Examples of X-Linked Inheritance Diseases Quiz
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Questions and Answers

What is the probability that sons of an affected man and a carrier mother will be affected by an X-linked recessive disease?

  • 25%
  • 75%
  • 100%
  • 50% (correct)

Which of the following is NOT an X-linked recessive disease?

  • Marfan syndrome (correct)
  • Fragile X syndrome
  • Lesch Nyhan syndrome
  • Wiscott-Aldrich syndrome

If a daughter of an affected man inherits his mutated X chromosome, what is the potential outcome?

  • She will be affected.
  • She will have a 75% chance of being affected.
  • She will be a carrier. (correct)
  • She will be unaffected.

Which of the following diseases exhibits X-linked recessive inheritance?

<p>Duchenne muscular dystrophy (C)</p> Signup and view all the answers

What is the probability that sons of an affected man and an affected mother will be affected by an X-linked recessive disease?

<p>100% (D)</p> Signup and view all the answers

How do daughters of an affected man and carrier mother differ in their outcomes in X-linked recessive inheritance?

<p>Some are carriers and some are affected. (B)</p> Signup and view all the answers

Why can affected fathers not pass X-linked recessive traits to their sons?

<p>Because fathers give Y chromosomes to their sons (C)</p> Signup and view all the answers

Why are X-linked recessive traits more commonly expressed in males than in females?

<p>Males possess only one X chromosome (C)</p> Signup and view all the answers

What happens when a female is a carrier for an X-linked recessive disorder?

<p>She will not pass the disorder to her sons (B)</p> Signup and view all the answers

Why does male-to-male transmission of X-linked recessive traits not occur?

<p>Fathers give Y chromosomes to their sons (C)</p> Signup and view all the answers

How many mutated X chromosomes do females need to be affected by an X-linked recessive trait?

<p>Two (C)</p> Signup and view all the answers

Why are males who inherit an affected X chromosome from their mother more likely to exhibit X-linked recessive traits?

<p>Because they lack a second X chromosome to compensate for the mutation (D)</p> Signup and view all the answers

What is true about X-linked dominant inheritance?

<p>One copy of the allele is sufficient to cause the disorder (C)</p> Signup and view all the answers

Which of the following statements is correct regarding X-linked dominant inheritance?

<p>Mothers with the trait will always have affected daughters (D)</p> Signup and view all the answers

In X-linked dominant inheritance, if the father is affected by a disorder, which offspring will be affected?

<p>Only daughters (D)</p> Signup and view all the answers

What happens if a mother with an X-linked dominant disorder has a son?

<p>The son will always be affected (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of X-linked dominant inheritance?

<p>Affects more females than males (A)</p> Signup and view all the answers

In X-linked dominant inheritance, what is the inheritance pattern when both parents have the disorder?

<p>Sons have a chance to be affected depending on the type of X chromosome inherited (B)</p> Signup and view all the answers

Flashcards

What is the probability that sons of an affected man and a carrier mother will be affected by an X-linked recessive disease?

A male child will have a 50% chance of inheriting the mutated X chromosome from his mother and thus develop the disease. This is because he will receive either his mother's mutated X or his father's normal X.

Which of the following is NOT an X-linked recessive disease?

Marfan syndrome is an autosomal dominant disorder, meaning it's not linked to the X chromosome.

If a daughter of an affected man inherits his mutated X chromosome, what is the potential outcome?

A daughter of an affected man will always inherit the father's mutated X chromosome, but since she also receives a normal X from the mother, she becomes a carrier.

Which of the following diseases exhibits X-linked recessive inheritance?

Duchenne muscular dystrophy is a classic example of X-linked recessive inheritance, affecting primarily males.

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What is the probability that sons of an affected man and an affected mother will be affected by an X-linked recessive disease?

An affected male passes the mutated X chromosome. With a mother who also carries the mutated X, the son will inherit one mutated X from each parent, leading to a 100% probability of developing the disease.

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How do daughters of an affected man and carrier mother differ in their outcomes in X-linked recessive inheritance?

The daughters of an affected man and a carrier mother have varying outcomes: some inherit the mutated X chromosome and become carriers, while others inherit the normal X chromosome and remain unaffected.

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Why can affected fathers not pass X-linked recessive traits to their sons?

Males only inherit a Y chromosome from their father. X-linked recessive traits are carried on the X chromosome.

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Why are X-linked recessive traits more commonly expressed in males than in females?

Males have only one X chromosome, so if they inherit a mutated X chromosome for an X-linked recessive trait, there's no healthy X to compensate for the mutation, resulting in the disorder.

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What happens when a female is a carrier for an X-linked recessive disorder?

She will be a carrier and may pass the mutated X chromosome to her offspring but she won't exhibit the disease because she has another normal X chromosome.

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Why does male-to-male transmission of X-linked recessive traits not occur?

Fathers contribute a Y chromosome to their sons; X-linked recessive traits are passed down through the X chromosome.

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How many mutated X chromosomes do females need to be affected by an X-linked recessive trait?

Females have two X chromosomes. They need both X chromosomes to carry the mutated gene to exhibit an X-linked recessive trait.

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Why are males who inherit an affected X chromosome from their mother more likely to exhibit X-linked recessive traits?

Males have only one X chromosome. If they inherit the affected X chromosome from their mother, they will exhibit the trait because they don't have another X chromosome to compensate for it.

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What is true about X-linked dominant inheritance?

X-linked dominant inheritance means that if an individual inherits an X chromosome carrying the mutation, they'll display the disorder, regardless of the other X chromosome.

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Which of the following statements is correct regarding X-linked dominant inheritance?

In X-linked dominant inheritance, if the mother has the trait, she will always pass the mutated X to her daughters. This is because daughters inherit one X from each parent.

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In X-linked dominant inheritance, if the father is affected by a disorder, which offspring will be affected?

An affected father will always pass on the mutated X chromosome to his daughters. Because he is giving his Y chromosome to his sons, they will not inherit the disorder.

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What happens if a mother with an X-linked dominant disorder has a son?

Since the mother has the mutated X chromosome, she will pass it on to her son. Thus, the son will always be affected by the X-linked dominant disorder.

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Which of the following is NOT a characteristic of X-linked dominant inheritance?

X-linked dominant inheritance is more commonly observed in females. Due to the dominant nature of the trait, even one mutated X chromosome is sufficient for the disorder to be expressed.

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In X-linked dominant inheritance, what is the inheritance pattern when both parents have the disorder?

Since both parents have the disorder, the sons will be affected if they receive the mutated X chromosome from their mother.

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