Evolution of Epigenetics: A Brief History
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Questions and Answers

What sits at the base of the nucleosome near DNA, binding to the linker region of the DNA?

  • Histone H3
  • Histone H1 (correct)
  • Histone H4
  • Histone H2A

What is the space between adjacent nucleosomes approximately?

  • 30 nm
  • 14 nm (correct)
  • 8 nm
  • 2 nm

What was the result when isolated chromatin was treated with nuclease and analyzed by agarose gel electrophoresis?

  • A DNA ladder of fragments that differed in length by 100 bp
  • A single long DNA strand
  • A DNA ladder of fragments that differed in length by 200 bp (correct)
  • No visible changes

Which type of DNA is generally not active due to its compact nature?

<p>Heterochromatin DNA (A)</p> Signup and view all the answers

What plays an important role in regulating all DNA processes, including transcription, repair, and replication?

<p>Chromatin modifications (A)</p> Signup and view all the answers

What proteins 'read' the chromatin modifications and bind to them at specific regions, thus facilitating gene transcription?

<p>Epigenetic regulators (D)</p> Signup and view all the answers

What is the fundamental repeating unit of chromatin?

<p>Histones (A)</p> Signup and view all the answers

What surrounds the nucleus in eukaryotic cells?

<p>Nuclear membrane (B)</p> Signup and view all the answers

What provides a scaffold for the packaging of the entire genome?

<p>Chromatin (B)</p> Signup and view all the answers

What concept was used to describe how cell fates are established during development?

<p>Epigenetics (D)</p> Signup and view all the answers

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