Exercise & Diving: ECG and Nervous System

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Questions and Answers

During exercise, the decrease in pulse amplitude is primarily attributed to:

  • Selective vasoconstriction shunting blood towards actively engaged muscle groups. (correct)
  • A generalized increase in blood flow across all tissues, lowering perceived pressure.
  • Increased venous return leading to a reduction in cardiac preload and stroke volume.
  • Vasodilation in non-exercising muscle groups to reduce overall peripheral resistance.

During the diving simulation, the release of norepinephrine, binding to S.A node cells, is the primary driver of the observed decrease in heart rate.

False (B)

Exercise induces an increase in heart rate primarily due to the release of _______________, which subsequently binds to the S.A. node cells of the heart.

norepinephrine

Explain the biophysical mechanism through which baroreceptors mediate the release of acetylcholine during a diving simulation, ultimately affecting heart rate.

<p>Baroreceptors detect high blood pressure, which triggers the release of acetylcholine. Acetylcholine binds to muscarinic receptors on the S.A. node cells (pacemaker cells) in the heart, increasing potassium permeability and hyperpolarizing the cell membrane. This process slows the rate of depolarization, reducing heart rate.</p> Signup and view all the answers

Match the physiological response to the compensatory mechanism during the diving simulation:

<p>Decreased pulse amplitude = Vasoconstriction Decreased heart rate = Acetylcholine release Increased central blood flow = Blood shunting to vital organs</p> Signup and view all the answers

In the context of post-exercise recovery, the restoration of heart rate to normal levels is primarily due to:

<p>The cessation of norepinephrine release, re-establishing baseline sympathetic activity. (C)</p> Signup and view all the answers

Following the diving simulation, the primary mechanism for restoring oxygen balance in peripheral tissues involves an immediate and unrestricted increase in blood supply to these previously deprived areas.

<p>False (B)</p> Signup and view all the answers

During recovery from exercise, the increase in pulse amplitude is attributed to the restoration of blood flow to tissues previously ________________ during exercise.

<p>undersupplied</p> Signup and view all the answers

Explain the physiological feedback loop that governs the adjustment of blood flow to peripheral tissues both during exercise and in the subsequent recovery period.

<p>During exercise, baroreceptors and chemoreceptors detect changes in blood pressure and oxygen levels. This triggers vasoconstriction and shunting of blood to active muscle groups, simultaneously reducing flow to less essential tissues. Post-exercise, as metabolic demands decrease and oxygen levels normalize, vasodilation occurs in previously constricted vessels. The cessation of norepinephrine allows blood flow to redistribute to the tissues that were previously under-supplied, restoring homeostasis.</p> Signup and view all the answers

Match the phase of physiological response with its corresponding cardiovascular effect.

<p>Exercise = Increased heart rate, decreased pulse amplitude Diving Simulation = Decreased heart rate, decreased pulse amplitude Recovery (post-dive) = Restoration of heart rate and pulse amplitude to resting levels</p> Signup and view all the answers

The primary determinant for the increase in tidal volume observed after exercise is:

<p>The need to expel increased carbon dioxide produced during exercise. (C)</p> Signup and view all the answers

An increase in expiratory reserve volume (ERV) contributes to the observed increase in tidal volume following exercise.

<p>False (B)</p> Signup and view all the answers

In the calculation TLC - VC = estimated _______________ volume, the formula estimates the air remaining in the lungs after maximal exhalation.

<p>residual</p> Signup and view all the answers

Using a quantitative approach, illustrate how the dynamic changes in tidal, inspiratory reserve, and expiratory reserve volumes collaborate to enhance pulmonary ventilation following a bout of intense exercise.

<p>Increase in tidal volume occurs because as we exercise we create more CO2 that needs to exit the body. This will increase the tidal volume, by tapping into reserves of the IRV and ERV (consequently decreasing both). The magnitude of this enhancement depends on several factors, including exercise intensity, individual fitness level, and pre-existing respiratory conditions. It results in ventilation increasing above normal amount.</p> Signup and view all the answers

Match the lung volume/capacity with its expected change following exercise:

<p>Tidal Volume = Increase Inspiratory Reserve Volume = Decrease Expiratory Reserve Volume = Decrease Vital Capacity = Decrease</p> Signup and view all the answers

In biological terms, why do males generally exhibit larger lung capacities compared to females?

<p>Greater body mass, tissue volume, and oxygen demand associated with larger size. (C)</p> Signup and view all the answers

Predicted vital capacity based on age, height, and sex alone is a completely accurate reflection of measured vital capacity.

<p>False (B)</p> Signup and view all the answers

Increased lung parameters in males are primarily linked to a higher requirement for ___________, due to increased lung size, tissue mass, and cellularity.

<p>oxygen</p> Signup and view all the answers

Assess the limitations of predicting vital capacity using only age, height, and sex, and propose additional physiological parameters that could improve the accuracy of the estimated value.

<p>The prediction of vital capacity based solely on age, height, and sex omits critical factors such as: activity level, smoking history, weight, certain races and other medical conditions. Including additional physiological parameters such as respiratory muscle strength, body composition, and underlying health conditions could significantly refine the estimation.</p> Signup and view all the answers

Match the physiological factor with its related influence on lung capacity:

<p>Body Size = Directly proportional to lung capacity Sex = Males typically have larger lung capacities Age = Can decrease lung capacity due to reduced elasticity</p> Signup and view all the answers

When a worm is placed in a hypertonic solution, the resulting crenation is biophysically driven by:

<p>Osmotic movement of water out of the worm, leading to cellular shrinkage. (D)</p> Signup and view all the answers

If a worm with tissue osmolarity of 300 mOsm is placed in a 20% seawater (approximately 400 mOsm) solution, it will be in a hypotonic environment, causing the worm to gain weight.

<p>False (B)</p> Signup and view all the answers

Hypertonic solutions cause cells to ____________, while hypotonic solutions cause cells to swell.

<p>shrink</p> Signup and view all the answers

Describe a detailed mechanism by which changes in osmolarity influence cell volume, including the roles of aquaporins, osmotic pressure gradients, and cellular membrane dynamics.

<p>Aquaporins, membrane-spanning proteins, function as highly selective water channels, facilitating rapid bidirectional water transport across the cell membrane. In hypertonic extracellular environments, a higher solute concentration outside the cell creates an osmotic imbalance. This osmotic pressure gradient drives water movement through aquaporins from the intracellular space (low solute concentration) to the extracellular space (high solute concentration). As water exits the cell, the cell volume decreases—a process referred to as crenation or shrinkage. The cell membrane responds by folding or shrinking to accommodate the reduced cell volume. Conversely, in hypotonic extracellular environments, the higher solute concentration inside the cell draws water inward through aquaporins, leading to cell swelling and potentially lysis if unchecked by regulatory mechanisms.</p> Signup and view all the answers

Match the solution tonicity with the expected cellular response:

<p>Isotonic = No Change in Cell Volume Hypertonic = Cell Shrinkage Hypotonic = Cell Swelling</p> Signup and view all the answers

In an isotonic solution, red blood cells maintain a biconcave shape primarily due to:

<p>Equilibrium in water movement across the cell membrane, preserving cell volume. (B)</p> Signup and view all the answers

In a hypotonic solution, the RBC diameter decreases as water moves out of the cell, causing it to shrink.

<p>False (B)</p> Signup and view all the answers

In a hypertonic solution, water moves _________ of the RBCs causing the cells to shrink.

<p>out</p> Signup and view all the answers

Provide a detailed biophysical explanation of why RBCs swell and can potentially lyse in a hypotonic solution, incorporating principles of osmotic pressure, membrane tensile strength, and regulatory mechanisms.

<p>In a hypotonic environment, the concentration of water outside the cell is greater than that inside the cell. This creates a water potential gradient that favors the movement of water from the extracellular fluid, across the semi-permeable cell membrane, and into the RBC cytoplasm through aquaporins. As water influx exceeds efflux, the intracellular volume gradually increases. Ultimately, the cell expands beyond its inherent tensile strength, leading to membrane rupture and cellular lysis.</p> Signup and view all the answers

Match the solution type with the corresponding change in RBC diameter.

<p>Hypotonic = Increase in RBC diameter Hypertonic = Decrease in RBC diameter. Isotonic = No change to RBC Diameter</p> Signup and view all the answers

An increase in the mass of an animal is directly proportional to an increase in its metabolic rate due to:

<p>The greater quantity of tissue requiring more energy and oxygen for maintenance. (C)</p> Signup and view all the answers

In larger animals, cellular respiration occurs less within the body, leading to lower carbon dioxide production and reduced need for metabolic rate increase.

<p>False (B)</p> Signup and view all the answers

As mass increases, the metabolic rate typically ___________ as well due to the heightened need for energy and oxygen.

<p>increases</p> Signup and view all the answers

Explain the complex relationship between body mass, surface area to volume ratio, and metabolic rate. Include a discussion of how these factors impact heat dissipation across organisms of varying sizes.

<p>An increase in animal size (and thus mass) is associated with a decrease in surface area to volume ratio. Metabolic heat production is related to volume. Since mass increases at a much greater rate than surface area (volume increases with the cube of the radius, while surface area increases by the square of the radius), larger animals produce more heat than they can dissipate through their external surface. As a result of all this, larger animals tend to have lower mass-specific metabolic rates.</p> Signup and view all the answers

Match aspects of body size with the function.

<p>Metabolic Rate = Related proportionally to Mass Surface Area to Volume Ratio = Decreases with size (Less Heat Loss) Tissue Oxygen Demand = Requires increase with mass</p> Signup and view all the answers

Temperature increase is expected to increase metabolic rate until:

<p>Temperature is too low or too high, which cause enzymes to slow down or become denatured, which prevent chemical reactions from happening. (C)</p> Signup and view all the answers

If Q10 is around 2 this means that the metabolic rate has decreased by half.

<p>False (B)</p> Signup and view all the answers

The Q10 calculation gives us a measurement of metabolic rate at high temperature divided by the metabolic rate at a temperature _______ degrees lower.

<p>10</p> Signup and view all the answers

Discuss the mechanism that links enzymes and temperature.

<p>Mealworms are ectotherms meaning they are dependent on the temp. of the environment around them. Temperature adjustment will affect glycolysis and the TCA cycle. This is because they are dependent and catalyzed by enzymes. Enzymes allow a process to happen more rapidly by lowering the activation energy needed. Enzyme function changes with temperature, therefore changing the rate of a reaction or chemical process. Higher temperatures = faster metabolic rate. Lower temperatures = lower metabolic rate. However too cold or too hot of temps can denature enzymes, prohibiting chemical processes to occur.</p> Signup and view all the answers

Link the metabolic outcome with the temperature change.

<p>Temperature Increases = Metabolic Rate Increased Temperate Decreases = Metabolic Rate Decreased Temperature Too High = Enzymes Denature (Prohibiting Processes)</p> Signup and view all the answers

Flashcards

Exercise effects on heart rate and pulse amplitude

Exercise increases heart rate and decreases pulse amplitude.

Norepinephrine's effect on heart rate

Norepinephrine release increases heart rate by binding to S.A node cells.

Blood flow during exercise

Blood flow is redirected to active muscles requiring oxygen during exercise.

Post-exercise recovery

Heart rate and pulse amplitude return to normal after exercise.

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Diving simulation effects

Heart rate and pulse amplitude decrease during simulated diving.

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Vasoconstriction and Pulse Amplitude

Vasoconstriction causes a decrease in pulse amplitude.

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Acetylcholine in diving simulation

Acetylcholine release during diving simulation lowers heart rate.

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Vital organ blood flow during diving

Central blood flow increases to vital organs during diving to survive.

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Post-dive recovery

Heart rate and pulse amplitude return to resting levels post-dive, oxygen is supplied.

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Lung Parameters After Exercise

Tidal volume increases post-exercise, while IRV, ERV, and vital capacity decrease.

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CO2 and Tidal Volume

Exercise increases CO2, increasing tidal volume.

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Residual volume calculation

TLC - VC = estimated residual volume.

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Lung capacity differences

Males have larger lung capacities than females.

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Male Oxygen Needs

Increased lung size, tissues, and cells in males require more oxygen.

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Predicted vs Measured Vital Capacity

Predicted vital capacity should be greater than measured vital capacity.

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Vital Capacity Formula Limitations

The formula only accounts for age, height, and sex, and is not comprehensive.

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Worm Mass vs. Seawater Percent

As seawater percentage rises, worm mass decreases; as it falls, mass increases.

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Hypertonic vs. Hypotonic Solutions

Hypertonic solutions draw water out, hypotonic solutions make cells expand.

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RBC shape in different solutions

Isotonic: biconcave. Hypertonic: shrink. Hypotonic: swell.

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Metabolic Rate relation to mass

Mass increases, metabolic rate increases directly.

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Energy needs of larger animals

Larger animals need more energy, hence higher metabolism.

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Temperature and Metabolic Rate

Metabolic rate increases with temperature until enzymes denature.

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Ectotherms and Metabolism

Ectotherms adjust metabolically to temperature, affecting glycolysis and TCA.

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Q10 calculation

Q10 = metabolic rate at high temp/metabolic rate at temp 10 degrees lower

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Temperature on Pulse Amplitude

Heat increases pulse amplitude; cool down lowers it.

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Thermoreceptors and homeostasis

Thermoreceptors detect temp. changes, triggering vasodilation (heat loss) or vasoconstriction (heat retention).

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Arm position on pulse amplitude

Arm elevated, pulse amplitude decreases; arm lowered, it increases.

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Gravity on Blood Flow

Gravity affects blood flow, causing pooling or draining.

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Auditory vs. Visual Reaction Times

Auditory cues elicit faster responses than visual cues.

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shorter Auditory Pathway

Less complex auditory signal pathway result a fast response.

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Visuomotor Adaptation with Prism Goggles

With prism goggles on, early throws are displaced but later throws adjust. Removing them displaces again.

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Visuomotor Adaptation

Bodies adapt through visuo-motor learning.

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insect Metathoracic Leg sensory response

Leg movements respond in sensory neurons in the chordotonal organ

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chordotonal organ reaction to different angles

Afferent neuron sends more actions potentials with increase leg bend angles

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chordotonal Organ sensory adaptation

Phasic-tonic response- high initial firing frequency that then drops very quickly but doesnt hit zero

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relationship between grip force and EMG activity

As grip force increases, EMG activity will increase to max level

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Motor Units and Electrical Activity

As more motor units are involved, there is an increase in electrical activity.

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Quick reflex vs slow action

Reflex responses in short time, creating quick action

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Mechanosensory Receptors

Mechanosensory receptors, called muscle spindles enter and give reflex action

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Study Notes

Lab 7, Experiment 1: Exercise Effects on ECG and Peripheral Nervous System

  • Exercise leads to increased heart rate and decreased pulse amplitude compared to rest.
  • Norepinephrine release causes heart rate to increase via binding to S.A node cells, also known as pacemaker cells.
  • Pulse amplitude decreases because blood is directed to specific muscle groups needing oxygen during exercise.
  • During recovery, heart rate returns to normal as norepinephrine release ceases.
  • Pulse amplitude increases to pre-exercise levels as blood flow normalizes to tissues previously restricted.

Lab 7, Experiment 2: Heart Rate and Peripheral Blood Flow During Diving

  • During simulated diving, expect a decrease in both pulse amplitude and heart rate.
  • Pulse amplitude decreases due to vasoconstriction initiated by baroreceptors sensing high pressure and triggering release of acetylcholine.
  • Acetylcholine released decreases heart rate via binding to heart's pacemaker cells
  • Survival mode activates, increasing central blood flow toward vital organs like the brain and heart.
  • During recovery, heart rate and pulse amplitude return to resting levels as oxygen is supplied to tissues deprived during the dive.

Lab 6, Experiment 1: Lung Parameter Changes with Exercise

  • Lung parameters are expected to differ as a result of testing before and after exercise.
  • Expect to see an increase in tidal volume post-exercise.
  • There will be a decrease in inspiratory reserve volume, expiratory reserve volume, and vital capacity after exercise.
  • Increased CO2 production during exercise drives the need to increase tidal volume.
  • IRV and ERV reserves are tapped into, decreasing their values.
  • TLC - VC = Estimated residual volume.

Lab 6, Experiment 2: Lung Parameter Differences Between Sexes

  • Lung parameters differ based on being male or female.
  • Males should have larger lung capacities compared to females.
  • Males generally have increased lung size, tissues, and cells, creating a need for greater oxygen supply.

Lab 6, Experiment 3: Predicted vs. Measured Vital Capacity

  • Predicted vital capacity should be greater than measured vital capacity.
  • The formula used considers only age, height, and sex, so does not account for all factors.

Lab 5, Experiment 1: Mass Change vs. Seawater Percentage

  • Mass percentage change in worms shifts depending on surrounding seawater concentrations.
  • Mass decreases with increasing seawater percentage.
  • Mass increases occur as seawater percentage decreases.
  • Worm tissues contain 250-400 milliosmolar tissues, so 25-40% is hypertonic.
  • Weight changes because water moves in or out of worm tissues.
  • Hypertonic solutions draw water out of the worm (low to high solute concentration), causing crenation and water loss.
  • Hypotonic solutions cause water to move into the worm's cells (higher solute concentration), leading to cell expansion and water gain.
  • Mass > 100 = weight gain and Mass < 100 = weight loss

Lab 5, Experiment 2: RBC Diameter vs. Treatment Solutions

  • Exposure to different treatment solutions shows changes in RBC diameter .
  • RBCs maintain a biconcave shape in isotonic solutions due to osmotic equilibrium.
  • RBC diameter decreases in hypertonic solutions due to water moving out, resulting in cell shrinkage.
  • RBC diameter increases in hypotonic solutions due to water moving in, causing swelling and a more spherical shape.
  • Hypo- results in increased diameter (swell)
  • Hyper- results in decreased diameter (shrink)

Lab 8, Experiment 1: Mass vs. Metabolic Rate

  • Mass relates to metabolic rate.
  • As mass increases, metabolic rate increases.
  • Larger animals have an increased amount of tissues to supply
  • Metabolic Rate is directly proportional to mass.
  • Larger animals have more tissues, driving them to be dependent on higher energy (oxygen) which increases cellular respiration increasing carbon dioxide that needs to be burned off.

Lab 8, Experiment 2: Temperature's Effect on Metabolic Rate

  • Metabolic rate varies to temperature.
  • Metabolic rate increases when temperature increases but decreases when temperature decreases.
  • Mealworms are ectotherms, therefore their temperature depends on the surrounding environment.
  • Temperature affects glycolysis and the TCA cycle because they depend on enzymes and their catalysis.
  • Enzymes speed up processes by lowering activation energy.
  • Enzyme function changes with temperature, which changes the rate of reactions in general.
  • Higher temperatures equate to faster metabolic rates.
  • Lower temperatures equate to slower metabolic rates.
  • Temperatures too high or too low can cause enzyme denaturing.
  • Q10 = metabolic rate at high temp/ metabolic rate at 10 degrees lower
  • Q10 should be around 2. 2 represents an increase in metabolic rate (associated with enzyme activity).

Lab 1, Experiment 1: Pulse Amplitude vs. Temperature

  • Average pulse amplitude (peripheral blood flow) changes based on temperature treatments.
  • Heat treatment should increase average pulse amplitude compared to at rest.
  • Pulse amplitude should begin to return back to normal during cool down.
  • Thermoreceptors in the skin detect temperature changes and signal the hypothalamus to initiate a response.
  • Vasodilation (relaxation) occurs in response to heat to release excess heat.
  • Vasoconstriction occurs in response to cold temperatures to prevent heat from escaping.
  • Increase in blood flow = increase in pulse amplitude (Get rid of heat)
  • Decrease in blood flow = decrease in pulse amplitude (Keep heat in)

Lab 1, Experiment 2: Gravity and Peripheral Blood Flow

  • Gravity's effect on peripheral flow is noted in this experiment.
  • When the arm is elevated, pulse amplitude decreases compared to resting.
  • When the arm is lowered, pulse amplitude increases compared to resting.
  • Arm elevated leads to draining (less blood being supplied to the capillaries)
  • Arm lowered leads to ‘pooling' (more blood being supplied to the capillaries);
  • Gravitational force has an effect on the body and circulatory system.

Lab 2, Experiment 1: Reaction Times to Auditory and Visual Cues

  • Reaction times vary between auditory and visual cues.
  • Individuals respond faster to auditory cues compared to visual cues.
  • Auditory pathway is shorter than the visual pathway, so the body responds quicker.
  • Auditory system: sound waves → sensory hair cells (triggers AP).
  • Visual system: photoreceptors → network of neurons → initial integration → processing of information → neurotransmitters involved.
  • Complexity indicates that longer time is needed to respond.

Lab 2, Experiment 2: Throwing Displacement with Prism Goggles

  • The average horizontal displacement with throwing varies depending on if prism goggles are being worn.
  • Early throws with goggles show greater horizontal displacement because the body has not fully adapted.
  • As throws continue, accuracy increases.
  • Removing goggles leads to displacement again.
  • The body undergoes visuomotor learning to adjust throwing style
  • A change in integration and visuomotor occurs to adapt.

Lab 3, Experiment 1: Metathoracic Leg Response

  • The metathoracic leg responds with differing amounts to flexion or extension.
  • No right or wrong answer, depends on pin placement and axon response.
  • Sensory neurons in the chordotonal organ synapse and respond to movement
  • Awareness of the movement around it is sensed by cockroaches.

Lab 3, Experiment 2: Chordotonal Organ and Leg Movement Angles

  • The chordotonal organ adjusts to different amounts (angles) of leg movements.
  • The firing frequency and time differences vary based on different angles.
  • The greater the angle, the more firing frequencies/action potentials.
  • As the angle movement increases, The chordotonal organs contain more stretch that increases the number of frequency potentials being sent along the afferent neuron. This enables cockroaches to be aware of the angle that their leg is bent.
  • As high firing frequency associated with increased leg movement cannot be maintained, The chordotonal organ undergoes sensory adaptation to filter out additional info that is no longer useful to the cockroach.
  • Phasic-tonic response shows high initial firing frequency that drops very quickly but doesn't hit zero; instead, it levels off.

Lab 4, Experiment 1: Electrical Activity vs. Grip Force

  • Electrical activity (nerve stimulation) adjusts to different amounts of grip force
  • As grip force increases, EMG activity increases.
  • At some point, EMG activity plateaus, indicating no more motor units can be recruited.
  • Tetanus is known as the act of muscles cannot fully relax in between stimulation.
  • As motor units increase, electrical activity increases, influencing the amount of grip force produced.

Lab 4, Experiment 2: EMG Activity and Reflex Stimulation

  • After reflex stimulation effects the EMG activity
  • The Body responses to stimuli quickly.
  • Stimuli does not require traveling to the brain for processing, thus creating a shorter response compared to reaction times.
  • Mechanosensory receptors, called muscle spindles, conduct this process.
  • Muscle spindles enter the spinal cord and synapse directly with motor neurons via a monosynaptic pathway
  • Stimulated neurons triggers nerve synapses with motor neurons, which travel to the same muscle group to cause a contraction, completing the reflex arc.
  • Muscle stretch causes muscle spindle excitation and results in muscle reflex contraction (stretch reflex).
  • Reflexes are important safety mechanisms that allow for faster responses.

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