18 Questions
What is the role of calcium in the Excitation-Contraction Coupling process?
Activates the ryanodine receptor to release stored calcium
What happens when myosin binds another ATP molecule?
It detaches from actin
What occurs during the latent period of a twitch contraction?
AP propagation along T-tubules
How does an action potential contribute to muscle contraction?
Increases cytosolic calcium levels
What is the significance of the Cross-Bridge Cycle in muscle contraction?
Facilitates the sliding of actin and myosin filaments
When does muscle relaxation occur?
When cytosolic calcium levels decrease
What is the main reason for using acetylcholinesterase inhibitors in treating certain conditions?
To inhibit the breakdown of acetylcholine, prolonging its action
Why are glucocorticoids sometimes used in treatments related to neural causes?
To decrease inflammation in neural tissues
In smooth muscle cells, what is responsible for anchoring thin filaments in place during contraction?
Dense bodies or dense plaques
What is the characteristic feature of smooth muscles that distinguishes them from skeletal muscles regarding their striped appearance?
Presence of sarcomeres
In smooth muscle contraction, which protein directly binds with calcium ions to initiate the process?
Calmodulin
What type of electrical activity allows some smooth muscle cells to generate action potentials without external signals?
Slow waves
What is the term for muscle contraction that produces tension and causes the muscle to change length?
Concentric contraction
What happens to the muscle length in eccentric contraction?
The muscle lengthens
What type of contraction occurs when the muscle changes tension but the length of the muscle stays the same?
Isometric contraction
What is the effect of increasing load on shortening velocity of a muscle?
Shortening velocity decreases
What does passive tension in a muscle refer to?
Tension due to titin protein
What happens to the tension in a muscle if a second action potential is produced before the muscle relaxes from the first?
Tension increases
Learn about the process of excitation-contraction coupling, where an action potential triggers muscle contraction, and the cross-bridge cycle that explains how myosin and actin interact to generate movement in muscles.
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