Podcast
Questions and Answers
What is the primary function of the lower esophageal sphincter (LES)?
What is the primary function of the lower esophageal sphincter (LES)?
- To regulate the secretion of digestive enzymes
- To aid in the ingestion of food
- To facilitate the propulsion of bolus
- To provide a pressure barrier between the esophagus and stomach (correct)
Secondary peristalsis is more common than previously thought.
Secondary peristalsis is more common than previously thought.
False (B)
What may occur following a cerebrovascular accident regarding swallowing?
What may occur following a cerebrovascular accident regarding swallowing?
Coordinated outflow of swallowing may be altered.
The maximum weight that can be overcome when attempting to swallow a bolus attached by a string is ______.
The maximum weight that can be overcome when attempting to swallow a bolus attached by a string is ______.
Match the following terms with their definitions:
Match the following terms with their definitions:
What does the retrocricoid portion of the inferior constrictor serve as?
What does the retrocricoid portion of the inferior constrictor serve as?
The cervical portion of the esophagus is shorter than the thoracic portion.
The cervical portion of the esophagus is shorter than the thoracic portion.
Which nerve plexus lies on the muscular wall of the esophagus?
Which nerve plexus lies on the muscular wall of the esophagus?
The thoracic duct passes through the diaphragm on the anterior surface of the _____ column.
The thoracic duct passes through the diaphragm on the anterior surface of the _____ column.
Match the following parts of the esophagus with their functions:
Match the following parts of the esophagus with their functions:
At which thoracic vertebra does the esophagus begin to move vertically away from the spine?
At which thoracic vertebra does the esophagus begin to move vertically away from the spine?
The descending thoracic aorta is located on the right side of the esophagus.
The descending thoracic aorta is located on the right side of the esophagus.
Who showed that the retrocricoid and retrothyroid portions of the inferior constrictor serve different functions?
Who showed that the retrocricoid and retrothyroid portions of the inferior constrictor serve different functions?
What happens to the abdominal pressure in the upright position compared to atmospheric pressure?
What happens to the abdominal pressure in the upright position compared to atmospheric pressure?
In the supine position, the gastroesophageal pressure gradient increases, preventing reflux into the esophagus.
In the supine position, the gastroesophageal pressure gradient increases, preventing reflux into the esophagus.
What maintains the intrinsic myogenic tone of the lower esophageal sphincter (LES)?
What maintains the intrinsic myogenic tone of the lower esophageal sphincter (LES)?
The hormones _____ and _____ have been shown to increase LES pressure.
The hormones _____ and _____ have been shown to increase LES pressure.
Which neurotransmitters are involved in regulating LES pressure?
Which neurotransmitters are involved in regulating LES pressure?
Match the factors with their roles in relation to the lower esophageal sphincter (LES):
Match the factors with their roles in relation to the lower esophageal sphincter (LES):
Relaxation of the LES coincides with peristaltic waves in the esophagus.
Relaxation of the LES coincides with peristaltic waves in the esophagus.
What is a potential cause of gastroesophageal reflux disease (GERD)?
What is a potential cause of gastroesophageal reflux disease (GERD)?
How long does the whole course of rise and fall of occlusive pressure occupy in the esophagus?
How long does the whole course of rise and fall of occlusive pressure occupy in the esophagus?
The peak of a primary peristaltic contraction reaches the distal esophagus approximately 5 seconds after swallowing starts.
The peak of a primary peristaltic contraction reaches the distal esophagus approximately 5 seconds after swallowing starts.
What is the speed range at which the primary peristaltic wave moves down the esophagus?
What is the speed range at which the primary peristaltic wave moves down the esophagus?
The peak of a peristaltic contraction lasts about ______ seconds.
The peak of a peristaltic contraction lasts about ______ seconds.
What happens when the act of swallowing is rapidly repeated?
What happens when the act of swallowing is rapidly repeated?
Efficient contraction of the esophagus is solely governed by gravity.
Efficient contraction of the esophagus is solely governed by gravity.
What is the resting level of intraluminal esophageal pressure mentioned in the text?
What is the resting level of intraluminal esophageal pressure mentioned in the text?
What is more common during wakefulness and the upright position in healthy individuals?
What is more common during wakefulness and the upright position in healthy individuals?
Normal subjects can rapidly clear gastric juice from the esophagus regardless of their position.
Normal subjects can rapidly clear gastric juice from the esophagus regardless of their position.
What is the primary reason for increased reflux episodes in healthy individuals when they are upright?
What is the primary reason for increased reflux episodes in healthy individuals when they are upright?
Gastroesophageal reflux is typically observed when the lower esophageal sphincter (LES) _____ or when intra-gastric pressure overcomes sphincter pressure.
Gastroesophageal reflux is typically observed when the lower esophageal sphincter (LES) _____ or when intra-gastric pressure overcomes sphincter pressure.
Match the terms with their descriptions:
Match the terms with their descriptions:
Which of the following statements is accurate regarding esophageal reflux mechanisms?
Which of the following statements is accurate regarding esophageal reflux mechanisms?
Physiological reflux occurs more frequently during sleep than when awake.
Physiological reflux occurs more frequently during sleep than when awake.
What is the role of the cricopharyngeus in relation to the pharyngeal muscles?
What is the role of the cricopharyngeus in relation to the pharyngeal muscles?
What condition is characterized by the lining of the esophagus being made up of columnar epithelium instead of normal squamous epithelium?
What condition is characterized by the lining of the esophagus being made up of columnar epithelium instead of normal squamous epithelium?
Gastroesophageal reflux is always associated with visible mucosal abnormalities.
Gastroesophageal reflux is always associated with visible mucosal abnormalities.
What diagnostic technique is used to observe coordinated esophageal peristalsis?
What diagnostic technique is used to observe coordinated esophageal peristalsis?
A small hiatal hernia is usually not associated with ______________.
A small hiatal hernia is usually not associated with ______________.
What is the appearance of Barrett’s esophagus when viewed during an endoscopy?
What is the appearance of Barrett’s esophagus when viewed during an endoscopy?
Histologically, Barrett’s esophagus appears as intestinal metaplasia.
Histologically, Barrett’s esophagus appears as intestinal metaplasia.
What is essential for confirming the presence of Barrett's esophagus?
What is essential for confirming the presence of Barrett's esophagus?
Match the esophageal conditions with their descriptions:
Match the esophageal conditions with their descriptions:
Flashcards
Esophageal Peristalsis
Esophageal Peristalsis
The coordinated muscular contractions that move food through the esophagus.
LES Pressure
LES Pressure
The pressure exerted by the lower esophageal sphincter (LES) to keep the stomach contents from refluxing back into the esophagus.
Swallowing Center
Swallowing Center
The rhythmic, coordinated activation of esophageal muscles, triggered by swallowing, ensuring efficient food transport.
Lower Esophageal Sphincter (LES)
Lower Esophageal Sphincter (LES)
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Hiatal Hernia
Hiatal Hernia
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Occlusive Pressure
Occlusive Pressure
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Peristalsis
Peristalsis
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Primary Peristalsis
Primary Peristalsis
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Speed of Peristaltic Wave
Speed of Peristaltic Wave
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Time to Reach Distal Esophagus
Time to Reach Distal Esophagus
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Swallowing Center Activation
Swallowing Center Activation
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Rapid Swallow Relaxation
Rapid Swallow Relaxation
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Sequential Muscle Activation
Sequential Muscle Activation
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What muscle coordinates with the cricopharyngeus?
What muscle coordinates with the cricopharyngeus?
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What is the gastro-esophageal muscular ring?
What is the gastro-esophageal muscular ring?
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What is physiologic reflux?
What is physiologic reflux?
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How do normal subjects handle physiologic reflux?
How do normal subjects handle physiologic reflux?
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Why is physiologic reflux more common when awake and upright?
Why is physiologic reflux more common when awake and upright?
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How do transient losses of the gastroesophageal barrier cause reflux?
How do transient losses of the gastroesophageal barrier cause reflux?
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What is the role of the LES in reflux?
What is the role of the LES in reflux?
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How does gastric pressure contribute to reflux?
How does gastric pressure contribute to reflux?
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Pressure difference in upright position
Pressure difference in upright position
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Reflux in upright position
Reflux in upright position
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Pressure difference in supine position
Pressure difference in supine position
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Intrinsic myogenic tone of LES
Intrinsic myogenic tone of LES
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Neural and hormonal modulation of LES
Neural and hormonal modulation of LES
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Effect of chemicals on LES pressure
Effect of chemicals on LES pressure
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Unguarded LES relaxation
Unguarded LES relaxation
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Spontaneous lower esophageal relaxation
Spontaneous lower esophageal relaxation
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Cricopharyngeal Muscle
Cricopharyngeal Muscle
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Cricopharyngeal Muscle Function
Cricopharyngeal Muscle Function
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Cervical Esophagus
Cervical Esophagus
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Thoracic Esophagus
Thoracic Esophagus
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Thoracic Duct
Thoracic Duct
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Esophagus and Vertebral Column
Esophagus and Vertebral Column
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Azygos Vein
Azygos Vein
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Descending Thoracic Aorta
Descending Thoracic Aorta
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Barrett's Esophagus (BE)
Barrett's Esophagus (BE)
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Intestinal Metaplasia (IM)
Intestinal Metaplasia (IM)
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Endoscopy
Endoscopy
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Biopsy
Biopsy
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Esophagogastric Junction
Esophagogastric Junction
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Barium Swallow (Esophagram)
Barium Swallow (Esophagram)
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Gastroesophageal Reflux (GER)
Gastroesophageal Reflux (GER)
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Study Notes
Surgical Anatomy
- The esophagus is a muscular tube, beginning as a continuation of the pharynx and ending at the cardia of the stomach
- During swallowing, the esophagus's proximal points of fixation move craniad.
- The esophagus generally stays in the midline, but has a slight deviation to the left in the neck and upper thorax, returning to the midline in the mid-thorax near the trachea's bifurcation.
- In the lower thorax, the esophagus deviates to the left and anterior to pass through the diaphragmatic hiatus.
Physiology
- Alimentation requires transporting food and drink from the mouth to the stomach.
- The esophagus and pharynx are divided into 3 parts: mouth/hypopharynx, and esophagus.
- Swallowing involves the tongue and pharynx acting as piston pumps, the esophagus and cardia acting as worm-drive pumps, and 3 pharyngeal valves(soft palate, epiglottis, and cricopharyngeus) and one esophageal valve (lower esophageal sphincter): LES).
- Swallowing is a reflex action initiating with the tongue pushing a bolus into the pharynx, which closes off the nasopharynx using the soft palate.
- The hyoid bone moves upward and forward as the larynx and epiglottis are elevated, protecting the larynx from aspiration.
Tests to Detect Functional Abnormalities
- Endoscopic evaluation is the initial diagnostic procedure to test the esophagus for disease.
- Los Angeles grading system is used to categorize and quantify esophagitis.
- Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disease requiring treatment.
- Barrett's esophagus is the transformation of distal esophageal epithelium from squamous to specialized columnar epithelium.
- Radiographic analysis is used for evaluating anatomy and motility.
- High-resolution manometry provides detailed evaluation of esophageal motor function using pressure-sensitive transducers positioned along the esophageal canal.
- Esophageal impedance recordings give information about esophageal function and gastroesophageal reflux.
- Esophageal transit scintigraphy records the transit of a water-based or nonacidic bolus through the esophagus.
- Video- and cineradiography used for evaluating the pharyngeal phase of swallowing.
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