Esophageal Achalasia Symptoms and Causes
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Questions and Answers

What is the primary symptom of achalasia?

  • Difficulty swallowing solids and liquids (correct)
  • Weight loss
  • Heartburn
  • Chest pain or discomfort
  • What is the believed cause of achalasia in most cases?

  • Unknown, but related to nerve damage or abnormalities (correct)
  • Genetic disorders
  • Infection with certain viruses or bacteria
  • Autoimmune diseases
  • Which treatment option is used to relax the lower esophageal sphincter?

  • Nitrates or calcium channel blockers (correct)
  • Botox injections
  • Laparoscopic Heller myotomy
  • Pneumatic dilation
  • What is the purpose of an esophagogram in diagnosing achalasia?

    <p>To examine the swallowing process using X-ray</p> Signup and view all the answers

    What is characterized by absent or incomplete primary peristalsis?

    <p>Achalasia</p> Signup and view all the answers

    What is the result of incomplete relaxation of the lower esophageal sphincter in achalasia?

    <p>Elevated LES pressure</p> Signup and view all the answers

    Which diagnostic test is used to assess the movement of food through the esophagus?

    <p>Timed barium esophagogram</p> Signup and view all the answers

    What is the purpose of laparoscopic Heller myotomy in treating achalasia?

    <p>To cut the muscle of the lower esophageal sphincter</p> Signup and view all the answers

    What is the result of abnormal esophageal contractions in achalasia?

    <p>Regurgitation of food</p> Signup and view all the answers

    What is the recommended lifestyle change to help manage achalasia?

    <p>Eating smaller, more frequent meals</p> Signup and view all the answers

    Study Notes

    Symptoms

    • Difficulty swallowing (dysphagia) solids and liquids
    • Regurgitation of food
    • Chest pain or discomfort
    • Coughing or choking on food
    • Weight loss
    • Heartburn
    • Difficulty burping or vomiting

    Causes

    • Unknown in most cases, but believed to be related to:
      • Damage to the nerves that control the esophagus
      • Abnormality in the nerve cells that control the lower esophageal sphincter (LES)
      • Inflammation or scarring of the esophagus
      • Certain genetic disorders or autoimmune diseases
      • Infection with certain viruses or bacteria

    Treatment Options

    • Medical Therapy:
      • Nitrates or calcium channel blockers to relax the LES
      • Botox injections to temporarily relax the LES
    • Endoscopic Therapy:
      • Pneumatic dilation to stretch the LES
      • Botulinum toxin injection to relax the LES
    • Surgical Therapy:
      • Laparoscopic Heller myotomy to cut the muscle of the LES
      • Peroral endoscopic myotomy (POEM) to cut the muscle of the LES through the mouth
    • Lifestyle Changes:
      • Eating smaller, more frequent meals
      • Avoiding heavy or rich foods
      • Raising the head of the bed 6-8 inches

    Diagnosis

    • Endoscopy: to visualize the esophagus and rule out other conditions
    • Esophagogram: to examine the swallowing process using X-ray
    • Manometry: to measure the muscle contractions of the esophagus
    • Timed barium esophagogram: to assess the movement of food through the esophagus

    Esophageal Motility

    • Primary peristalsis: the normal wave-like muscle contraction of the esophagus
    • Secondary peristalsis: the contraction of the esophagus in response to food or liquid
    • Achalasia: characterized by:
      • Absent or incomplete primary peristalsis
      • Incomplete relaxation of the LES
      • Elevated LES pressure
      • Abnormal esophageal contractions

    Symptoms

    • Difficulty swallowing solids and liquids due to achalasia
    • Regurgitation of food, a common symptom of achalasia
    • Chest pain or discomfort associated with swallowing
    • Coughing or choking on food, a risk of achalasia
    • Weight loss due to difficulty swallowing and eating
    • Heartburn, a symptom of achalasia
    • Difficulty burping or vomiting, a characteristic of achalasia

    Causes

    • Unknown causes in most cases
    • Damage to nerves controlling the esophagus, a possible cause
    • Abnormality in nerve cells controlling the lower esophageal sphincter (LES)
    • Inflammation or scarring of the esophagus, a possible cause
    • Genetic disorders or autoimmune diseases, a possible cause
    • Infection with certain viruses or bacteria, a possible cause

    Treatment Options

    Medical Therapy

    • Nitrates or calcium channel blockers to relax the LES
    • Botox injections to temporarily relax the LES

    Endoscopic Therapy

    • Pneumatic dilation to stretch the LES
    • Botulinum toxin injection to relax the LES

    Surgical Therapy

    • Laparoscopic Heller myotomy to cut the muscle of the LES
    • Peroral endoscopic myotomy (POEM) to cut the muscle of the LES through the mouth

    Lifestyle Changes

    • Eating smaller, more frequent meals to manage symptoms
    • Avoiding heavy or rich foods to manage symptoms
    • Raising the head of the bed 6-8 inches to reduce symptoms

    Diagnosis

    • Endoscopy to visualize the esophagus and rule out other conditions
    • Esophagogram to examine the swallowing process using X-ray
    • Manometry to measure the muscle contractions of the esophagus
    • Timed barium esophagogram to assess the movement of food through the esophagus

    Esophageal Motility

    Normal Motility

    • Primary peristalsis: the normal wave-like muscle contraction of the esophagus
    • Secondary peristalsis: the contraction of the esophagus in response to food or liquid

    Achalasia

    • Characterized by absent or incomplete primary peristalsis
    • Incomplete relaxation of the LES
    • Elevated LES pressure
    • Abnormal esophageal contractions

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    Description

    This quiz covers the symptoms and causes of esophageal achalasia, a disorder that affects the esophagus and can cause difficulty swallowing, chest pain, and other symptoms.

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