CNS

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Questions and Answers

Which of the following is a primary function of astrocytes?

  • Transmitting electrical signals rapidly across long distances.
  • Cleaning up cellular debris and pathogens in the CNS.
  • Forming the myelin sheath around axons in the PNS.
  • Maintaining a stable chemical environment for neurons. (correct)

Multipolar neurons are characterized by having one dendrite and one axon.

False (B)

What is the primary role of interneurons within the central nervous system?

linking sensory and motor neurons

In the context of impulse transmission, increased release of a mediator at a synapse leads to ______.

<p>facilitation</p> Signup and view all the answers

Match the following glial cells with their primary function within the CNS.

<p>Astrocytes = Regulation of the chemical environment of neurons Oligodendrocytes = Myelination of axons Microglia = Immune defense and debris cleanup Ependymal cells = Lining ventricles and aiding CSF circulation</p> Signup and view all the answers

Which type of glial cell myelinates axons in the peripheral nervous system (PNS)?

<p>Schwann cells (C)</p> Signup and view all the answers

The afferent division of the PNS is responsible for transmitting motor commands from the CNS to muscles and glands.

<p>False (B)</p> Signup and view all the answers

What is the key function of the ganglia located within the peripheral nervous system?

<p>relay stations and contain cell bodies of neurons</p> Signup and view all the answers

The white matter of the spinal cord is characterized by the presence of ______ axons.

<p>myelinated</p> Signup and view all the answers

Match each cranial nerve with its primary function:

<p>Olfactory nerve = Smell Optic nerve = Vision Vagus nerve = Controls heart rate and digestion Hypoglossal nerve = Tongue movement</p> Signup and view all the answers

Which feature distinguishes the autonomic nervous system (ANS) from the somatic nervous system (SNS)?

<p>ANS involves a two-neuron chain from CNS to effector; SNS involves a single neuron (C)</p> Signup and view all the answers

The brainstem consists of the cerebrum, diencephalon and cerebellum.

<p>False (B)</p> Signup and view all the answers

What is the general role of the thalamus in sensory processing?

<p>relay and process sensory information</p> Signup and view all the answers

The ventral anterior and ventrolateral nuclei of the thalamus are associated with ______ functions.

<p>motor</p> Signup and view all the answers

Match the thalamic sensory relay nuclei with their corresponding sensory system.

<p>Lateral geniculate nucleus = Visual system Medial geniculate nucleus = Auditory system Ventral basal complex = Somatosensory system</p> Signup and view all the answers

Which of the following is a region within the diencephalon responsible for regulating thirst, hunger, and thermoregulation?

<p>Hypothalamus (B)</p> Signup and view all the answers

The cerebral cortex is primarily composed of white matter.

<p>False (B)</p> Signup and view all the answers

What is the general function of the reticular formation in regulating states of consciousness?

<p>filtering incoming stimuli and regulating sleep-wake cycles</p> Signup and view all the answers

The alpha rhythm in an EEG is associated with a state of relaxed wakefulness and is typically replaced by faster, lower-voltage activity during EEG ______.

<p>arousal</p> Signup and view all the answers

Match each EEG rhythm with its associated mental state:

<p>Alpha = Relaxed wakefulness with closed eyes Beta = Alertness, active thinking, REM sleep Theta = Deep nREM sleep, children's brain Delta = Deep nREM sleep, infantile brain</p> Signup and view all the answers

Which brain structure is highly involved in the regulation of the sleep-wake transition?

<p>Reticular formation (D)</p> Signup and view all the answers

During REM sleep, muscle tone is increased, allowing for complex movements.

<p>False (B)</p> Signup and view all the answers

What hormone, produced by the pineal gland, plays a significant role in regulating circadian rhythms?

<p>melatonin</p> Signup and view all the answers

Jet lag is an example of a disruption to the ______ rhythm, caused by rapid translocation across time zones.

<p>circadian</p> Signup and view all the answers

Match the following types of biological rhythms with their approximate period.

<p>Ultradian = Less than 24 hours Circadian = Approximately 24 hours Infradian = More than 24 hours but less than 1 year</p> Signup and view all the answers

Which area of the cerebral cortex is primarily responsible for integrating sensory and motor information and is crucial for complex sensorimotor integration?

<p>Lateral posterior thalamic nucleus (D)</p> Signup and view all the answers

The anterior association area(prefrontal cortex) is primarily involved in basic sensory processing.

<p>False (B)</p> Signup and view all the answers

Damage to what specific brain region results in deficits in concentration, orientation, abstracting ability, judgement, and problem solving ability?

<p>anterior association area/prefrontal cortex</p> Signup and view all the answers

The planum temporale, linked to language processing, is often notably larger in the ______ hemisphere, particularly in right-handed individuals.

<p>left</p> Signup and view all the answers

Match the following aphasia types with their primary characteristic:

<p>Broca's aphasia = Difficulty producing speech Wernicke's aphasia = Difficulty understanding language Conduction aphasia = Intact comprehension but poor speech repetition</p> Signup and view all the answers

What term describes the act of being unable to recognize familiar faces, even though other aspects of visual processing and intellectual function remain intact?

<p>Prosopagnosia (B)</p> Signup and view all the answers

Apraxia is caused by sensory loss or paralysis.

<p>False (B)</p> Signup and view all the answers

What broad category of psychological states is based on physical sensations, biological reactions, and mental awareness, commonly associated with mood and motivation?

<p>emotions</p> Signup and view all the answers

Damage to what anatomical part of the brain can reduce complex emotional processing and organization?

<p>amygdala</p> Signup and view all the answers

Match the behavioral effects with their motivational component.

<p>Decision to begin a course of action = Activation Sustained efforts towards a goal = Persistence Dedication of energy and concentration towards a goal = Intensity</p> Signup and view all the answers

What component is NOT a consequence of addiction behavior?

<p>Control over substance or behavior (D)</p> Signup and view all the answers

Anterograde amnesia involves the loss of access to events that occurred prior to brain damage, while the ability to form new memories remains intact.

<p>False (B)</p> Signup and view all the answers

What name was given to the basic unit of functioning in the NS

<p>reflex</p> Signup and view all the answers

Exteroceptive learning happens due to ______ stimuli.

<p>external</p> Signup and view all the answers

Link learning types to their characteristics.

<p>Nonassociative Habituation = Repeated exposure to a stimulus causes reduced response Nonassociative Sensitization = Exposure to a stimulus causes a stronger response Associative classical conditioning = Neutral stimuli become associated with naturally occuring stimuli. Associative Operant conditioning = Behaviours become linked to both negative and positive reinforcement and punishment</p> Signup and view all the answers

Who observed dogs salivating with the sound of a bell which was originally presented with a meal?

<p>Pavlov (D)</p> Signup and view all the answers

Extinction learning refers to the addition of new behaviour from an unconditioned stimulus.

<p>False (B)</p> Signup and view all the answers

Systemic Desensitization is a form of therapy based on the conditioning that addresses what psychological challenge?

<p>phobias</p> Signup and view all the answers

Brain functions such as coding, storage and recalling of events would be best described as ______.

<p>memory</p> Signup and view all the answers

Match the memory types with their memory capacity and ability to retain information.

<p>Short Term Memory = Limited Capacity and only retain information for brief periods. Long Term Memory = Large capacity and can retain information over large periods.</p> Signup and view all the answers

What area of the brain is primarily responsible for long-term potentiation (LTP)?

<p>Hippocampus (C)</p> Signup and view all the answers

Learning is one key element to both habituation and sensitization in a subject.

<p>True (A)</p> Signup and view all the answers

Which of the following cell types are considered principal cell types of the nervous system?

<p>Neurons and Supporting cells (B)</p> Signup and view all the answers

Telodendria are the primary structures for receiving information in a neuron.

<p>False (B)</p> Signup and view all the answers

Which of the following is the primary function of the axon initial segment?

<p>Transmission of information away from the neuron body (B)</p> Signup and view all the answers

What structural characteristic defines bipolar neurons?

<p>Two processes extending from the cell body (one dendrite and one axon) (C)</p> Signup and view all the answers

Multipolar neurons constitute approximately 50% of the neurons in the nervous system.

<p>False (B)</p> Signup and view all the answers

Which of the following functional types of neurons typically carry impulses to the CNS?

<p>Sensory Neurons (A)</p> Signup and view all the answers

Which of the following describes divergence in neuronal connections?

<p>An axon diverges into multiple nerve endings, synapsing with several neurons (B)</p> Signup and view all the answers

In facilitation, the presynaptic neuron decreases the amount of released mediator.

<p>False (B)</p> Signup and view all the answers

Which of the following best describes recurrent inhibition?

<p>Collateral to an inhibitory interneuron suppressing a presynaptic neuron (C)</p> Signup and view all the answers

What is the role of glial cells relative to neurons?

<p>Provide support and insulation to neurons. (C)</p> Signup and view all the answers

Supporting cells are nonessential for the survival and function of neurons.

<p>False (B)</p> Signup and view all the answers

Which type of supporting cell myelinates neurons in the central nervous system (CNS)?

<p>Oligodendrocytes (D)</p> Signup and view all the answers

What is a primary function of Astrocytes?

<p>Maintain a stable chemical environment (C)</p> Signup and view all the answers

Astrocytes primarily electrical insulation of neurons

<p>True (A)</p> Signup and view all the answers

What is the role of astrocytes in potassium spatial buffering?

<p>To maintain stable extracellular $K^+$ levels, preventing interference with normal action potential propagation (B)</p> Signup and view all the answers

Which of the following describes the function of Schwann cells?

<p>Forming myelin sheaths around axons in the PNS (A)</p> Signup and view all the answers

Match the following components of the PNS with the appropriate description of their division:

<p>Somatic sensory = Sensory information from the skin and muscles Visceral sensory = Sensory information from internal organs Somatic motor = Motor control of skeletal muscles Autonomic motor = Motor control of smooth muscle, cardiac muscle, and glands</p> Signup and view all the answers

Signals are transmitted between the CNS and receptors and effectors via the ____.

<p>PNS</p> Signup and view all the answers

All cranial nerves contain afferent fibers.

<p>False (B)</p> Signup and view all the answers

The dorsal root ganglion contains what kind of neurons?

<p>sensory</p> Signup and view all the answers

In a spinal nerve, what type of information is carried by the ventral root?

<p>Motor information to muscles (B)</p> Signup and view all the answers

Match the cranial nerve with its function:

<p>Olfactory = Smell Optic = Vision Oculomotor = Eye movement, pupil constriction Vagus = Speech, swallowing, heart rate, stomach motility</p> Signup and view all the answers

The somatic nervous system (SNS) differs from the autonomic nervous system (ANS) because the SNS:

<p>uses a single neuron from the CNS to effector organs (A)</p> Signup and view all the answers

The sympathetic nervous system causes stimulatory effects on smooth muscle in the Smooth muscle (e.g., in gut), glands, cardiac muscle .

<p>False (B)</p> Signup and view all the answers

Which of the following is NOT part of the CNS?

<p>Cranial Nerves (D)</p> Signup and view all the answers

Within the spinal cord, the butterfly-shaped area consisting of interneurons, cell bodies of efferent neurons, entering axons of afferent neurons, and glial cells is called the ____ matter.

<p>grey</p> Signup and view all the answers

What is the functional significance of somatotopy in white matter pathways of the spinal cord?

<p>It allows precise spatial relationships between different body areas to be maintained in the transmission of information. (B)</p> Signup and view all the answers

The primary function of the brainstem is higher-order cognitive processing.

<p>False (B)</p> Signup and view all the answers

Which part of the diencephalon is responsible for neuroendocrine control, including regulation of hunger, thirst, and body temperature?

<p>Hypothalamus (D)</p> Signup and view all the answers

The thalamus integrates information and regulates transfer in only simple ways.

<p>False (B)</p> Signup and view all the answers

Which thalamic nucleus is a key relay between the inferior colliculus and the primary auditory cortex?

<p>Medial geniculate nucleus (A)</p> Signup and view all the answers

What areas do the Lateral posterior thalamic nucleus output to?

<p>superior parietal lobe - areas 5 and 7 (C)</p> Signup and view all the answers

The primary somatosensory area is located in ?

<p>Parietal lobe (C)</p> Signup and view all the answers

What is the basic functional unit of the nervous system?

<p>Reflex (A)</p> Signup and view all the answers

What is the correct order of elements in a reflex arch?

<p>receptor-&gt; afferent neuron-&gt; center-&gt; efferent neuron-&gt; effector (C)</p> Signup and view all the answers

Polysynaptic reflexes are characterized by several synapses in the reflex arch.

<p>True (A)</p> Signup and view all the answers

Cerebrospinal fluid (CSF) is produced in the

<p>choroid plexus (D)</p> Signup and view all the answers

Substances can cross the blood-brain barrier by following methods:

<p>all of the above (D)</p> Signup and view all the answers

Circumventricular organs have BBB.

<p>False (B)</p> Signup and view all the answers

The brain prefers using what energetic substance:

<p>Glucose (D)</p> Signup and view all the answers

The outer layer of the cerebral hemispheres is called

<p>grey matter (B)</p> Signup and view all the answers

Waveforms in a EEG represent summation of the ______ potentials from a large number of neurons

<p>postsynaptic</p> Signup and view all the answers

An EEG recording and assessment have what two main variables:

<p>Frequency and Amplitude (C)</p> Signup and view all the answers

Which type of EEG rhythms involves lower frequencies - less responsive behaviors (sleep)?

<p>delta (C)</p> Signup and view all the answers

Arousal and wakefulness - defined by the content of consciousness

<p>False (B)</p> Signup and view all the answers

Reticular Formation is for motor control.

<p>False (B)</p> Signup and view all the answers

All the followings are the component of Motivation, EXCEPT

<p>Stimulus (D)</p> Signup and view all the answers

Which of the following accurately describes the function of dendrites in a neuron?

<p>Receiving information from other neurons (C)</p> Signup and view all the answers

Bipolar neurons, characterized by having two processes (one dendrite and one axon), are the most common type of neuron in the nervous system.

<p>False (B)</p> Signup and view all the answers

What is the primary role of motor neurons in the nervous system?

<p>Transmitting impulses from the CNS to effectors</p> Signup and view all the answers

_________ summation involves the summation of postsynaptic potentials generated at different locations on the neuron.

<p>Spatial</p> Signup and view all the answers

What is the MAIN function of recurrent inhibition in neural circuits?

<p>Protecting neurons from excessive activity through feedback inhibition (D)</p> Signup and view all the answers

Astrocytes, a type of supporting cell in the nervous system, are considered non-essential for the survival and function of neurons

<p>False (B)</p> Signup and view all the answers

What is the role of oligodendrocytes in the central nervous system (CNS)?

<p>Myelination of CNS neurons</p> Signup and view all the answers

Astrocytes help maintain a stable environment for neurons, and play an important role in the ________, preventing harmful substances from entering the brain.

<p>BBB</p> Signup and view all the answers

Which of the following is a key function of Astrocytes regarding the concentration of $K^+$ in the extracellular fluid?

<p>Regulation of EC concentration of $K^+$ in the brain. (C)</p> Signup and view all the answers

Satellite cells form myelin sheaths around axons in the peripheral nervous system.

<p>False (B)</p> Signup and view all the answers

Match the cranial nerve with its associated primary function:

<p>Optic nerve = Vision Oculomotor nerve = Eye movements Vagus nerve = Heart rate, digestion Hypoglossal nerve = Tongue movement</p> Signup and view all the answers

What is the primary function of the spinal cord's white matter?

<p>Transmission of information between the brain and periphery</p> Signup and view all the answers

The _________ (above the optic chiasm) governs the secretion of melatonin and is strongly activated during sleep.

<p>suprachiasmatic nucleus</p> Signup and view all the answers

Which of the following characterizes Non-REM sleep?

<p>High amplitude and low frequency brain waves (B)</p> Signup and view all the answers

During REM sleep, muscle tone is markedly increased, allowing for significant physical movement.

<p>False (B)</p> Signup and view all the answers

What is the main characteristic of beta rhythms observed in EEG recordings?

<p>Alertness, CNS activity, REM sleep</p> Signup and view all the answers

_________ (loss of the ability to understand language) results in speak[ing] clearly [but] words that are put together make no sense.

<p>Wernicke's aphasia</p> Signup and view all the answers

Which of the following abilities is primarily associated with functions of the posterior association area?

<p>Analysis of spatial coordinates and language comprehension (A)</p> Signup and view all the answers

In classical conditioning, reinforcing a behavior involves presenting an unpleasant stimulus after that behavior occurs.

<p>False (B)</p> Signup and view all the answers

Match each stage of memory with its description:

<p>Encoding = Processing and combining of received information Storage = Creation of a permanent record Recall = Calling back the stored information</p> Signup and view all the answers

Which zone of the hypothalamus is primarily involved in complex autonomic responses and neuroendocrine control?

<p>Periventricular zone (D)</p> Signup and view all the answers

The suprachiasmatic nucleus, located in the anterior hypothalamus, is primarily involved in regulating biological rhythms.

<p>True (A)</p> Signup and view all the answers

Name two circumventricular organs through which the hypothalamus receives signals about blood composition.

<p>Area postrema, Organum vasculosum of the lamina terminalis (OVLT)</p> Signup and view all the answers

Which hypothalamic output to the autonomic nervous system (ANS) primarily regulates heart rate, vasoconstriction, digestion, and sweating?

<p>Lateral hypothalamus and para-ventricular nuclei projection to the lateral medulla (A)</p> Signup and view all the answers

Magnicellular neurosecretory systems, including the supraoptic and paraventricular nuclei, primarily produce the hormones __________ and ___________.

<p>oxytocin;vasopressin</p> Signup and view all the answers

Which of the following is the primary mechanism by which hormones from the hypothalamus reach the anterior pituitary gland?

<p>Portal circulation (D)</p> Signup and view all the answers

Homeostasis is maintained by the hypothalamus with a fixed set-point that never changes throughout an individual's life.

<p>False (B)</p> Signup and view all the answers

Name two effectors employed during thermoregulation mediated by the hypothalamus.

<p>blood vessels;sweat glands;shivering</p> Signup and view all the answers

During thermal sweating, what is the primary mechanism that eccrine sweat glands use to cool the body?

<p>Evaporation of water (D)</p> Signup and view all the answers

In the context of fever, bacterial products stimulate leukocytes to release IL-1, which then leads to the synthesis and release of _______ into the brain, ultimately increasing the hypothalamic temperature 'set-point'.

<p>PGE2</p> Signup and view all the answers

Which hormone, produced by white adipose tissue, conveys information to the hypothalamus about the amount of energy stored in fat and suppresses appetite?

<p>Leptin (A)</p> Signup and view all the answers

The lateral hypothalamus acts as a 'satiety center,' constantly restraining feeding and leading to weight loss when lesioned.

<p>False (B)</p> Signup and view all the answers

How does the hypothalamus integrate information about current physiological state and the set point to create a compensatory response?

<p>The hypothalamus computes the difference between current physiological state and set point.</p> Signup and view all the answers

Which region of the hypothalamus, when injected with orexigenic signals, leads to excessive feeding?

<p>Dorsomedial nucleus (D)</p> Signup and view all the answers

Regulation include body temperature, electrolyte and fluid balance,________ and _______.

<p>blood pressure;body weight</p> Signup and view all the answers

Match the following hypothalamic nuclei with their primary function:

<p>Paraventricular nucleus = Fluid balance, milk let-down, parturition, autonomic and anterior pituitary control Arcuate nucleus = Control of anterior pituitary, feeding Suprachiasmatic nucleus = Biological rhythms Ventromedial nucleus = Appetite, body weight, insulin regulation</p> Signup and view all the answers

Which division of the nervous system is responsible for the 'fight or flight' response?

<p>Sympathetic (C)</p> Signup and view all the answers

The somatic nervous system innervates inner organs, glands, and vessels.

<p>False (B)</p> Signup and view all the answers

Name the three divisions of the autonomic nervous system.

<p>sympathetic;parasympathetic;enteric</p> Signup and view all the answers

Which division of the autonomic nervous system facilitates 'rest and digest' functions?

<p>Parasympathetic (D)</p> Signup and view all the answers

The sympathetic nervous system is also known as the ___________ system, while the parasympathetic nervous system is referred to as the ____________ system.

<p>thoracolumbar;craniosacral</p> Signup and view all the answers

What is a primary function of the autonomic nervous system?

<p>Maintaining homeostasis (C)</p> Signup and view all the answers

The basic functional unit of the autonomic nervous system is a voluntary, conscious reflex.

<p>False (B)</p> Signup and view all the answers

Name two neurotransmitters involved in the viscerosensitive pathway of the autonomic nervous system.

<p>CGRP;substance P;VIP</p> Signup and view all the answers

In the sympathetic nervous system, where do axons of preganglionic neurons typically synapse?

<p>In the paravertebral or prevertebral ganglia (D)</p> Signup and view all the answers

In the autonomic nervous system, preganglionic neurons release the primary neurotransmitter ________ to stimulate postganglionic neurons.

<p>ACh</p> Signup and view all the answers

Which type of receptor mediates the production of an excitatory postsynaptic potential (EPSP) in autonomic ganglia by changing the permeability of the neuron's membrane?

<p>Nicotinic (N) receptors (D)</p> Signup and view all the answers

Sweat glands are innervated by sympathetic fibers that release norepinephrine.

<p>False (B)</p> Signup and view all the answers

What are the sweat glands innervated by sympathetic cholinergic fibers called?

<p>eccrine</p> Signup and view all the answers

What is the primary effect of stimulating alpha-1 (α1) adrenergic receptors?

<p>Vasoconstriction (B)</p> Signup and view all the answers

The sympathetic nervous system's effects are characterized as ----------- discharge, mobilizing the body for activity.

<p>mass</p> Signup and view all the answers

Which of the following effects is characteristic of parasympathetic activation?

<p>Increased GI motility (C)</p> Signup and view all the answers

During fight or flight Gl peristalsis is increased.

<p>False (B)</p> Signup and view all the answers

Which of the following describes M3 muscarinic receptors?

<p>pupillary sphincter m., ciliary m.) and GIT glands (M3) (A)</p> Signup and view all the answers

The function of the autonomic nervous system, a parasympathetic stim, bradycardia:

<p>⬇contractility,⬇excitability,⬇ velocity of conduction (A)</p> Signup and view all the answers

Match the following autonomic responses with the corresponding system:

<p>Increased heart rate = Sympathetic Miosis = Parasympathetic Ejaculation = Sympathetic Detrusor muscle contraction = Parasympathetic</p> Signup and view all the answers

What is a primary function of the enteric nervous system?

<p>Regulation of digestion (A)</p> Signup and view all the answers

During blood concentration falls, hypothalamus Osmoreceptors Blood and Dehydration are high

<p>False (B)</p> Signup and view all the answers

Name the two neuronal types in the Efferent two-neuron pathway

<p>preganglionic;postganglionic</p> Signup and view all the answers

Which of the following best describes the location of the hypothalamus in relation to other brain structures?

<p>Above the brainstem and below the thalamus (C)</p> Signup and view all the answers

The lateral zone of the hypothalamus is primarily responsible for complex autonomic responses.

<p>False (B)</p> Signup and view all the answers

Which hypothalamic zone is primarily involved in regulating biologic rhythms, homeostasis, and reproduction?

<p>medial zone</p> Signup and view all the answers

The suprachiasmatic nucleus receives fibers from the optic nerve and is crucial for regulating ______ rhythms.

<p>circadian</p> Signup and view all the answers

Match the circumventricular organs' function with the system or condition they monitor:

<p>Changes in osmolarity = Circumventricular organs Toxins in the blood = Circumventricular organs</p> Signup and view all the answers

Which of the following hypothalamic outputs directly influences the sympathetic nervous system, leading to diffuse sympathetic discharge and increased adrenal medullary secretion?

<p>Stimulation of lateral parts (HPA axis) (D)</p> Signup and view all the answers

Magnicellular neurosecretory systems in the hypothalamus primarily produce thyrotropin-releasing hormone (TRH) and prolactin-releasing hormone (PRH).

<p>False (B)</p> Signup and view all the answers

What is the primary method by which releasing factors from the hypothalamus reach the anterior pituitary lobe?

<p>portal circulation</p> Signup and view all the answers

The hypothalamus maintains the inner environment through its neuroendocrine role (via the pituitary gland), its influence on the ANS, and its influence on behavior via the ______ system.

<p>limbic</p> Signup and view all the answers

Match the hypothalamic nucleus with its primary function:

<p>Supraoptic nucleus = Fluid balance and milk let-down Ventromedial nucleus = Appetite, body weight, and insulin regulation</p> Signup and view all the answers

Which area of the brain contains neurons that are considered heat-losing and heat-promoting centers?

<p>Preoptic area (C)</p> Signup and view all the answers

Vasomotor responses, such as vasoconstriction and vasodilation, are ineffective at maintaining body temperature when the ambient temperature is significantly higher than body temperature.

<p>True (A)</p> Signup and view all the answers

What type of sweat glands primarily respond to sympathetic cholinergic stimulation?

<p>eccrine</p> Signup and view all the answers

During a fever, bacterial products stimulate leukocytes to release IL-1, which leads to the synthesis and release of ______ in the brain, elevating the hypothalamic temperature 'set-point'.

<p>pge2</p> Signup and view all the answers

Match the afferent mechanism with food intake regulation

<p>gut peptide hypothesis = Food intake lipostatic hypothesis = Food intake</p> Signup and view all the answers

Which of the following best describes the function of the ventromedial nucleus in relation to appetite?

<p>Constantly restrains feeding (D)</p> Signup and view all the answers

Leptin deficiency in animals typically leads to a decrease in body weight due to increased food intake.

<p>False (B)</p> Signup and view all the answers

What type of autonomic nervous system fibers innervate eccrine sweat glands?

<p>sympathetic cholinergic fibers</p> Signup and view all the answers

In the sympathetic nervous system, a mass discharge results in increased blood flow to active muscles and ______ blood flow to the gastrointestinal tract and kidneys.

<p>decreased</p> Signup and view all the answers

Match the statement with either sympathetic or parasympathetic nervous system.

<p>Activation leads to increased energy expenditure. = Sympathetic Nervous System Activation leads to conservation of energy = Parasympathetic Nervous System</p> Signup and view all the answers

Which type of neuron directly innervates skeletal muscles, enabling voluntary movement?

<p>Motor neurons (B)</p> Signup and view all the answers

Involuntary posture-regulating movements are categorized as motor activity according to will.

<p>True (A)</p> Signup and view all the answers

Which structure plays a vital role in selecting movement goals and strategy?

<p>Motor cortex (D)</p> Signup and view all the answers

The relaxation of skeletal muscles is caused by the _______ of motor neurons.

<p>inhibition</p> Signup and view all the answers

Match the motor neuron types with their functions:

<p>Alpha motor neurons = Innervate extrafusal muscle fibers for muscle contraction Gamma motor neurons = Innervate intrafusal muscle fibers and keep muscle spindles taut</p> Signup and view all the answers

Which of the following describes the motor neuron arrangement in the spinal cord according to the proximal-distal rule?

<p>Proximal muscles are innervated by medial motoneurons (B)</p> Signup and view all the answers

Propriospinal neurons form direct connections with afferent neurons exclusively.

<p>False (B)</p> Signup and view all the answers

What is the primary function of propriospinal neurons?

<p>Regulate voluntary and reflex motor acts (C)</p> Signup and view all the answers

La inhibitory interneurons are involved in the stretch reflex through _______ inhibition.

<p>reciprocal</p> Signup and view all the answers

Which of the following best defines the function of Renshaw cells?

<p>Modulate recurrent inhibition produced by other Renshaw cells (C)</p> Signup and view all the answers

Match the brainstem motor nuclei to their location:

<p>Medial motor nuclei = Close to the midline Lateral motor nuclei = Special visceral motor column</p> Signup and view all the answers

Which feature is NOT a key aspect in categorizing motor pathways?

<p>Timing of activation (D)</p> Signup and view all the answers

The vestibulospinal tract is part of the dorsolateral motor system.

<p>False (B)</p> Signup and view all the answers

Which tract is responsible for the control of skilled movements of the contralateral limbs?

<p>Lateral corticospinal tract (C)</p> Signup and view all the answers

The corticobulbar tract originates in the pyramidal cells of the primary motor cortex and terminates in the _______.

<p>brainstem</p> Signup and view all the answers

What is the main function of the rubrospinal tract?

<p>Influence of distal muscles and goal-directed limb movements (D)</p> Signup and view all the answers

In the ventromedial motor system, the rubrospinal tract is responsible for posture and balance

<p>False (B)</p> Signup and view all the answers

Central motor neuron (MN) terminals that make monosynaptic connections with motor neurons are associated with which of the following?

<p>Allowing for precise prehension (A)</p> Signup and view all the answers

A lesion in peripheral motor neurons leads to an inability of the muscle to _______.

<p>contract</p> Signup and view all the answers

Following an injury to a peripheral motor neuron's axon, which of the following cells promotes axon regrowth by providing a surface for the axon to grow along within the peripheral nervous system (PNS)?

<p>Schwann cells (C)</p> Signup and view all the answers

Match the term with the definition:

<p>Paresis = muscle weakness Paralysis = loss of movement</p> Signup and view all the answers

Which of the following terms defines the absence of reflexes?

<p>Areflexia (D)</p> Signup and view all the answers

Responses after spinal shock disappears involve sexual reflexes

<p>False (B)</p> Signup and view all the answers

In the context of reflex activity, what term is used to describe a normal response?

<p>Normoreflexia (D)</p> Signup and view all the answers

_______ reflexes are crucial for protection of the organism against harmful influences as well as reflexes causing muscle spasm.

<p>exteroceptive</p> Signup and view all the answers

Following a painful stimulus to one leg, what response occurs in the opposite leg during the crossed extensor reflex?

<p>Extension (A)</p> Signup and view all the answers

A polysynaptic reflex only has one synapse

<p>False (B)</p> Signup and view all the answers

What results from noxious plantar stimulation or tactile stimulation of the perianal skin following a spinal cord transection?

<p>Contraction of the anal sphincter (C)</p> Signup and view all the answers

Clinical examination of _______ reflexes is used to assess the integrity of the spinal cord and the corresponding reflex arcs.

<p>proprioceptive</p> Signup and view all the answers

For the patellar reflex, where should the neurological hammer be aimed?

<p>Patellar ligament (C)</p> Signup and view all the answers

Match the component of the reflex arc their description.

<p>Effector = The muscle fiber that contracts Receptor = Responds to the stimulus</p> Signup and view all the answers

What is the main function of the brain stem in motor control?

<p>Coordination of complex reflexes (C)</p> Signup and view all the answers

Muscle spindles increases muscle tone which inhibits gravity.

<p>False (B)</p> Signup and view all the answers

What is a motor consequence of decerebrate rigidity?

<p>Extension in all four limbs (B)</p> Signup and view all the answers

_______ muscles adjust subtle changes to help maintain balance.

<p>antigravity</p> Signup and view all the answers

Match the location with the correct definition

<p>Flocculonodular lobe = Location: VVestibulocerebellum Vermis = Location: sSpinocerebellum</p> Signup and view all the answers

What is a known component of the cerebrallar cortex?

<p>Highly folded (C)</p> Signup and view all the answers

What part of the cerbellum is important to motor learing?

<p>Climbing Fibre System (B)</p> Signup and view all the answers

Damage to what part of the cerebellum can cause wide stances?

<p>Spinocerebellum (D)</p> Signup and view all the answers

What is a main action of the Basal Ganglia?

<p>Cognition (D)</p> Signup and view all the answers

Athetosis would be a disorder of the subthalamic nc.

<p>False (B)</p> Signup and view all the answers

In the role of the prefontal cortex what decisions are converted to action?

<p>Eexecutive (D)</p> Signup and view all the answers

What is the primary function of the somatic nervous system?

<p>Controlling skeletal muscle movement (A)</p> Signup and view all the answers

Motor skills are solely determined by the activity of inner organs and glands.

<p>False (B)</p> Signup and view all the answers

Which of the following describes a voluntary motor activity?

<p>Intentional movement (A)</p> Signup and view all the answers

Relay station of motor programs is the ______

<p>thalamus</p> Signup and view all the answers

Match the following motor system components with their respective functions:

<p>Spinal Level (MNs) = Local patterns of movement Midbrain Level (BG, Cb) = Maintaining posture and equilibrium Motor cortex = Selecting movement goals and strategy</p> Signup and view all the answers

What is the role of the motor cortex in controlling body movement?

<p>Selecting movement goals and strategies (B)</p> Signup and view all the answers

In the control of voluntary movement, what is the function of central motor neurons?

<p>Transmitting signals from the brain to the spinal cord (D)</p> Signup and view all the answers

Peripheral motor neurons can directly relax muscles.

<p>False (B)</p> Signup and view all the answers

What is the function of gamma motor neurons?

<p>keep muscle spindles taut</p> Signup and view all the answers

Which motor neuron pool is responsible for controlling trunk posture and balance?

<p>Ventromedial MN pool (B)</p> Signup and view all the answers

According to the proximal-distal rule, motoneurons for proximal muscles are located laterally in the spinal cord.

<p>False (B)</p> Signup and view all the answers

What is the function of propriospinal neurons?

<p>Regulating voluntary and reflex motor acts (D)</p> Signup and view all the answers

Inhibitory interneurons that receive input from Ia afferents of muscle spindles are called ______ interneurons

<p>Ia inhibitory</p> Signup and view all the answers

Match the following spinal interneurons with their primary input:

<p>Ia inhibitory interneurons = Ia afferent of the muscle spindle Ib inhibitory interneurons = Golgi tendon organs Renshaw cells = Excitatory collateral from alpha-MNs</p> Signup and view all the answers

Where are alpha motor neurons that control muscles of the head and face localized?

<p>Localized in motor centers in the brainstem (B)</p> Signup and view all the answers

The corticobulbar tract controls movements of extremities.

<p>False (B)</p> Signup and view all the answers

Which motor pathway is responsible for posture and balance?

<p>Anterior corticospinal tract (A)</p> Signup and view all the answers

Which of the following is a feature of the lateral corticospinal tract?

<p>Controls fine movements of the digits (B)</p> Signup and view all the answers

Majority (90%) of central MNs terminate on ______

<p>interneurons</p> Signup and view all the answers

The only kind of input that goes to gamma motor neurons is direct input.

<p>False (B)</p> Signup and view all the answers

What is the main consequence of peripheral motor neuron lesion?

<p>Inability of the muscle to contract (D)</p> Signup and view all the answers

Following injury of peripheral MNs, axons have higher chance for regeneration in PNS or CNS?

<p>PNS</p> Signup and view all the answers

A reflex arc always involves the brain directly.

<p>False (B)</p> Signup and view all the answers

Match the component of the reflex arc with its action:

<p>Receptor = Receives the initial stimulus Afferent neuron = Transmits sensory information to the central nervous system Center = Processes information Efferent neuron = Carries motor command to effector Effector = Responds to the motor signal</p> Signup and view all the answers

Where do the sensory and motor components of a proprioceptive reflex occur?

<p>In the same muscle (A)</p> Signup and view all the answers

What is the function of mechanicaly-gated ion channels?

<p>To transmit afferent signals (B)</p> Signup and view all the answers

The primary endings in muscle spindles sends signal to the spinal cord with the help of ______ afferents.

<p>Ia</p> Signup and view all the answers

In a myotatic reflex, muscle contraction occurs in response to the shortening of that muscle.

<p>False (B)</p> Signup and view all the answers

What is the main mechanism by which muscle spasms occur as a result of spinal cord reflexes?

<p>Extreme stimulation of pain receptors (B)</p> Signup and view all the answers

What is the main function of inverse myotatic reflex?

<p>Muscle relaxes (B)</p> Signup and view all the answers

After spinal cord transection above the limb segments, the crossed extensor reflex results in:

<p>Stimulus supports body as weight shifts away (B)</p> Signup and view all the answers

All of the following are examples of exteroceptive reflexes, EXCEPT:

<p>flexor withdrawal reflex (D)</p> Signup and view all the answers

Lesions to the spinal cord at segments L2-L4 will affect which of the following reflexes?

<p>Patellar reflex (D)</p> Signup and view all the answers

The function of alpha-gamma coactivation is:

<p>Sensory neurons then discharge when the muscle is stretched (C)</p> Signup and view all the answers

Where is the spinal intermediate zone located?

<p>laminae V-VIII</p> Signup and view all the answers

The term Areflexia describes long term excitiation of spinal reflexes.

<p>False (B)</p> Signup and view all the answers

Which of the following is NOT included in the postural regulation by the motor parts of the brain stem?

<p>blood pressure (C)</p> Signup and view all the answers

Which stimulus causes magnet reaction?

<p>contact with sole</p> Signup and view all the answers

The flocculonodular lobe is ontogenetically first.

<p>True (A)</p> Signup and view all the answers

As a function, what role does the motor cortex serve?

<p>voluntary action (D)</p> Signup and view all the answers

Which of the following is a primary function of the somatic nervous system?

<p>Controlling skeletal muscle movement (C)</p> Signup and view all the answers

Skeletal muscles are innervated by the efferent portion of the autonomic nervous system.

<p>False (B)</p> Signup and view all the answers

What type of efferent neurons directly stimulate muscle contraction?

<p>Motor neurons</p> Signup and view all the answers

The type of movement that is purposeful and goal-directed is known as __________ movement.

<p>Voluntary</p> Signup and view all the answers

Match the classes of movement with their respective descriptions:

<p>Reflex responses = Stereotyped, involuntary movement initiated by a stimulus Rhythmic, repetitive motions = Sequence of relatively stereotyped and almost automatic voluntary movements Voluntary movement = Purposeful, goal-directed, complex, learned movements</p> Signup and view all the answers

At which level of the neural system organization does most of the activating motor signals reach the spinal cord?

<p>Motor Cortex (C)</p> Signup and view all the answers

What anatomical structure houses the motor neuron pool which contains all the motor neurons that innervate a single muscle?

<p>Ventral horn</p> Signup and view all the answers

The two types of motor neurons are alpha and __________ motor neurons.

<p>gamma</p> Signup and view all the answers

Match the motor neuron pool to the body area it controls:

<p>Dorsolateral MN pool = Voluntary movement of the extremities, particularly the hands Ventromedial MN pool = Controls the trunk (posture and balance)</p> Signup and view all the answers

According to the proximal-distal rule, motoneurons for distal muscles are located where in relation to the spinal cord?

<p>Lateral (D)</p> Signup and view all the answers

Propriospinal neurons only transmit information from the periphery to motor neurons.

<p>False (B)</p> Signup and view all the answers

In what spinal cord laminae are propriospinal neurons located?

<p>V-VIII</p> Signup and view all the answers

Ia inhibitory interneurons primarily mediate the principle of __________ inhibition, essential for coordinating agonist and antagonist muscles.

<p>reciprocal</p> Signup and view all the answers

Match the type of spinal interneuron with its function:

<p>Ia inhibitory interneurons = Involved in the stretch reflex; mediate reciprocal inhibition Ib inhibitory interneurons = Involved in autogenic inhibition reflex; coordinate extensor and flexor muscles Renshaw cells = Control the level of excitation of motor neurons and mediate recurrent inhibition</p> Signup and view all the answers

Peripheral motor neurons of the brainstem exist in two longitudinal columns; what are they?

<p>Medial and Lateral (C)</p> Signup and view all the answers

The corticobulbar tract controls voluntary movement of the limbs

<p>False (B)</p> Signup and view all the answers

The vestibulospinal tract, which is part of the ventromedial motor system, is primarily involved in the control of __________ and balance.

<p>posture</p> Signup and view all the answers

Match the motor system's tracts with where the spinal projection ends:

<p>Dorsolateral System = Lateral column Ventromedial System = Ventral column</p> Signup and view all the answers

Flashcards

Nervous System Cell Types

Two principal cell types of the nervous system are neurons and supporting cells.

Neuron Structural Differences

Structural differences among Neurons are based on the number of processes extending from the cell body, creating types like bipolar, multipolar, and unipolar neurons.

Neuron Functional Differences

Functional differences among neurons include sensory neurons (afferent), interneurons (link neurons), and motor neurons (efferent).

What are Supporting Cells?

Supporting cells are non-excitable cells essential for the survival and function of neurons, comprising half the nervous system's volume.

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Astrocytes

Astrocytes in the CNS maintain a stable environment for neurons, aiding in metabolism and insulation.

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PNS Supporting Cells

Peripheral Nervous System supporting cells include Schwann cells (myelin sheath formation) and satellite cells (regulate chemical environment).

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Reciprocal Innervation

Reciprocal innervation is a process involving simultaneous agonist activation and antagonist inhibition to control movement.

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Afferent Division (PNS)

The Afferent division of the PNS carries sensory information to the CNS, split into somatic, visceral, and special sensory.

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Efferent Division (PNS)

The Efferent division of the PNS transmits motor commands from the CNS to effectors.

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Central Nervous System

Composed of the brain and spinal cord, it integrates and processes information to coordinate bodily activity.

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Grey Matter

Within the spinal cord it is typically butterfly shaped and contains interneurons, cell bodies of efferent neurons, and axons of afferent neurons.

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White Matter

Structure in the spinal cord consisting of myelinated fiber tracts that transmit signals, divided into columns.

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Somatotopy

A principle that explains that most exhibit precise spatial relationships in the white matter tracts in the spinal cord.

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Brainstem Function

The brainstem contains medulla, pons, and midbrain structures used for visceral control centers.

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Diencephalon

Contains the thalamus and hypothalamus structures.

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Thalamus Functions

The thalamus relays sensory and motor signals and regulates alertness.

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Reflex action

A reflex is response of organism to receptor stimulation facilitated by a reflex arc.

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Reflex Arc Components

The receptor, afferent neuron, center, efferent neuron, and effector make up the reflex arc.

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Cerebrospinal Fluid (CSF)

The cerebrospinal fluid (CSF) is a clear, colorless fluid that surrounds and bathes the CNS, providing protection and maintaining the chemical environment.

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Blood-Brain Barrier (BBB)

The barrier's function is to prevent blood borne metabolic wastes, proteins, toxins, and most drugs from entering brain tissue..

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Circumventricular Organs

Describes areas lacking a blood-brain barrier which allows for regulation and secretions

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What does the term EEG stand for?

The term that is applied to the recording of the brains electrical activity

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Delta Rhythm

The term EEG that represents deep sleep

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Arousal and Wakefulness

The term which describes being at full alertness

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Sleep

This describes a normal cyclic physiological alteration of consciousness from which a person can be aroused by sensory stimuli.

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Non-REM Sleep

Non-REM consists of slow-wave sleep without rapid eye movements. High amplitude and low frequency .

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REM Sleep

REM Sleep is a an active sleep stage with rapid eye movements, muscle tone reduction, .

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Biological Rhythms

Biological rhythms are cyclic changes of biological functions, synchronized with external environment.

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Melatonin

Hormone released from the pineal glad that is increased at night this is associated with sleep.

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Cognition

A broad term of the brain's higher-level mental processes and include memory, perception, attention, learning and language.

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Anterior Association Area

Area in the brain responsible for thinking about abstract ideas, judgements, and decision making.

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Posterior Association Area

Area in the brain responsible for the processing of the body's spatial coordinates.

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Prosopagnosia

A disorder that is characterized by impairments with the ability to indentify people's faces.

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What is aphasia?

Describe Language disorders

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Aprosodia

Inability to properly express and/or comprehend prosody (melodic aspects of speech)

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Learning disabilities

An inherited, neurodevelopmental speceilized learning disorder. For example: dyslexia.

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Dyslexia

Difficulty with reading comprehension

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Agraphia

Inability to reproduce written words

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What are Emotions?

A subjective, conscious experience characterized by psychophysiological expressions, biological reactions, and mental stated

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Amygdala

The Amygdala processes novel stimuli of emotional significance and learning

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Amygdala Hippocampus

Is related to that person reacting in an irrational and destruction way because the amygdala perceives a treat

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What are Instincts

Motivation groups or Instincts are are an inherent inclination of an organism towards a particualr complex behaviour that is similar for each member of that species.

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What is learning?

An Enduring change in behavior from experience

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What is Habituation

A Learning which consists of Repeated stimulus becomes progressively less important

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What is Sesitization

A A type of learning which involves repeated stimulus becomes progressively more important

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What is Classical conditioning

A learning which consists of neutral stimulus becoming associated with a biologically potent simulus

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Categories of memory

What Describes short-term and long-term memory (Declarative and procedural)?

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Implicit learning

What Describes memory that can not be recalled, a form of Procedural learning

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Conditioning

To alter behaviour with a reward to make sure behaviour is enforced

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Amnesia

Term discribing a loss of memory

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What is the hypothalamus?

A small area of the brain, about the size of an almond, located above the brainstem and below the thalamus.

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What are the hypothalamic nuclei?

The number and organization of small groupings of nerve cell bodies within the hypothalamus.

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What are the periventricular, medial, and lateral zones?

The hypothalamus is divided into these three zones.

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What is the periventricular zone?

This hypothalamic zone is involved in complex autonomic responses and neuroendocrine control.

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What is the lateral zone?

This hypothalamic zone influences arousal mechanisms and motivated behavior.

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What is the medial zone?

This hypothalamic zone is responsible for biologic rhythms, homeostasis and reproduction.

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What is the paraventricular/supraoptic nucleus?

This nucleus controls fluid balance, milk let-down, and parturition.

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What is the arcuate nucleus?

This nucleus regulates the anterior pituitary and feeding behavior.

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What is the anterior nucleus?

This nucleus regulates thermoregulation and sexual behavior.

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What is the suprachiasmatic nucleus?

This nucleus regulates biological rhythms.

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What is the dorsomedial nucleus?

Stimulation of this nucleus results in rage/strong emotions.

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What is the ventromedial nucleus?

This is a satiety center that regulates appetite, body weight, and insulin regulation.

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What is the mammillary nucleus?

This nucleus is involved in emotion and short-term memory.

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What is the posterior nucleus?

This nucleus plays a role in regulating body temperature.

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What is the nucleus of the solitary tract?

The nucleus receives sensory information from blood pressure, gut distension, and the vagus nerve.

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What is the reticular formation?

This input informs the hypothalamus about skin temperature.

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What is the retina?

This input relays circadian rhythms and couples the rhythms to the light/dark cycles.

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What do circumventricular organs detect?

Change of osmolarity and toxins in blood.

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What is the limbic and olfactory system

What system involves subcortical parts of the limbic system, regulates behavior like regulating eating and reproduction

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To the ANS

Lateral hypothalamus and paraventricular nuclei project to the lateral medulla and SC, regulating heart rate, digestion, etc.

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To the posterior pituitary

Axons around the third ventricle release oxytocin and vasopressin.

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What are regulatory hormones?

Parvicellular neurosecretory systems secrete regulatory hormones. Name them.

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What is portal circulation?

Releasing factors from the hypothalamus to the anterior pituitary lobe.

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What is axonal transport?

Hormones from the hypothalamus to the posterior pituitary lobe.

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What is homeostasis?

The body's inner temperature control

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What is the preoptic area?

This area contains heat-losing and heat-promoting centers.

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What makes up the body's core?

Brain, heart, liver, kidney, spleen, and GIT measured around 37C.

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Shell

Skin, muscle, fat, and testes around 20-40C.

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How to activate heat losing mechanisms

Vasodilatation of skin arterioles, sweating, increased respiration, and behavioral adaptations.

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How to activate heat production mechanisms

Vasoconstriction of skin arterioles, shivering, and behavioral adaptations.

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What is adaptation to the heat?

This leads to improved salt conservation through decreased sweat [Na] and [Cl].

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What is the purpose of a fever?

Adaptive physiological response to infections.

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What is the hypothalamus in osmoregulation?

This structure monitors water concentration in the blood and stimulates thirst and ADH release.

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Food intake

General maintains of the weight at a given set point

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Suprachiasmatic nucleus

The drive to eat is evoked by appetite or the sensation of hunger

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Energy Balance

Lateral hypothalamus is the start of eating, ventromedial hypothalamus is stop the eating

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What functions are suppressed by Leptin

Appetite and energy expenditure are suppressed

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What is the action of Insulin

Promotes transport of glucose, stimulates uptake of glucose, decreases release of glucose AND decreases food intake.

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What are the two Autonomic divisions?

Sympathetic system = Thoracic Lumbar (fight or flight), Parasympathetic system = Cranial Sacral (rest or digest).

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What is the Efferent Divison?

Somatic motor, autonomic motor

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What the Autonomic Nervous System

Sympathetic, parasympathetic, and enteric are controlled by the:

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Axons and passing

The axons of preganglionic sympathetic neurons pass to the paravertebral ganglion and synapse, pass without synapsing, or leave to prevertebral ganglion.

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Rest and Digest

Discrete control of individual target tissues, excitation of GIT, slowing of heart

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Activation of the Sympathetic

This activates fight or flight, large portion of the sympathetic, and saves life

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M1, 3, and 5

Nerves, glands, smooth muscle, CNS

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M2 and 4

Heart and CNS

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Somatic Nervous System

The part of the nervous system associated with skeletal muscle motor neurons.

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Motor Neurons

Neurons that generate signals to control muscle activity.

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Response to Situation

The organism's reaction to its current environment.

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Skeletal Muscles

Skeletal muscles are effectors innervated by the efferent portion of the nervous system.

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Motor Skill Definition

Basic bodily movements to uphold life

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Motor Skills

Skills required for living, from basic action to complex coordination

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Activity By Skeletal Muscles

Movement caused by action of the somatic nervous system

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Motor Activity Scope

Includes voluntary, postural, and intentional tasks.

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Reflex responses

Movement type triggered by stimuli.

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Rhythmic, repetitive motions

Stereotyped movements like walking.

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Voluntary Movement

Purposeful motion, such as throwing a ball

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Spinal Level

The point in the nervous system where Local movement patterns occur.

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Midbrain Level

The nervous system location that is responsible for axial tone and equilibrium.

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Motor Cortex

The portion in the nervous system responsible for movement strategy.

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Central Motor Neurons

Motor control system component of nerve cells in the brain

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Peripheral Motor Neurons

Motor control system component nerves existing cranial nerves

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Extrafusal Muscle Fibers

α-MNs innervate these muscle fibers

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Intrafusal Muscle Fibers

γ-MNs innervate these muscle fibers.

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Dorsolateral MN Pool

Pool controlling extremities, manipulation.

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Ventromedial MN Pool

Pool controlling posture and balance.

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Propriospinal Neurons

These connect with afferent neurons and other neuronal groups in the spinal cord.

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Spinal Interneurons

These relay afferent and central patterns to motoneurons to control movement

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Ia Inhibitory Interneurons

Spinal interneurons inhibiting alpha motor neurons

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Ib Inhibitory Interneurons

Spinal interneuron activated by Golgi tendon organs and cutaneous receptors

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Renshaw Cells

Inhibitory interneurons regulating a-MN excitation.

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Medial MNs

Closer to the body's midline.

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Lateral MNs

Away from the body's midline.

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Trajectory of Axons

Path axons follow from origin to target.

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Ventromedial Motor System

Motor system controlling posture.

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Dorsolateral Motor System

Motor system controlling fractionated movement.

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Medial Brain Stem pathways

It is responsible for descending motor tracts coordinating axial muscles in ventromedial spinal cord.

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Anterior Corticospinal Tract

Motor impulses to axial muscles

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Lateral Corticospinal Tract

Controls MNs and interneurons.

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Corticobulbar Tract

Controls neck and head movement.

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Rubrospinal Tract

Influencer of distal muscles and goal-directed movement.

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VentroMedial System

Posture, and balance

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Dorsolateral System

Movement of limbs

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Central MN Termination

This includes 90% to the spinal connections

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Influence of Higher Centers

Spinal activation changes to higher function

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Final Common Pathway

MNs receiving inputs from receptors and brain.

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Peripheral MN Syndrome

Nerve damage causes muscle paralysis or paresis.

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Damages to Peripheral nerves and repair

When the body repair the damage to outside of the central nervous system

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Injuries and regeneration

Axon degenerates and then repair

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Neural stem cells

New solutions for fixing damage

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Myotatic Reflex

Muscle reflex in stretching of muscles.

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Muscle Spindle Function

Changes muscle length.

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Alpha gamma co activation

Ends with change in muscles

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Study Notes

Hypothalamus: Structure

  • Contains small nuclei.
  • Approximately the size of an almond.
  • Positioned above the brainstem and below the thalamus.

Hypothalamus: Zones

  • The Periventricular Zone moderates complex autonomic and neuroendocrine functions.
  • The Lateral Zone mediates arousal mechanisms and motivated behavior.
  • Biologic rhythms, homeostasis, and reproduction are regulated by the Medial Zone.

Hypothalamic Nuclei & Functions

  • The Paraventricular Nucleus is located in the anterior and tuberal regions, within the periventricular zone. It is involved in fluid balance, milk let-down, parturition, autonomic, and anterior pituitary control.
  • The Arcuate Nucleus, is located in the tuberal region, within the periventricular zone, controls anterior pituitary and feeding.
  • The Anterior Nucleus, controls thermoregulation and sexual behavior. It is within the medial zone and is located in the anterior region.
  • The Suprachiasmatic Nucleus is located in the medial zone. It is located in the anterior region and regulates biological rhythms.
  • The Dorsomedial Nucleus, controls emotion (rage). It is located in the tuberal region, within the medial zone.
  • The Ventromedial Nucleus, which controls appetite, body weight, and insulin regulation. It is located in the tuberal region, within the medial zone.
  • Emotion and short-term memory are managed by the Mammillary Nucleus. It is located in the posterior region, within the medial zone.
  • The Posterior Nucleus, which controls thermoregulation. It is located in the posterior region, within the medial zone.
  • Fluid balance, milk let-down, and parturition are controlled by the Supraoptic Nucleus. It is located in the anterior region, within the lateral zone.
  • The Preoptic Nucleus controls thermoregulation and sexual behavior. It is located in the anterior region, within the lateral zone.
  • Appetite and body weight are managed by, Lateral Complex (Tuberales). It is located in the tuberal region, within the lateral zone.

Hypothalamic Inputs

  • Visceral sensory information from the vagus nerve (blood pressure, gut distension) is received by the Nucleus of the Solitary Tract.
  • Information about skin temperature and variety of inputs from the spinal cord is received by the Reticular Formation.
  • A portion of the optic nerve's fibers go to the suprachiasmatic nucleus, which regulates circadian rhythms and couples them to light/dark cycles.
  • Osmolarity and toxins detection is managed in Circumventricular Organs.
  • Physical components of emotions (heart rate, blood pressure, sweating) and behaviors like eating and reproduction is regulated by Limbic and Olfactory Systems. Subcortical input comes from the limbic system (amygdala, hippocampus, olfactory cortex.)

Hypothalamic Outputs

  • Heart rate, vasoconstriction, digestion, and sweating are regulated where, Lateral hypothalamus and paraventricular nucleus project to the lateral medulla (parasympathetic vagal nuclei and cells descending to the sympathetic system in SC).
  • Diffuse sympathetic discharge and adrenal medullary secretion happens, stimulation to Lateral hypothalamus.

Hypothalamic: Endocrine Signals

  • Oxytocin and vasopressin are released by axons of large hypothalamic cells around the third ventricle, projecting to the posterior pituitary.
  • Factors to the anterior pituitary travel from smaller cells release within the same area.

Hypothalamic: Neuroendocrine Control

  • Oxytocin and vasopressin are produced by Magnicellular Neurosecretory Systems, located in the supraoptic and paraventricular nuclei
  • Regulatory hormones are produced, by Parvicellular Neurosecretory Systems, located in the paraventricular and arcuate nuclei, and medial preoptic area.
  • Regulatory hormones are;
  • Thyrotropin-releasing hormone (TRH, TRF)
  • Prolactin-releasing hormone (PRH)
  • Growth hormone releasing hormone (GHRH)
  • Somatostatin growth hormone inhibiting hormone (GHIH) – inhibits growth hormone and TSH
  • Gonadotropin-releasing hormone (GnRH or LHRH) – stimulates follicle-stimulating hormone and luteinizing hormone
  • Corticotropin-releasing hormone (CRH or CRF)

Hormone Secretion: Mechanisms

  • Releasing factors travel from the hypothalamus to the anterior pituitary lobe, via Portal Circulation.
  • Hormones travel from the hypothalamus to the posterior pituitary lobe, via Axonal Transport.

Hypothalamus and Homeostasis.

  • Via influence on the ANS (which is managed in the pituiatry gland), and behavior (limbic system) the inner environment is maintained.
  • Body temperature, electrolyte and fluid balance, blood pressure, and body weight is regulated.
  • The body provides compensatory changes for things that differ from the set-point.
  • Remarkably fixed, the set-point can migrate but it remains from day-to-day

Thermoregulation.

  • Preoptic area neurons as heat-losing (heat-promoting center) components.
  • Information from Thermoreceptors provides in terms of body temperatures.
  • The process runs in Negative feedback loops via body.

Thermoregulation: Components.

  • Core, is consisted the brain, heart, liver, kidney, spleen and GIT. It's measured around 37°C in the rectum, mouth or ear measuring points, varies to measure cooler at night.
  • Muscle, fat, skin and testes are described within the, Shell which usually measures, about 20-40°C

Thermoregulation responses.

  • A body holds the body temperature under this methods:
    • Vasomotor responses
    • Evaporative responses (above 30° ambient)
    • Metabolic responses (below 23° ambient)

Heat-Losing Center Mechanisms

  • Activation by various factors which
    • Vasodilatation of skin arterioles
    • Sweating
    • Increased respiration through mouth
    • Behavioral adjustments
  • Balance is maintained by Inhibiting, to stop heat-promoting center .

Heat-Promoting Center Mechanisms

  • Activation by various factors which
    • Vasoconstriction of skin arterioles
    • Shivering and non-shivering thermogenesis
    • Behavioral adjustments
  • Reabsorbs NaCl and bicarbonate to minimize whole-body balance balance. Which can be controlled by the stop of, Inhibiting stop heat-promoting center .

Thermal Sweating: Eccrine Sweat Glands

  • Heat is transfer from the body water on the surface of the skin, this action is done from Eccrine sweat glands
  • Sympathetic cholinergic stimulation
  • From initial response - rapid increase in sweat gland recruitment, to sweat secretion improvements in the, adaptation after being exposed to heat factors.
  • They are also responsive due to thermal stimuli and to non-thermal stimuli to exercise or stimuli for improvements in salt conservation to lower sweat levels etc.

Fever Response

  • Fever is the elevation of body temperature in response to the disease.
  • Thermoregulation problems exist, but Adaptive physiological occurs to to resolve bacteria in such infections. -bacterial products leads to the synthesis and release of PGE2 into the brain and causes signals that lead to the fever.
  • releases of IL-1 by leukocytes. --PGE2 induces the release of cAMP that causes a hypothalamic temperature ‘set-point’ to cause fever.

Osmoregulation (Water Metabolism) .

  • This process regulates water in the body.
    • Colon absortion happens due to lack of of colon water intake absorption.
      • This then causes less urine
  • This causes an over compensation to get water levels back to normal.

Food Intake Controls

  • Manage in terms of levels of both food hunger or thirst levels as a whole.

Orexigenic/Anorexigenic Neurotransmitters:

  • To Increase appetite take Orexigenic neurotransmitters. -To Decrease appetite stop eating, under way to Anorexigenic neurotransmitters
  • This then affects the way that we can balance weight , to maintained base that is at the given weight. -Meal time = base -Lipostatatic -Gut and pep -Therm
  • Gluc level

Hypothalamic Nuclei and Appetite

  • The Ventromedial Nucleus is also a 'satiety center' this center constantly restrains against of the current feeding. To do this it would trigger a weight reduction if weight gain was high, and when in the instance there is lesions leads to excessive appetite and abnormal body weigh gain
  • To prepeare peptides to do some orexigenic actions Arcuate Nucleus at the base of the hypothalamus for NPY, Dynophin (B), GABA, Glutamate.
  • Dorsomedial Nucleus helps leads to injections of orexigenic signals causing excessive feed intake.
  • Inject with anorexigenic signals and CRHa dn leptin in the and reduces the amount of lower/ingest the feeding.
    • The Paraventricular/Perifornical Nuclei controls Ingestive behavior by doing action with orexigenic/anorexigenic signals.
  • The Light-dark cycle and perception helps evoke by appetite/ hunger.
    • This affect the Suprachiasmatic Nucleus.

Hypothalamic Energy Balance

  • The lateral hypothalamus ('start eating,' = feeding center) and the ventromedial hypothalamus ('stop eating') centre maintain energy balance by dictating how much food will occur to be reiquired.

Leptin

  • Satiety factor ,studied extensively.
  • Dominately predominates that adipocytes synthetise and secretes
  • The increase of Leptin, is also major factor to the Leptin receptors hypothalamus.
  • injection with leptin into leptin-deficient animals, it causes a to suppression and causes reduction due to increase energy output. -Plasma helps rise and fall during content that causes body change and helps affect body fat mass.

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