10 Questions
What sits at the base of the nucleosome near DNA, binding to the linker region of the DNA?
Histone H1
What is the space between adjacent nucleosomes approximately?
14 nm
What was the result when isolated chromatin was treated with nuclease and analyzed by agarose gel electrophoresis?
A DNA ladder of fragments that differed in length by 200 bp
Which type of DNA is generally not active due to its compact nature?
Heterochromatin DNA
What plays an important role in regulating all DNA processes, including transcription, repair, and replication?
Chromatin modifications
What proteins 'read' the chromatin modifications and bind to them at specific regions, thus facilitating gene transcription?
Epigenetic regulators
What is the fundamental repeating unit of chromatin?
Histones
What surrounds the nucleus in eukaryotic cells?
Nuclear membrane
What provides a scaffold for the packaging of the entire genome?
Chromatin
What concept was used to describe how cell fates are established during development?
Epigenetics
Explore the evolution of the term 'epigenetics' over the last 50 years and its significance in understanding cell fates during development. Delve into the differences between geneticists and epigeneticists, the role of ncRNAs, and the modulation of genetic material.
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