23 Questions
What is the main function of the pancreas?
Completing the intraluminal digestion of ingested carbohydrates, protein, and fat
What is the morphology of the secretory unit in the pancreas?
Acinus and an intercalated duct
What are the special histological features of the pancreatic acinar cells?
Polarized epithelial cells specialized for the production and export of proteins
What is the location of the pancreas within the body?
Retroperitoneal organ
How do intercalated ducts merge to form the main pancreatic duct?
By merging to form interlobular ducts first
What is the specialization of acinar cells in the pancreas?
Producing and exporting large quantities of protein
Which of the following best describes the secretory granules of pancreatic acinar cells?
Contain zymogens and enzymes required for digestion
What is the most characteristic feature of the acinar cell?
Abundance of electron-dense secretory granules at the apical pole
What stimulates HCO3 secretion by the pancreatic duct?
Secretin
How does secretin stimulate HCO3 secretion by the pancreatic duct?
Stimulating adenylyl cyclase and raising cAMP levels
What physiological mediator stimulates pancreatic protein secretion?
Cholecystokinin (CCK)
How does CCK stimulate enzyme secretion through a CCK 1 receptor on the acinar cell?
By stimulating adenylyl cyclase and raising cAMP levels
What do pancreatic juices contain that is responsible for digestion?
Bicarbonate and chloride ions
What happens to pancreatic flow rate at high flow rates?
$Na^+$ and $HCO_3^-$ become the main components of pancreatic fluid
What is the most characteristic feature of the acinar cell?
Abundance of electron-dense secretory granules
In which pancreatic cells can we find the CFTR regulator?
Apical membrane of pancreatic duct cells
What stimulates adenylyl cyclase in the duct cells?
Secretin
Which physiological mediator stimulates pancreatic protein secretion?
Cholecystokinin
What is the main function of the pancreatic duct cells?
Fluid and electrolyte transport
Which hormone stimulates HCO3 secretion by the pancreatic duct?
Secretin
What are the secretory proteins responsible for digestion?
$Proteases$, $Amylases$, and $Lipases$
What are the two pathways through which CCK stimulates enzyme secretion?
$Direct$ and $Indirect$ pathways
$CFTR$ channel activation stimulates what type of ion transport in pancreatic duct cells?
$Cl^-$ secretion
Test your knowledge about the anatomy and function of the exocrine pancreas. Learn about the general characteristics, histological features, protein secretion, regulation of pancreatic secretion, and duct cells.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
