Examen Final PATO - Síndromes y Coagulación

Study Notes

Examen Final PATO - Notes

Síndrome de Ehlers-Danlos (SED): Characterized by autosomal dominant transmission in most cases.
Autosomal Recessive Transmission: Anemia of sickle cells (drepanocytic anemia) displays this pattern.
Necrosis Fibrinoide of Blood Vessel Walls: Associated with immunoglobulins and complement deposition.
Disseminated Intravascular Coagulation (DIC): Involves systemic thrombin activation.
Atherosclerotic Plaque Localization: Most frequently found in the abdominal aorta.
Necrosis Fibrinoide: A significant manifestation of Type III hypersensitivity.
Granuloma in Granulation Tissue: Characterized by a band of fibrinoid necrosis around a granuloma.
DiGeorge Syndrome: A thymus development disorder.
Saddle Emboli: Often preceded by deep vein thrombosis.
Thyroid Autoimmunity: Characterized by lymphocytes in all stages of maturation, including Hurthle cells.
Antigen-Presenting Cells: Lymphocytes B are prominent in germinal centers of lymph nodes and spleen.
Tissue Factor: Synthesized by vascular endothelium in hemostasis.
Anergy: A prolonged, irreversible functional inactivation of dendritic cells.
Mast Cell Mediators: Include phospholipase A-2, platelet-activating factor (PAF), prostaglandins, and histamine.
Marfan Syndrome Characteristics: Not caused by a collagen coding alteration.
Hyperacute Rejection: Mediated by pre-existing antibodies against donor antigens.
Duchenne Muscular Dystrophy: A sex-linked recessive disorder.
Amyloid Detection: Congo red staining for birefringence under polarized light is definitive.
Generalized Edema Causes, Except: Lymphatic obstruction.
Psoriasis Mechanism: Type IV hypersensitivity..
Turner Syndrome (45,X): Diagnosed through karyotyping.
Large Subcutaneous Hematoma: Called an ecchymosis.
Blood Vessel Wall Necrosis: A characteristic of type III hypersensitivity.
Autoantibody Targets in Pernicious Anemia: Parietal cells of the stomach.
Type III Hypersensitivity: Characterized by immune complex deposition.
Type I Hypersensitivity: Characterized by an immediate response.
Antinuclear Antibodies (ANAs): Not specific to anti-phospholipids.
Goodpasture's Syndrome Pathogenesis: Not a type III hypersensitivity manifestation.
Peri-Orbital Edema: Suggests renal involvement.
Amyloidosis: Characteristic of plasma cell neoplasms in multiple myeloma.
Vascular Congestion with Hemosiderin-laden Macrophages: A sign of vascular congestion.
Primary Lymphoid Organs: Bone marrow and thymus.
Thrombosis Predisposition: Stasis is a major factor.