PHYSIO L5C | Exocrine Pancreas GI

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Questions and Answers

What is the main function of the pancreas?

  • Producing and secreting digestion proteins
  • Synthesizing and secreting large quantities of protein
  • Completing the intraluminal digestion of ingested carbohydrates, protein, and fat (correct)
  • Neutralizing the acidic gastric contents

What is the morphology of the secretory unit in the pancreas?

  • Cluster of acinar cells
  • Main pancreatic duct
  • Intralobular ducts
  • Acinus and an intercalated duct (correct)

What are the special histological features of the pancreatic acinar cells?

  • Synthesizing and secreting large quantities of protein
  • Polarized epithelial cells specialized for the production and export of proteins (correct)
  • Cluster of acinar cells that synthesize and secrete proteins
  • Specialized for the production and export of large quantities of protein

What is the location of the pancreas within the body?

<p>Retroperitoneal organ (C)</p> Signup and view all the answers

How do intercalated ducts merge to form the main pancreatic duct?

<p>By merging to form interlobular ducts first (B)</p> Signup and view all the answers

What is the specialization of acinar cells in the pancreas?

<p>Producing and exporting large quantities of protein (C)</p> Signup and view all the answers

Which of the following best describes the secretory granules of pancreatic acinar cells?

<p>Contain zymogens and enzymes required for digestion (A)</p> Signup and view all the answers

What is the most characteristic feature of the acinar cell?

<p>Abundance of electron-dense secretory granules at the apical pole (B)</p> Signup and view all the answers

What stimulates HCO3 secretion by the pancreatic duct?

<p>Secretin (D)</p> Signup and view all the answers

How does secretin stimulate HCO3 secretion by the pancreatic duct?

<p>Stimulating adenylyl cyclase and raising cAMP levels (D)</p> Signup and view all the answers

What physiological mediator stimulates pancreatic protein secretion?

<p>Cholecystokinin (CCK) (B)</p> Signup and view all the answers

How does CCK stimulate enzyme secretion through a CCK 1 receptor on the acinar cell?

<p>By stimulating adenylyl cyclase and raising cAMP levels (B)</p> Signup and view all the answers

What do pancreatic juices contain that is responsible for digestion?

<p>Bicarbonate and chloride ions (C)</p> Signup and view all the answers

What happens to pancreatic flow rate at high flow rates?

<p>$Na^+$ and $HCO_3^-$ become the main components of pancreatic fluid (B)</p> Signup and view all the answers

What is the most characteristic feature of the acinar cell?

<p>Abundance of electron-dense secretory granules (B)</p> Signup and view all the answers

In which pancreatic cells can we find the CFTR regulator?

<p>Apical membrane of pancreatic duct cells (C)</p> Signup and view all the answers

What stimulates adenylyl cyclase in the duct cells?

<p>Secretin (A)</p> Signup and view all the answers

Which physiological mediator stimulates pancreatic protein secretion?

<p>Cholecystokinin (B)</p> Signup and view all the answers

What is the main function of the pancreatic duct cells?

<p>Fluid and electrolyte transport (A)</p> Signup and view all the answers

Which hormone stimulates HCO3 secretion by the pancreatic duct?

<p>Secretin (C)</p> Signup and view all the answers

What are the secretory proteins responsible for digestion?

<p>$Proteases$, $Amylases$, and $Lipases$ (D)</p> Signup and view all the answers

What are the two pathways through which CCK stimulates enzyme secretion?

<p>$Direct$ and $Indirect$ pathways (C)</p> Signup and view all the answers

$CFTR$ channel activation stimulates what type of ion transport in pancreatic duct cells?

<p>$Cl^-$ secretion (C)</p> Signup and view all the answers

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