Estrogens and Hormone Replacement Therapy
12 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the primary advantage of using nonoral estrogens?

  • They have a higher risk of deep vein thrombosis
  • They avoid first pass metabolism and result in a more physiologic estradiol : estrone ratio (correct)
  • They are more effective in treating urogenital atrophy
  • They are only available in transdermal dosage forms

What is the main component of conjugated equine estrogens?

  • Ethinyl estradiol
  • 17α-dihydroequilin
  • Estrone sulfate (correct)
  • Estradiol

What is the effect of oral estradiol on estrone concentrations?

  • It increases estrone concentrations three to six times (correct)
  • It reduces estrone concentrations to half
  • It completely eliminates estrone
  • It has no effect on estrone concentrations

What is the result of using transdermal estrogen dosage forms?

<p>A decrease in sex hormone–binding globulin, triglycerides, and blood pressure (A)</p> Signup and view all the answers

What is the indication for Femring?

<p>Moderate to severe vasomotor symptoms (B)</p> Signup and view all the answers

What is the trend in recent evidence regarding estrogen doses?

<p>Lower doses of estrogens are effective in controlling postmenopausal symptoms and reducing bone loss (A)</p> Signup and view all the answers

What is a common adverse effect of estrogen therapy?

<p>Nausea (D)</p> Signup and view all the answers

Which type of estrogen therapy is less likely to cause breast tenderness and gallbladder disease?

<p>Transdermal estrogen (C)</p> Signup and view all the answers

What is a contraindication for MHT?

<p>Personal history of breast cancer (C)</p> Signup and view all the answers

What is the increased risk associated with combined oral MHT containing estrogen and progestogen?

<p>Venous thromboembolism and stroke (D)</p> Signup and view all the answers

What is the effect of estrogen alone on endometrial cancer risk in individuals with an intact uterus?

<p>Increases the risk (C)</p> Signup and view all the answers

What is the effect of combined estrogen and progestogen therapy on dementia in postmenopausal individuals 65 years or older?

<p>Increases the risk (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser