Eukaryotic Gene Expression Regulation Quiz

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What determines the cellular concentration of a protein in eukaryotes?

Synthesis of the primary RNA transcript (transcription) (correct)

Posttranslational modification of proteins

Protein targeting and transport

mRNA degradation

Which process is important for normal development and differentiation in eukaryotes?

Posttranscriptional modification of mRNA

Protein synthesis (translation)

Chromatin remodeling (correct)

Protein degradation

What is the role of epigenetic modifications in eukaryotes?

They alter chromatin structure (correct)

They alter DNA accessibility

They enhance posttranscriptional modification of mRNA

They increase protein degradation

Which factor provides a barrier against the ready association of transcription factors with specific DNA regions in eukaryotes?

Presence of nucleosomes complexes of histones and DNA Signup and view all the answers

What can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

Epigenetic modifications Signup and view all the answers

Which modification reduces the positive charge of histone tails and decreases the binding affinity of histones for DNA?

Histone acetylation Signup and view all the answers

What is the specific effect of histone deacetylation?

Increases the binding affinity of histones for DNA Signup and view all the answers

Which type of regulatory sequence influences gene expression only on the same chromosome?

Cis-acting regulatory elements Signup and view all the answers

What is the role of trans-acting molecules in gene regulation?

They facilitate transcription initiation complex formation Signup and view all the answers

What is the evidence that methylation of deoxycytidine residues in DNA may cause changes in chromatin?

Methylation in DNA can inhibit active transcription Signup and view all the answers

Which of the following is true about histone acetylation and deacetylation?

Histone acetylation occurs on lysine residues in the amino terminal tails of histone molecules. Signup and view all the answers

What is the specific effect of histone methylation?

It inhibits the active transcription of genes in mouse liver. Signup and view all the answers

Which regulatory sequences influence gene expression only on the same chromosome?

Cis-acting regulatory elements Signup and view all the answers

What is the role of trans-acting molecules in gene regulation?

They diffuse through the cell from their site of synthesis to their DNA-binding site. Signup and view all the answers

What can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

Acute demethylation of deoxycytidine residues in a specific region of a gene Signup and view all the answers

Which process is responsible for altering chromatin structure in eukaryotes?

DNA methylation Signup and view all the answers

What is the role of nucleosomes in gene regulation in eukaryotes?

They provide a barrier against the association of transcription factors with specific DNA regions Signup and view all the answers

What contributes to the differential expression of a gene in different tissues in eukaryotes?

Chromatin remodeling Signup and view all the answers

Which process is important for normal development and differentiation in eukaryotes?

Epigenetic modifications (DNA methylation and histone modification) Signup and view all the answers

What can be modified by exogenous influences and can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

Epigenetic modifications (DNA methylation and histone modification) Signup and view all the answers

Eukaryotic Gene Expression Regulation Quiz

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Questions and Answers

What determines the cellular concentration of a protein in eukaryotes?

Which process is important for normal development and differentiation in eukaryotes?

What is the role of epigenetic modifications in eukaryotes?

Which factor provides a barrier against the ready association of transcription factors with specific DNA regions in eukaryotes?

What can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

Which modification reduces the positive charge of histone tails and decreases the binding affinity of histones for DNA?

What is the specific effect of histone deacetylation?

Which type of regulatory sequence influences gene expression only on the same chromosome?

What is the role of trans-acting molecules in gene regulation?

What is the evidence that methylation of deoxycytidine residues in DNA may cause changes in chromatin?

Which of the following is true about histone acetylation and deacetylation?

What is the specific effect of histone methylation?

Which regulatory sequences influence gene expression only on the same chromosome?

What is the role of trans-acting molecules in gene regulation?

What can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

Which process is responsible for altering chromatin structure in eukaryotes?

What is the role of nucleosomes in gene regulation in eukaryotes?

What contributes to the differential expression of a gene in different tissues in eukaryotes?

Which process is important for normal development and differentiation in eukaryotes?

What can be modified by exogenous influences and can contribute to or be the result of environmental alterations of phenotype in eukaryotes?

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