digestive enzymes

    • What percentage of individuals with pancreas divisum are asymptomatic?

    <p>95%</p> Signup and view all the answers

    What is the main cause of acute or chronic pancreatitis in individuals with pancreas divisum?

    <p>Inadequate drainage of pancreatic secretions through the minor papilla</p> Signup and view all the answers

    Which duct drains only a small portion of the head of the gland through the papilla of Vater in individuals with pancreas divisum?

    <p>The duct of Wirsung</p> Signup and view all the answers

    Which of the following is a common cause of acute pancreatitis in the United States?

    <p>Gallstones impaction</p> Signup and view all the answers

    What is the approximate overall mortality rate for acute pancreatitis?

    <p>5%</p> Signup and view all the answers

    What is the estimated annual incidence of acute pancreatitis globally?

    <p>33 to 74 per 100,000</p> Signup and view all the answers

    What is the most common cause of chronic pancreatitis?

    <p>Chronic excessive alcohol consumption</p> Signup and view all the answers

    What is the prevalence range of chronic pancreatitis in the U.S. population?

    <p>1% to 5%</p> Signup and view all the answers

    What is the approximate 5-year survival rate for pancreatic carcinoma?

    <p>8%</p> Signup and view all the answers

    What are the most common antecedent lesions of pancreatic cancer called?

    <p>Pancreatic intraepithelial neoplasias (PanINs)</p> Signup and view all the answers

    What role does aberrant function of the cystic fibrosis transmembrane conductance regulator (CFTR) play in pancreatic disease?

    <p>It affects the biochemical content and viscosity of pancreatic secretions</p> Signup and view all the answers

    What are the most common cause of acute pancreatitis and chronic pancreatitis respectively?

    <p>Gallstones, alcohol</p> Signup and view all the answers

    Which gene mutations are often found to be mutated in familial acute pancreatitis?

    <p>PRRS1, SPINK1</p> Signup and view all the answers

    What is the female-to-male ratio for serous cystadenomas?

    <p>2 : 1</p> Signup and view all the answers

    What percentage of all pancreatic cysts are neoplastic?

    <p>5% to 15%</p> Signup and view all the answers

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