Liver Failure

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35 Questions

Which of the following is a symptom of Cushing's syndrome?

Stupor and coma

Which syndrome is associated with small-cell lung cancer?

Lambert-Eaton myasthenic syndrome

What is the most common symptom of venous thromboembolism (VTE)?

Breathlessness

What is the recommended treatment for VTE?

Low molecular weight (LMW) heparin

Which of the following is a paraneoplastic syndrome associated with lung cancer?

Dermatomyositis

What percentage of people with cancer are thought to be affected by paraneoplastic syndromes?

Less than 1%

Which of the following skin disorders may require treatment by a specialist dermatologist to manage symptoms?

Dermatomyositis

What is the recommended treatment for paraneoplastic pemphigus?

Ciclosporin

Which of the following is a contributing factor to weakness in individuals approaching death?

Cachexia

What is the definition of cachexia?

A state of involuntary weight loss

Which of the following is NOT a potential cause of weakness in individuals approaching death?

Age-related loss of muscle mass

Which of the following drug therapies may be effective in managing weakness in individuals approaching death?

Steroids

Which of the following is a symptom of hypercalcaemia of malignant disease?

Increased urinary output

Which of the following is a cause of anaemia in patients with advanced or chronic disease?

Chronic renal failure

Which of the following is a treatment option for cachexia?

Favourite foods

Which of the following is a poor prognostic sign in patients with dementia?

Declining oral intake leading to significant weight loss

Which of the following is NOT a recommended strategy for improving nutrition in palliative care?

Maintaining comfort and providing weight gain throughout the terminal phase

What is the recommended initial hydration method for a patient with renal failure?

Intravenous rehydration with normal saline

Which drug is NOT recommended for pain management in patients with renal failure?

Morphine

How can creatinine clearance be calculated using the Cockcroft and Gault equation?

CrCl (mLs/min) = (140-age) x ideal body weight (kg) / (plasma creatinine (umol/L) x 0.8)

Which of the following is NOT a common deprescribing anti-hypertensive medication mentioned in the text?

ACE inhibitors

What is the recommended approach for deprescribing medications?

Deprescribe one or two medications at a time

Which medication is NOT recommended to be deprescribed in patients with heart failure?

Beta-blockers

What is the recommended approach for managing haemorrhage in palliative care?

Treat with urgency and consider appropriate interventions

Which medication is NOT recommended for oral bleeding in palliative care?

Midazolam

What is the recommended approach for upper gastrointestinal bleeding in palliative care?

Discontinue NSAIDs

Which of the following is a measure of how well the liver can clear drugs?

INR levels

What is deprescribing in palliative care?

The process of ceasing inappropriate medications safely and effectively

What is one of the enablers for deprescribing?

Inconvenience of medication taking

What should be considered when deprescribing a medication?

Pharmacodynamics and pharmacokinetics of other medications

Which medication is NOT recommended to be deprescribed in patients with heart failure?

Beta-blockers

What is the recommended approach for deprescribing medications?

Deprescribe one or two medications at a time

Which of the following is a symptom of hypercalcaemia of malignant disease?

Bone pain

What is the recommended approach for managing haemorrhage in palliative care?

Use red towels

Which of the following is a paraneoplastic syndrome associated with lung cancer?

Paraneoplastic pemphigus

Test your knowledge on the symptoms and management of liver failure, including liver metastases, liver primary, and alcohol abuse/hepatitis. Explore the relationship between liver function and the dosage of drugs that are renally cleared.

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