Hormone Replacement Therapy and Breast Cancer Risk Quiz

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What is the structural analogue of spironolactone?

Levonorgestrel

Desogestrel

Drospirenone (correct)

Norethindrone

Which of the following is a C-19 progestin with anti-androgenic activity?

Drospirenone (correct)

Norelgestromin

Norethindrone

Norgestimate

What is the main mechanism of action of Clomiphene citrate?

Estrogen receptor antagonist

GnRH agonist

LH agonist

FSH inhibitor (correct)

Which C-19 progestin has minimal or no overall androgenic side effects?

Drospirenone Signup and view all the answers

How do hormonal contraceptives like birth control pills affect FSH and LH release from the pituitary?

Decrease FSH and LH release Signup and view all the answers

What is the main reason why estrogen is used alone should be given in a cyclic administration?

To mimic natural hormone fluctuations Signup and view all the answers

In what condition should estrogen therapy be used in combination with progesterone?

Primary hypogonadism Signup and view all the answers

Which hormone replacement therapy is increasingly discouraged in postmenopausal women due to increased risks of breast cancer and cardiovascular events?

Combination of estrogen and progesterone Signup and view all the answers

What is the primary function of continual administration of combination estrogen/progestin oral contraceptives for acne?

Decreases ovarian androgen synthesis Signup and view all the answers

Which condition does estrogen primarily target by inhibiting bone resorption but not stimulating new bone synthesis?

Post-menopausal osteoporosis Signup and view all the answers

What is the mechanism of action of drugs that block the production of ovarian-stimulating hormones?

Lower estrogen levels Signup and view all the answers

Which drug can relieve endometriosis signs and symptoms by halting menstrual periods and the growth of endometrial implants?

Depo-Provera Signup and view all the answers

Which type of C-19 progestins has anti-androgenic activity?

Drospirenone Signup and view all the answers

What is the concern related to the duration of therapy limitation for GnRH agonists in treating pelvic pain caused by endometriosis?

Significant bone loss Signup and view all the answers

Which contraceptive method can help inhibit endometrial tissue growth by causing initial decidualization and then atrophy?

Intrauterine device with levonorgestrel (Mirena) Signup and view all the answers

How do combination oral contraceptives help reduce dermatological manifestations in women with PCOS?

By inhibiting gonadotropin secretion and ovarian androgen secretion Signup and view all the answers

Which enzyme is more commonly known as 'Aromatase'?

CYP19 Signup and view all the answers

What is one of the overall goals of therapy for women with PCOS?

To prevent endometrial hyperplasia and carcinoma Signup and view all the answers

How do high and low GnRH pulse frequencies affect LH and FSH release, respectively?

Low GnRH pulse frequencies favor LH release Signup and view all the answers

Which medication is commonly used for ovulation induction in women pursuing pregnancy?

Clomiphene citrate Signup and view all the answers

Which class of enzymes is important in the growth and implantation of ectopic endometrium?

Matrix metalloproteinases Signup and view all the answers

Which medication acts as an antagonist at estrogen receptors in the breast but a partial agonist at estrogen receptors in the endometrium and bone?

Tamoxifen Signup and view all the answers

Which drug is primarily used for the treatment of breast cancers that are estrogen receptor-positive?

Toremifene Signup and view all the answers

Which medication is a structural analogue of spironolactone?

Drospirenone Signup and view all the answers

Which type of progestins have minimal or no overall androgenic side effects?

C-19 Progestins with anti-androgenic activity Signup and view all the answers

Which contraceptive method involves inserting a T-shaped piece of plastic that releases the progestin levonorgestrel?

IUD Signup and view all the answers

Which contraceptive method contains ethinyl estradiol and norelgestromin in a patch form?

Patch Signup and view all the answers

Which contraceptive method involves capsules of etonorgestrel placed under the skin for slow release up to 3 years?

Subdermal implant Signup and view all the answers

Which contraceptive method is reusable for one year and consists of segesterone and ethinyl estradiol?

Annovera® Signup and view all the answers

Which contraceptive method is administered as an injection every 3 months and contains medroxyprogesterone acetate?

Depo-Provera® Signup and view all the answers

Which medication is commonly used in women for the treatment of endometriosis, uterine fibroids, POCS, and hirsutism?

Goserelin Signup and view all the answers

What are the side effects commonly experienced by women using medications like leuprolide, goserelin, and nafarelin?

Hot flashes/sweats and depression Signup and view all the answers

Which medication is contraindicated in pregnancy and breastfeeding?

Goserelin Signup and view all the answers

What is the main use of GnRH antagonists like Cetrorelix and Ganirelix?

Assisted reproduction to suppress FSH/LH release Signup and view all the answers

What is the purpose of using GnRH antagonists in fertility treatment?

Prevent LH surge to avoid premature ovulation Signup and view all the answers

Which medication is approved for the treatment of advanced prostate cancer?

Degarelix Signup and view all the answers

What is the primary side effect associated with GnRH antagonists when used in fertility treatments?

Abdominal pain Signup and view all the answers

What is the main reason GnRH antagonists are used in vitro fertilization?

To prevent LH surge for laproscopic harvest of ova Signup and view all the answers

What is the common side effect associated with Drospirenone use in women?

Headache and nausea Signup and view all the answers

Which medication suppresses endogenous FSH/LH release to give exogenous FSH followed by midcycle LH for fertilization?

Bromocriptine mesylate Signup and view all the answers

Hormone Replacement Therapy and Breast Cancer Risk Quiz

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Questions and Answers

What is the structural analogue of spironolactone?

Which of the following is a C-19 progestin with anti-androgenic activity?

What is the main mechanism of action of Clomiphene citrate?

Which C-19 progestin has minimal or no overall androgenic side effects?

How do hormonal contraceptives like birth control pills affect FSH and LH release from the pituitary?

What is the main reason why estrogen is used alone should be given in a cyclic administration?

In what condition should estrogen therapy be used in combination with progesterone?

Which hormone replacement therapy is increasingly discouraged in postmenopausal women due to increased risks of breast cancer and cardiovascular events?

What is the primary function of continual administration of combination estrogen/progestin oral contraceptives for acne?

Which condition does estrogen primarily target by inhibiting bone resorption but not stimulating new bone synthesis?

What is the mechanism of action of drugs that block the production of ovarian-stimulating hormones?

Which drug can relieve endometriosis signs and symptoms by halting menstrual periods and the growth of endometrial implants?

Which type of C-19 progestins has anti-androgenic activity?

What is the concern related to the duration of therapy limitation for GnRH agonists in treating pelvic pain caused by endometriosis?

Which contraceptive method can help inhibit endometrial tissue growth by causing initial decidualization and then atrophy?

How do combination oral contraceptives help reduce dermatological manifestations in women with PCOS?

Which enzyme is more commonly known as 'Aromatase'?

What is one of the overall goals of therapy for women with PCOS?

How do high and low GnRH pulse frequencies affect LH and FSH release, respectively?

Which medication is commonly used for ovulation induction in women pursuing pregnancy?

Which class of enzymes is important in the growth and implantation of ectopic endometrium?

Which medication acts as an antagonist at estrogen receptors in the breast but a partial agonist at estrogen receptors in the endometrium and bone?

Which drug is primarily used for the treatment of breast cancers that are estrogen receptor-positive?

Which medication is a structural analogue of spironolactone?

Which type of progestins have minimal or no overall androgenic side effects?

Which contraceptive method involves inserting a T-shaped piece of plastic that releases the progestin levonorgestrel?

Which contraceptive method contains ethinyl estradiol and norelgestromin in a patch form?

Which contraceptive method involves capsules of etonorgestrel placed under the skin for slow release up to 3 years?

Which contraceptive method is reusable for one year and consists of segesterone and ethinyl estradiol?

Which contraceptive method is administered as an injection every 3 months and contains medroxyprogesterone acetate?

Which medication is commonly used in women for the treatment of endometriosis, uterine fibroids, POCS, and hirsutism?

What are the side effects commonly experienced by women using medications like leuprolide, goserelin, and nafarelin?

Which medication is contraindicated in pregnancy and breastfeeding?

What is the main use of GnRH antagonists like Cetrorelix and Ganirelix?

What is the purpose of using GnRH antagonists in fertility treatment?

Which medication is approved for the treatment of advanced prostate cancer?

What is the primary side effect associated with GnRH antagonists when used in fertility treatments?

What is the main reason GnRH antagonists are used in vitro fertilization?

What is the common side effect associated with Drospirenone use in women?

Which medication suppresses endogenous FSH/LH release to give exogenous FSH followed by midcycle LH for fertilization?

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