Esmolol Overview and Guidelines
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Questions and Answers

What is the classification of Esmolol?

  • Class 2 antiarrhythmic (correct)
  • Calcium channel blocker
  • Beta adrenergic antagonist (correct)
  • Alpha adrenergic agonist

What action does Esmolol perform on the heart?

Inhibits the strength of the heart's contractions and heart rate, resulting in a decrease in cardiac oxygen consumption.

Which of the following are indications for Esmolol? (Select all that apply)

  • Supraventricular tachyarrhythmia's (correct)
  • Chronic obstructive pulmonary disease
  • Acute coronary syndrome (correct)
  • Acute Bronchospasm

Which of the following are contraindications for Esmolol? (Select all that apply)

<p>Bradycardia (B), Sick sinus syndrome (C), Pulmonary edema (D)</p> Signup and view all the answers

What are some adverse effects of Esmolol? (Select all that apply)

<p>Nausea/Vomiting (A), Injection site reaction (B), Hypotension (D)</p> Signup and view all the answers

What is the adult dosage for Esmolol?

<p>500 mcg/kg (0.5 mg/kg) IV/IO over 1 min, followed by a 50 mcg/kg/min infusion over 4 min (max total 200 mcg/kg).</p> Signup and view all the answers

What is the pediatric dosage for Esmolol?

<p>500 mcg/kg IV/IO over 1 min followed by an infusion at 25 to 200 mcg/kg/min.</p> Signup and view all the answers

Esmolol has a half life of ______ minutes.

<p>5 to 9</p> Signup and view all the answers

Esmolol has a pregnancy classification of C.

<p>True (A)</p> Signup and view all the answers

Study Notes

Esmolol Overview

  • Classification: Beta adrenergic antagonist, Class 2 antiarrhythmic
  • Used to inhibit heart contractions and reduce heart rate, minimizing cardiac oxygen consumption

Indications for Use

  • Treats acute coronary syndrome (ACS)
  • Management of myocardial infarction (MI)
  • Addresses acute hypertension
  • Controls supraventricular tachyarrhythmias
  • Useful in cases of thyrotoxicosis

Contraindications

  • Not recommended for patients with acute bronchospasm or COPD
  • Avoid in individuals with 2nd or 3rd-degree heart block
  • Contraindicated in bradycardia, cardiogenic shock, and pulmonary edema
  • Caution in those with sick sinus syndrome or known sensitivity to the drug

Adverse Effects

  • Possible side effects include hypotension and sinus bradycardia
  • May cause AV block and cardiac arrest
  • Other side effects: nausea, vomiting, and hypoglycemia
  • Injection site reactions can occur

Dosage Guidelines

  • Adult Dosage: Initial bolus of 500 mcg/kg IV/IO over 1 minute, followed by a continuous infusion of 50 mcg/kg/min
  • If inadequate response, a second bolus of 500 mcg/kg may be administered and the infusion rate can be increased to 100 mcg/kg/min (maximum 300 mcg/kg/min)
  • Pediatric Dosage: 500 mcg/kg IV/IO over 1 minute, followed by an infusion of 25 to 200 mcg/kg/min

Special Considerations

  • Esmolol has a short half-life of 5 to 9 minutes
  • Adverse effects are typically transient due to this short half-life
  • Effects generally resolve within 10 to 20 minutes

Pregnancy Classification

  • Classified as Category C, indicating potential risks not ruled out during pregnancy

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Description

This quiz provides a comprehensive overview of Esmolol, including its classification, indications for use, and contraindications. It also covers adverse effects and dosage guidelines necessary for clinical practice. Test your knowledge on this important beta adrenergic antagonist used in various cardiac conditions.

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