PHYSIO L5C | Exocrine Pancreas GI
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Questions and Answers

What is the main function of the pancreas?

  • Producing and secreting digestion proteins
  • Synthesizing and secreting large quantities of protein
  • Completing the intraluminal digestion of ingested carbohydrates, protein, and fat (correct)
  • Neutralizing the acidic gastric contents

    • What is the morphology of the secretory unit in the pancreas?

  • Cluster of acinar cells
  • Main pancreatic duct
  • Intralobular ducts
  • Acinus and an intercalated duct (correct)

    • What are the special histological features of the pancreatic acinar cells?

  • Synthesizing and secreting large quantities of protein
  • Polarized epithelial cells specialized for the production and export of proteins (correct)
  • Cluster of acinar cells that synthesize and secrete proteins
  • Specialized for the production and export of large quantities of protein

    • What is the location of the pancreas within the body?

    <p>Retroperitoneal organ</p> Signup and view all the answers

    How do intercalated ducts merge to form the main pancreatic duct?

    <p>By merging to form interlobular ducts first</p> Signup and view all the answers

    What is the specialization of acinar cells in the pancreas?

    <p>Producing and exporting large quantities of protein</p> Signup and view all the answers

    Which of the following best describes the secretory granules of pancreatic acinar cells?

    <p>Contain zymogens and enzymes required for digestion</p> Signup and view all the answers

    What is the most characteristic feature of the acinar cell?

    <p>Abundance of electron-dense secretory granules at the apical pole</p> Signup and view all the answers

    What stimulates HCO3 secretion by the pancreatic duct?

    <p>Secretin</p> Signup and view all the answers

    How does secretin stimulate HCO3 secretion by the pancreatic duct?

    <p>Stimulating adenylyl cyclase and raising cAMP levels</p> Signup and view all the answers

    What physiological mediator stimulates pancreatic protein secretion?

    <p>Cholecystokinin (CCK)</p> Signup and view all the answers

    How does CCK stimulate enzyme secretion through a CCK 1 receptor on the acinar cell?

    <p>By stimulating adenylyl cyclase and raising cAMP levels</p> Signup and view all the answers

    What do pancreatic juices contain that is responsible for digestion?

    <p>Bicarbonate and chloride ions</p> Signup and view all the answers

    What happens to pancreatic flow rate at high flow rates?

    <p>$Na^+$ and $HCO_3^-$ become the main components of pancreatic fluid</p> Signup and view all the answers

    What is the most characteristic feature of the acinar cell?

    <p>Abundance of electron-dense secretory granules</p> Signup and view all the answers

    In which pancreatic cells can we find the CFTR regulator?

    <p>Apical membrane of pancreatic duct cells</p> Signup and view all the answers

    What stimulates adenylyl cyclase in the duct cells?

    <p>Secretin</p> Signup and view all the answers

    Which physiological mediator stimulates pancreatic protein secretion?

    <p>Cholecystokinin</p> Signup and view all the answers

    What is the main function of the pancreatic duct cells?

    <p>Fluid and electrolyte transport</p> Signup and view all the answers

    Which hormone stimulates HCO3 secretion by the pancreatic duct?

    <p>Secretin</p> Signup and view all the answers

    What are the secretory proteins responsible for digestion?

    <p>$Proteases$, $Amylases$, and $Lipases$</p> Signup and view all the answers

    What are the two pathways through which CCK stimulates enzyme secretion?

    <p>$Direct$ and $Indirect$ pathways</p> Signup and view all the answers

    $CFTR$ channel activation stimulates what type of ion transport in pancreatic duct cells?

    <p>$Cl^-$ secretion</p> Signup and view all the answers

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