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Questions and Answers
Which of the following is a mechanism of fetal tolerance in pregnant mammals?
Which of the following is a mechanism of fetal tolerance in pregnant mammals?
- Exclusion of inflammatory cells from the pregnant uterus (correct)
- Generation of harmful Th1 responses in the healthy pregnant uterus
- Decreased generation of peripheral regulatory T cells
- Increased antigen presentation in the placenta
What is the consequence of the failure of self-tolerance?
What is the consequence of the failure of self-tolerance?
- Development of autoimmunity (correct)
- Generation of peripheral FoxP3+ regulatory T cells
- Increased antigen presentation in the placenta
- Exclusion of inflammatory cells from the pregnant uterus
What is the correlation between placentation and the ability to generate stable peripheral regulatory T cells?
What is the correlation between placentation and the ability to generate stable peripheral regulatory T cells?
- No correlation
- Weak correlation
- Negative correlation
- Strong correlation (correct)
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