Evolution of Epigenetics: A Brief History
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Questions and Answers

What sits at the base of the nucleosome near DNA, binding to the linker region of the DNA?

  • Histone H3
  • Histone H1 (correct)
  • Histone H4
  • Histone H2A
  • What is the space between adjacent nucleosomes approximately?

  • 30 nm
  • 14 nm (correct)
  • 8 nm
  • 2 nm
  • What was the result when isolated chromatin was treated with nuclease and analyzed by agarose gel electrophoresis?

  • A DNA ladder of fragments that differed in length by 100 bp
  • A single long DNA strand
  • A DNA ladder of fragments that differed in length by 200 bp (correct)
  • No visible changes
  • Which type of DNA is generally not active due to its compact nature?

    <p>Heterochromatin DNA</p> Signup and view all the answers

    What plays an important role in regulating all DNA processes, including transcription, repair, and replication?

    <p>Chromatin modifications</p> Signup and view all the answers

    What proteins 'read' the chromatin modifications and bind to them at specific regions, thus facilitating gene transcription?

    <p>Epigenetic regulators</p> Signup and view all the answers

    What is the fundamental repeating unit of chromatin?

    <p>Histones</p> Signup and view all the answers

    What surrounds the nucleus in eukaryotic cells?

    <p>Nuclear membrane</p> Signup and view all the answers

    What provides a scaffold for the packaging of the entire genome?

    <p>Chromatin</p> Signup and view all the answers

    What concept was used to describe how cell fates are established during development?

    <p>Epigenetics</p> Signup and view all the answers

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