Podcast
Questions and Answers
Which term refers to the proteins that help regulate the cell cycle by activating cyclin-dependent kinases (CDKs)?
Which term refers to the proteins that help regulate the cell cycle by activating cyclin-dependent kinases (CDKs)?
- CDKs
- Mitogens
- Cyclins (correct)
- CKIs
What is the role of E2F in the eukaryotic cell cycle?
What is the role of E2F in the eukaryotic cell cycle?
- To inhibit CDK activity
- To induce apoptosis
- To enhance cyclin degradation
- To promote the transition past the restriction point (correct)
What occurs if error-free DNA synthesis is not completed between the S and G2 phases?
What occurs if error-free DNA synthesis is not completed between the S and G2 phases?
- Surveillance mechanisms arrest cell growth (correct)
- The cell progresses to mitosis
- The cell undergoes replication
- Cyclin production increases
Which protein complex is involved in the regulation of the transition from metaphase to anaphase?
Which protein complex is involved in the regulation of the transition from metaphase to anaphase?
Which phase of the cell cycle directly follows the G1 phase?
Which phase of the cell cycle directly follows the G1 phase?
What do CKIs refer to in the context of the eukaryotic cell cycle?
What do CKIs refer to in the context of the eukaryotic cell cycle?
What is a potential outcome if surveillance mechanisms detect cell cycle errors?
What is a potential outcome if surveillance mechanisms detect cell cycle errors?
Which of the following best describes the Start/Restriction point in the cell cycle?
Which of the following best describes the Start/Restriction point in the cell cycle?
Flashcards
CDK
CDK
Cyclin-dependent kinase; a protein kinase that is active only when bound to a cyclin.
Cyclin
Cyclin
A protein whose concentration fluctuates cyclically in the cell cycle, activating CDKs.
Start/Restriction point
Start/Restriction point
A critical point in G1 where the cell commits to entering the cell cycle. It's a crucial checkpoint in the cell cycle.
APC/C
APC/C
Signup and view all the flashcards
SCF
SCF
Signup and view all the flashcards
CKI
CKI
Signup and view all the flashcards
Mitogens
Mitogens
Signup and view all the flashcards
E2F
E2F
Signup and view all the flashcards
Study Notes
Eukaryotic Cell Cycle
- The eukaryotic cell cycle (G1, S, G2, M) seems simple, but is highly regulated
- Specific proteins, cellular readiness, and completion of previous stages are needed to initiate a new phase.
- DNA synthesis must be error-free during the S to G2 transition
- Cells with incomplete or damaged DNA are prevented from progressing via surveillance mechanisms.
- Apoptosis or mutations can lead to cancer development.
Cell Cycle Phases
- The cell cycle includes phases G1, S, G2, and M.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
