Evolution Lecture 10: Quantitative Traits and Genetics - Darwin Day Celebration
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Questions and Answers

What is the term used to describe the interaction between alleles at different loci?

  • Epistasis (correct)
  • Recombination
  • Linkage equilibrium
  • Quantitative genetics

Which type of trait tends to vary continuously among individuals?

  • Mendelian traits
  • Monogenic traits
  • Binary traits
  • Polygenic traits (correct)

What generates genetic variation by mixing alleles?

  • Quantitative genetics
  • Polygenic traits
  • Recombination (correct)
  • Linkage equilibrium

In quantitative genetics, what is the term for the mixing and matching of alleles?

<p>Linkage equilibrium (B)</p> Signup and view all the answers

Which type of traits have a complex genetic basis influenced by many genetic loci?

<p>Polygenic traits (C)</p> Signup and view all the answers

What occurs if the occurrence of an allele at one locus is nonrandomly associated with another locus?

<p>Linkage disequilibrium (D)</p> Signup and view all the answers

What does linkage disequilibrium in cats reflect?

<p>Breed history (A)</p> Signup and view all the answers

Which method links traits with genes through the study of genomic regions?

<p>Quantitative trait locus (QTL) analysis (A)</p> Signup and view all the answers

What is primarily identified by Genome-wide association studies (GWAS)?

<p>Variants and genomic regions associated with particular traits (D)</p> Signup and view all the answers

What is often used in QTL analysis to identify genomic regions responsible for coat color in mice?

<p>Single-nucleotide polymorphisms (SNPs) (D)</p> Signup and view all the answers

What is used to understand the link between phenotype and genotype?

<p>Recombination (D)</p> Signup and view all the answers

What does the degree of linkage of different loci depend on?

<p>Distance between them (B)</p> Signup and view all the answers

What does QTL analysis aim to link?

<p>Traits with genes (B)</p> Signup and view all the answers

'Presence or absence of an allele at a second locus' is associated with which genetic concept?

<p>Linkage disequilibrium (D)</p> Signup and view all the answers

What type of substitution in DNA sequences does not change the encoded protein?

<p>Synonymous substitutions (D)</p> Signup and view all the answers

What indicates positive selection on DNA sequences when compared to synonymous sites?

<p>Faster evolution (A)</p> Signup and view all the answers

What does a slower evolution than synonymous sites indicate on DNA sequences?

<p>Purifying selection (B)</p> Signup and view all the answers

What is the dN/dS ratio also known as?

<p>Ka/Ks ratio (B)</p> Signup and view all the answers

Which ratio would be expected for a gene under positive selection?

<p>dN/dS &gt; 1 (A)</p> Signup and view all the answers

What could lead to a dN/dS ratio of less than 1?

<p>Purifying selection (D)</p> Signup and view all the answers

In the context of evolution rates, what could explain more similar dN/dS ratios between BRCA1 genes and immune genes?

<p>&quot;Host-virus arms race&quot; (D)</p> Signup and view all the answers

What mechanism spreads adaptive alleles through a population more quickly than recombination acts to separate them from neighboring alleles?

<p>&quot;Selective sweep&quot; (B)</p> Signup and view all the answers

What leaves a signature in neighboring alleles due to its rapid spread through a population?

<p><strong>Selective sweep</strong> (A)</p> Signup and view all the answers

What do gene trees depict?

<p>Phylogeny of DNA sequence at a particular locus (D)</p> Signup and view all the answers

Which term is used to describe the common ancestry represented by nodes in gene trees?

<p>Coalescence (D)</p> Signup and view all the answers

What can tracking phylogenies back in time lead to?

<p>Population bottlenecks (D)</p> Signup and view all the answers

What may cause shallow coalescence in gene trees?

<p>Positive selection (A)</p> Signup and view all the answers

Why may gene trees and species trees not always match?

<p>Incomplete lineage sorting (C)</p> Signup and view all the answers

In gene trees vs. species trees, what does a gene tree depict specifically?

<p>Evolutionary history of DNA sequences at a locus (C)</p> Signup and view all the answers

What does the dN/dS ratio measure in molecular evolution studies?

<p>Rate of nonsynonymous mutations (B)</p> Signup and view all the answers

'Neutral theory' in molecular evolution suggests that most mutations are:

<p>'Not subject to natural selection' (B)</p> Signup and view all the answers

'Selection' on DNA sequences usually affects which type of mutations?

<p>'Nonsynonymous' (C)</p> Signup and view all the answers

'Rate of molecular evolution' refers to the speed at which:

<p>'Mutations occur' (A)</p> Signup and view all the answers

What type of trait does the G âž” T mutation represent in terms of nucleotides (bases)?

<p>Synapomorphy (C)</p> Signup and view all the answers

What term describes the evolutionary relationships among different taxa?

<p>Phylogeny (D)</p> Signup and view all the answers

What kind of genealogies do genetic loci have for their nucleotides (bases)?

<p>Alleles (A)</p> Signup and view all the answers

In genetic terms, what are the Gs in Ts?

<p>Alleles (A)</p> Signup and view all the answers

What is the term used to describe the mixing and matching of alleles?

<p>Genetic recombination (C)</p> Signup and view all the answers

What does a synapomorphy indicate in terms of evolutionary relationships?

<p>Common ancestor (B)</p> Signup and view all the answers

What happens when alleles at different loci are nonrandomly associated?

<p>Linkage disequilibrium (C)</p> Signup and view all the answers

What type of genetic variation results from introgression?

<p>Synapomorphy (A)</p> Signup and view all the answers

Which term describes the mixing of genetic material between different species or populations?

<p>Gene flow (A)</p> Signup and view all the answers

What is the neutral theory of molecular evolution proposed by Motoo Kimura in 1968?

<p>Most evolution at the molecular level is neutral and driven by genetic drift. (A)</p> Signup and view all the answers

What does synonymous (silent) mutation refer to in terms of DNA sequences?

<p>It does not affect the amino acid sequence of the protein. (B)</p> Signup and view all the answers

What is the primary difference between synonymous and nonsynonymous mutations?

<p>Nonsynonymous mutations are generally selectively neutral. (C)</p> Signup and view all the answers

What aspect of DNA evolution does the rate of molecular evolution refer to?

<p>The variability in mutation rates among different DNA segments. (D)</p> Signup and view all the answers

In terms of DNA evolution, what is meant by '4-fold degenerate sites'?

<p>DNA regions where mutations do not lead to amino acid changes due to redundancy in the genetic code. (C)</p> Signup and view all the answers

How does natural selection influence the fixation of mutations according to the neutral theory of molecular evolution?

<p>Natural selection has no role in fixing mutations based on fitness advantages. (C)</p> Signup and view all the answers

What does the dN/dS ratio indicate when analyzing DNA sequences?

<p>'dN/dS' is used to estimate the selective pressures acting on protein-coding genes. (A)</p> Signup and view all the answers

How do different types of DNA segments evolve according to the information provided?

<p>'m', 'n', and 'c' segments evolve at different rates but consistently within organisms. (A)</p> Signup and view all the answers

'Neutral theory of molecular evolution postulates that ___.'

<p>'most changes at the molecular level are due to genetic drift.' (A)</p> Signup and view all the answers

What term describes a homologous gene that arises due to gene duplication?

<p>Paralog (C)</p> Signup and view all the answers

Which process involves the co-option of a particular gene for a totally different function as a result of a mutation?

<p>Gene recruitment (D)</p> Signup and view all the answers

What led to the evolution of the ability to consume citrate in E. coli?

<p>Gene duplication (C)</p> Signup and view all the answers

Which statement best describes paralogs?

<p>Genes that arise from gene duplication (D)</p> Signup and view all the answers

What is the term for the process of reorganizing a preexisting regulatory network resulting in a major evolutionary event?

<p>Gene recruitment (D)</p> Signup and view all the answers

Which event is an example of the evolution of a complex trait through gene duplication?

<p>Consumption of citrate in E. coli (C)</p> Signup and view all the answers

What is the term for the recruitment of venom genes from genes expressed in multiple snake organs?

<p>Gene recruitment (D)</p> Signup and view all the answers

What is the term used to describe similarity in traits or sequences due to inheritance from a common ancestor?

<p>Homology (D)</p> Signup and view all the answers

Which genetic concept reflects the idea that flies and mice use homologous genes for dorsal-ventral patterning?

<p>Homology (D)</p> Signup and view all the answers

What does the expression of HOXd13 in zebrafish and mouse embryos demonstrate about gene evolution?

<p>Shared ancestry (B)</p> Signup and view all the answers

Why are flies and mice more likely to have homologous genes for dorsal-ventral patterning?

<p>Shared ancient genetic toolkit (D)</p> Signup and view all the answers

What aspect of genetic networks often controls complex adaptations?

<p>Regulatory networks (C)</p> Signup and view all the answers

Which of the following can have drastic effects on animal embryo development?

<p>Mutations to genes at the top of the hierarchy (A)</p> Signup and view all the answers

What controls the shared ancestry of complex traits according to the text?

<p>Genes, proteins, RNA, control regions, repressors, and transcription factors (C)</p> Signup and view all the answers

Which genetic concept experiences selection for a common, often novel, function?

<p>Coexpressed traits (B)</p> Signup and view all the answers

What are complex adaptations controlled by?

<p>Genes, proteins, RNA, control regions, repressors, and other transcription factors (D)</p> Signup and view all the answers

What is often involved in the development of animal embryos according to the text?

<p>Hierarchical gene organization (C)</p> Signup and view all the answers

What is the focus of the lecture 'Quantitative Traits and Genetics'?

<p>Genetic linkage (D)</p> Signup and view all the answers

Which concept refers to the occurrence of an allele at one locus being nonrandomly associated with the presence of an allele at another locus?

<p>Linkage disequilibrium (C)</p> Signup and view all the answers

What does 'Polygenic trait' refer to in genetics?

<p>Trait influenced by many genetic loci (B)</p> Signup and view all the answers

Which term describes the evolutionary relationships among different taxa?

<p>Phylogenies (C)</p> Signup and view all the answers

What generates genetic variation by mixing alleles?

<p>Recombination (D)</p> Signup and view all the answers

What type of traits tend to vary continuously among individuals?

<p>Polygenic traits (A)</p> Signup and view all the answers

In quantitative genetics, what is the term for the mixing and matching of alleles?

<p>Genetic linkage (C)</p> Signup and view all the answers

What does linkage disequilibrium in cats reflect, according to Alhaddad et al. 2013?

<p>Individual genetic variations within a breed (C)</p> Signup and view all the answers

What does Quantitative Trait Locus (QTL) analysis aim to link?

<p>Genomic regions responsible for specific traits (B)</p> Signup and view all the answers

What do Genome-wide association studies (GWAS) identify?

<p>Variants and genomic regions associated with particular traits (C)</p> Signup and view all the answers

How is the relationship between phenotype and genotype understood in QTL analysis?

<p>By linking genomic regions with specific loci (A)</p> Signup and view all the answers

What is the main focus of GWAS according to Palmer and Kronforst. 2020?

<p>Identifying genes involved in mimicry in swallowtail butterflies (A)</p> Signup and view all the answers

How is linkage disequilibrium influenced in close loci on the same chromosome?

<p>By the distance between loci (B)</p> Signup and view all the answers

Why are single-nucleotide polymorphisms (SNPs) often used in QTL analysis?

<p>To identify genomic regions responsible for specific traits (B)</p> Signup and view all the answers

What can be inferred about loci close together on the same chromosome based on the degree of linkage?

<p>They demonstrate a nonrandom association. (A)</p> Signup and view all the answers

What is a main requirement for natural selection to occur?

<p>High heritability (A)</p> Signup and view all the answers

Which component of fitness refers to an individual's reproductive success?

<p>Fecundity (B)</p> Signup and view all the answers

Which scientist contributed significantly to the understanding of natural selection but is not always credited with the discovery?

<p>Alfred Russel Wallace (B)</p> Signup and view all the answers

What type of selection favors alleles that lower fitness?

<p>Negative selection (A)</p> Signup and view all the answers

Which concept describes the contribution of individuals with one genotype compared to the fittest genotype in the population?

<p>Relative fitness (B)</p> Signup and view all the answers

What do organisms need to possess for natural selection to occur?

<p>High heritability (B)</p> Signup and view all the answers

Which scenario would violate Hardy-Weinberg equilibrium?

<p>Natural selection (A)</p> Signup and view all the answers

'Fitness' in evolutionary terms is best described as:

<p>'Survival and reproduction' (B)</p> Signup and view all the answers

What type of selective response is favored when intermediate size is selected for?

<p>Stabilizing selection (D)</p> Signup and view all the answers

'Variation' in the context of natural selection refers to differences in:

<p>'Genetic makeup' (C)</p> Signup and view all the answers

In the context of the text, what property reflects the genotype of an individual?

<p>Gall diameter (D)</p> Signup and view all the answers

What type of selection leads to the evolution of similar ecomorphs like the multicolored tanager?

<p>Directional selection (C)</p> Signup and view all the answers

What concept is used to describe the heritability of gall diameter in the text?

<p>Genetic correlation (A)</p> Signup and view all the answers

What type of genetic change is favored when low-Eda alleles are present at low frequencies in marine environments?

<p>Hardy-Weinberg equilibrium violation (B)</p> Signup and view all the answers

What does the rapid loss of armor in Loberg Lake indicate about evolution?

<p>'Repeated evolution' of low-plate phenotype (C)</p> Signup and view all the answers

Which genetic concept involves the production of variable lateral plates in stickleback due to Eda signaling?

<p>'Quantitative trait locus (QTL) analysis' (C)</p> Signup and view all the answers

What aspect of natural selection does the repeated evolution of Anole 'ecomorphs' illustrate?

<p>'Directional selection' (B)</p> Signup and view all the answers

'Replicated changes as natural experiments' suggest which evolutionary outcome?

<p>'Parallel evolution' (C)</p> Signup and view all the answers

'High-Eda' and 'Low-Eda' alleles affecting armor in sticklebacks are examples of what genetic phenomenon?

<p>'Hardy-Weinberg equilibrium violation' (C)</p> Signup and view all the answers

How did severe drought affecting the availability of food lead to the evolution of larger-beaked birds?

<p>Harder, woody seeds became the only available food, favoring larger-beaked birds. (B)</p> Signup and view all the answers

In the context of natural selection, what does 'directional selection' refer to?

<p>Selection that favors individuals at one extreme of the phenotypic range. (A)</p> Signup and view all the answers

What factor can lead to rapid changes in a population according to the text?

<p>Natural selection. (A)</p> Signup and view all the answers

How does coat color variation affect fitness in oldfield mice according to Hopi Hoekstra's research?

<p>It affects the ability of mice to blend into their environment and avoid predators. (B)</p> Signup and view all the answers

What is implied by 'heritability' in the context of coat color variation affecting fitness in oldfield mice?

<p>The ability of coat color to be passed down from one generation to the next. (D)</p> Signup and view all the answers

What phenomenon can lead to differences in fitness and survival among individuals in a population?

<p>Natural selection. (A)</p> Signup and view all the answers

'Crypsis' in feather lice refers to:

<p>'Cryptic coloration' that helps lice blend into their host's feathers. (C)</p> Signup and view all the answers

'Impaired preening ability' in painted lice studied by Bush et al. 2019 implies:

<p>'Preening ability' is essential for lice survival and reproduction. (A)</p> Signup and view all the answers

'Experimentally induced evolution toward lighter coloration in pigeon lice' illustrates:

<p>'Artificial' selection pressures leading to changes in lice coloration. (A)</p> Signup and view all the answers

What do experiments by Bush et al. 2019 on more conspicuous lice being removed by pigeons suggest?

<p>Pigeons selectively remove more conspicuous lice, indicating a predator-prey interaction. (C)</p> Signup and view all the answers

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