Esophagus and Swallowing Quiz

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Questions and Answers

What is the primary function of the lower esophageal sphincter (LES)?

  • To regulate the secretion of digestive enzymes
  • To aid in the ingestion of food
  • To facilitate the propulsion of bolus
  • To provide a pressure barrier between the esophagus and stomach (correct)

Secondary peristalsis is more common than previously thought.

False (B)

What may occur following a cerebrovascular accident regarding swallowing?

Coordinated outflow of swallowing may be altered.

The maximum weight that can be overcome when attempting to swallow a bolus attached by a string is ______.

<p>5 to 10 g</p> Signup and view all the answers

Match the following terms with their definitions:

<p>Secondary peristalsis = Not as common as once thought Cricopharyngeus = Striated muscle in the esophagus Cerebrovascular accident = May disrupt coordinated outflow LES = Acts as a valve between esophagus and stomach</p> Signup and view all the answers

What does the retrocricoid portion of the inferior constrictor serve as?

<p>The upper sphincter of the esophagus (A)</p> Signup and view all the answers

The cervical portion of the esophagus is shorter than the thoracic portion.

<p>True (A)</p> Signup and view all the answers

Which nerve plexus lies on the muscular wall of the esophagus?

<p>Esophageal nerve plexus</p> Signup and view all the answers

The thoracic duct passes through the diaphragm on the anterior surface of the _____ column.

<p>vertebral</p> Signup and view all the answers

Match the following parts of the esophagus with their functions:

<p>Retrothyroid portion = Contracts to force the bolus into the esophagus Thoracic duct = Lymphatic drainage Cricopharyngeus = Part of the inferior constrictor muscle Vagal nerves = Control involuntary functions of the esophagus</p> Signup and view all the answers

At which thoracic vertebra does the esophagus begin to move vertically away from the spine?

<p>8th thoracic vertebra (A)</p> Signup and view all the answers

The descending thoracic aorta is located on the right side of the esophagus.

<p>False (B)</p> Signup and view all the answers

Who showed that the retrocricoid and retrothyroid portions of the inferior constrictor serve different functions?

<p>Keith</p> Signup and view all the answers

What happens to the abdominal pressure in the upright position compared to atmospheric pressure?

<p>It is negative (A)</p> Signup and view all the answers

In the supine position, the gastroesophageal pressure gradient increases, preventing reflux into the esophagus.

<p>False (B)</p> Signup and view all the answers

What maintains the intrinsic myogenic tone of the lower esophageal sphincter (LES)?

<p>Neural and hormonal mechanisms</p> Signup and view all the answers

The hormones _____ and _____ have been shown to increase LES pressure.

<p>gastrin, motilin</p> Signup and view all the answers

Which neurotransmitters are involved in regulating LES pressure?

<p>α-Adrenergic and β-blockers (D)</p> Signup and view all the answers

Match the factors with their roles in relation to the lower esophageal sphincter (LES):

<p>Gastrin = Increases LES pressure Cholecystokinin = Decreases LES pressure Vagus nerve = Carries both excitatory and inhibitory fibers α-blockers = Decrease LES pressure</p> Signup and view all the answers

Relaxation of the LES coincides with peristaltic waves in the esophagus.

<p>True (A)</p> Signup and view all the answers

What is a potential cause of gastroesophageal reflux disease (GERD)?

<p>Spontaneous lower esophageal relaxation</p> Signup and view all the answers

How long does the whole course of rise and fall of occlusive pressure occupy in the esophagus?

<p>3 to 5 seconds (B)</p> Signup and view all the answers

The peak of a primary peristaltic contraction reaches the distal esophagus approximately 5 seconds after swallowing starts.

<p>False (B)</p> Signup and view all the answers

What is the speed range at which the primary peristaltic wave moves down the esophagus?

<p>2 to 4 cm/s</p> Signup and view all the answers

The peak of a peristaltic contraction lasts about ______ seconds.

<p>0.5</p> Signup and view all the answers

What happens when the act of swallowing is rapidly repeated?

<p>The esophagus remains relaxed (B)</p> Signup and view all the answers

Efficient contraction of the esophagus is solely governed by gravity.

<p>False (B)</p> Signup and view all the answers

What is the resting level of intraluminal esophageal pressure mentioned in the text?

<p>30 mmHg</p> Signup and view all the answers

What is more common during wakefulness and the upright position in healthy individuals?

<p>Physiologic gastroesophageal reflux (B)</p> Signup and view all the answers

Normal subjects can rapidly clear gastric juice from the esophagus regardless of their position.

<p>True (A)</p> Signup and view all the answers

What is the primary reason for increased reflux episodes in healthy individuals when they are upright?

<p>Transient losses of the gastroesophageal barrier</p> Signup and view all the answers

Gastroesophageal reflux is typically observed when the lower esophageal sphincter (LES) _____ or when intra-gastric pressure overcomes sphincter pressure.

<p>relaxes</p> Signup and view all the answers

Match the terms with their descriptions:

<p>LES = Lower esophageal sphincter Intra-gastric pressure = Pressure within the stomach Gastroesophageal reflux = Backward flow of gastric contents into the esophagus Healthy individuals = People with normal physiological functions</p> Signup and view all the answers

Which of the following statements is accurate regarding esophageal reflux mechanisms?

<p>Reflux happens mainly during transient losses of the gastroesophageal barrier. (B)</p> Signup and view all the answers

Physiological reflux occurs more frequently during sleep than when awake.

<p>False (B)</p> Signup and view all the answers

What is the role of the cricopharyngeus in relation to the pharyngeal muscles?

<p>To relax</p> Signup and view all the answers

What condition is characterized by the lining of the esophagus being made up of columnar epithelium instead of normal squamous epithelium?

<p>Barrett’s esophagus (A)</p> Signup and view all the answers

Gastroesophageal reflux is always associated with visible mucosal abnormalities.

<p>False (B)</p> Signup and view all the answers

What diagnostic technique is used to observe coordinated esophageal peristalsis?

<p>Barium swallow</p> Signup and view all the answers

A small hiatal hernia is usually not associated with ______________.

<p>gastroesophageal reflux symptoms</p> Signup and view all the answers

What is the appearance of Barrett’s esophagus when viewed during an endoscopy?

<p>Redder, salmon-colored mucosa (A)</p> Signup and view all the answers

Histologically, Barrett’s esophagus appears as intestinal metaplasia.

<p>True (A)</p> Signup and view all the answers

What is essential for confirming the presence of Barrett's esophagus?

<p>Biopsy</p> Signup and view all the answers

Match the esophageal conditions with their descriptions:

<p>Barrett’s esophagus = Lining replaced by columnar epithelium Hiatal hernia = Displacement of esophagogastric junction Gastroesophageal reflux = Reflux that may not show mucosal abnormalities Esophageal strictures = Narrowing of the esophagus</p> Signup and view all the answers

Flashcards

Esophageal Peristalsis

The coordinated muscular contractions that move food through the esophagus.

LES Pressure

The pressure exerted by the lower esophageal sphincter (LES) to keep the stomach contents from refluxing back into the esophagus.

Swallowing Center

The rhythmic, coordinated activation of esophageal muscles, triggered by swallowing, ensuring efficient food transport.

Lower Esophageal Sphincter (LES)

The point where the esophagus connects to the stomach, acting as a barrier and pressure-sensitive valve.

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Hiatal Hernia

A condition where the stomach protrudes through the diaphragm, weakening the lower esophageal sphincter and potentially causing reflux.

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Occlusive Pressure

The pressure inside the esophagus when food moves down, it rises to a peak for half a second, then drops over 1.5 seconds.

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Peristalsis

A continuous wave of muscular contractions that pushes food down the esophagus.

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Primary Peristalsis

The initial peristaltic wave that starts after swallowing.

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Speed of Peristaltic Wave

The speed of the peristaltic wave moving down the esophagus is about 2 to 4 centimeters per second.

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Time to Reach Distal Esophagus

The time it takes for the primary peristaltic wave to reach the end of the esophagus after swallowing is about 9 seconds.

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Swallowing Center Activation

The act of swallowing initiates signals from the swallowing center to muscles in the esophagus, causing the peristaltic wave.

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Rapid Swallow Relaxation

Rapidly repeating swallows don't immediately trigger peristalsis. The esophagus remains relaxed, waiting for the last swallow before initiating the wave.

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Sequential Muscle Activation

Muscle activation is sequential, meaning one part of the esophagus contracts before the next, creating the wave of pressure.

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What muscle coordinates with the cricopharyngeus?

The muscle that helps the cricopharyngeus relax during swallowing. This relaxation allows food to pass from the pharynx into the esophagus.

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What is the gastro-esophageal muscular ring?

A ring of muscle at the junction of the esophagus and stomach that helps prevent reflux.

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What is physiologic reflux?

The natural process of stomach contents flowing back up into the esophagus.

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How do normal subjects handle physiologic reflux?

The ability to clear acid from the esophagus quickly and effectively.

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Why is physiologic reflux more common when awake and upright?

Physiologic reflux is more common when awake and upright due to changes in pressure and LES relaxation.

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How do transient losses of the gastroesophageal barrier cause reflux?

Transient losses of the gastroesophageal barrier can lead to reflux. This occurs when either the LES relaxes or pressure in the stomach overcomes the sphincter.

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What is the role of the LES in reflux?

The lower esophageal sphincter (LES) is a muscle that helps prevent reflux. It relaxes temporarily, allowing food to pass into the stomach, but normally remains contracted.

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How does gastric pressure contribute to reflux?

Pressure inside the stomach can overcome the LES, pushing acid back up into the esophagus. This is another mechanism for reflux.

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Pressure difference in upright position

The pressure inside the stomach is lower than the pressure outside the body, which helps keep gastric contents inside.

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Reflux in upright position

This pressure difference makes it easier for stomach acid to flow back up into the esophagus.

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Pressure difference in supine position

The pressure inside the stomach is higher than the pressure outside the body, which helps prevent reflux.

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Intrinsic myogenic tone of LES

The lower esophageal sphincter (LES) naturally stays closed, preventing stomach contents from flowing into the esophagus.

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Neural and hormonal modulation of LES

Nerves and hormones can adjust the LES pressure.

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Effect of chemicals on LES pressure

Certain chemicals can either increase or decrease the pressure of the lower esophageal sphincter.

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Unguarded LES relaxation

Failure of the LES to relax at the right time allows reflux to occur.

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Spontaneous lower esophageal relaxation

The LES doesn't always relax properly to allow food to pass through, leading to reflux.

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Cricopharyngeal Muscle

The upper esophageal sphincter, located at the junction of the pharynx and esophagus, is responsible for preventing air from entering the esophagus during breathing and food from backing up into the pharynx during swallowing.

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Cricopharyngeal Muscle Function

The cricopharyngeal muscle has two separate functions: the retrothyroid portion contracts to push food down, while the retrocricoid portion relaxes, allowing food to pass into the esophagus.

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Cervical Esophagus

The cervical part of the esophagus lies in the neck, extending from the pharynx to the thorax.

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Thoracic Esophagus

The thoracic part of the esophagus runs through the chest cavity, passing through the diaphragm (the muscle that separates the chest from the abdomen) before connecting to the stomach.

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Thoracic Duct

The thoracic duct is a large lymphatic vessel that collects lymph fluid from the lower body and drains it back into the circulatory system. It passes through the diaphragm alongside the esophagus.

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Esophagus and Vertebral Column

The esophagus is in close contact with the vertebral bodies (bones of the spine) as it travels through the chest. This proximity helps shape its path.

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Azygos Vein

The azygos vein is a large vein that collects blood from the chest and abdomen and drains it into the superior vena cava. It lies on the right side of the esophagus in the chest.

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Descending Thoracic Aorta

The descending thoracic aorta is a major artery that carries oxygenated blood from the heart down to the lower body. It lies on the left side of the esophagus in the chest.

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Barrett's Esophagus (BE)

A condition where the lining of the lower esophagus changes from squamous epithelium to columnar epithelium, often due to long-term exposure to stomach acid.

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Intestinal Metaplasia (IM)

A change in the type of cells lining an organ, specifically in Barrett's Esophagus, where the normal squamous epithelium is replaced by columnar epithelium.

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Endoscopy

A diagnostic test used to visualize the esophagus and stomach using a flexible tube with a camera attached.

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Biopsy

A procedure where a small sample of tissue is taken for examination under a microscope, often to diagnose conditions like Barrett's Esophagus.

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Esophagogastric Junction

The junction between the esophagus and the stomach, often affected in cases of gastroesophageal reflux disease.

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Barium Swallow (Esophagram)

A test where barium is swallowed to visualize the esophagus and stomach on x-ray, helping to detect abnormalities.

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Gastroesophageal Reflux (GER)

A condition where gastric contents flow back up into the esophagus, often causing heartburn.

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Study Notes

Surgical Anatomy

  • The esophagus is a muscular tube, beginning as a continuation of the pharynx and ending at the cardia of the stomach
  • During swallowing, the esophagus's proximal points of fixation move craniad.
  • The esophagus generally stays in the midline, but has a slight deviation to the left in the neck and upper thorax, returning to the midline in the mid-thorax near the trachea's bifurcation.
  • In the lower thorax, the esophagus deviates to the left and anterior to pass through the diaphragmatic hiatus.

Physiology

  • Alimentation requires transporting food and drink from the mouth to the stomach.
  • The esophagus and pharynx are divided into 3 parts: mouth/hypopharynx, and esophagus.
  • Swallowing involves the tongue and pharynx acting as piston pumps, the esophagus and cardia acting as worm-drive pumps, and 3 pharyngeal valves(soft palate, epiglottis, and cricopharyngeus) and one esophageal valve (lower esophageal sphincter): LES).
  • Swallowing is a reflex action initiating with the tongue pushing a bolus into the pharynx, which closes off the nasopharynx using the soft palate.
  • The hyoid bone moves upward and forward as the larynx and epiglottis are elevated, protecting the larynx from aspiration.

Tests to Detect Functional Abnormalities

  • Endoscopic evaluation is the initial diagnostic procedure to test the esophagus for disease.
  • Los Angeles grading system is used to categorize and quantify esophagitis.
  • Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disease requiring treatment.
  • Barrett's esophagus is the transformation of distal esophageal epithelium from squamous to specialized columnar epithelium.
  • Radiographic analysis is used for evaluating anatomy and motility.
  • High-resolution manometry provides detailed evaluation of esophageal motor function using pressure-sensitive transducers positioned along the esophageal canal.
  • Esophageal impedance recordings give information about esophageal function and gastroesophageal reflux.
  • Esophageal transit scintigraphy records the transit of a water-based or nonacidic bolus through the esophagus.
  • Video- and cineradiography used for evaluating the pharyngeal phase of swallowing.

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