Questions and Answers
What is the classification of Esmolol?
What action does Esmolol perform on the heart?
Inhibits the strength of the heart's contractions and heart rate, resulting in a decrease in cardiac oxygen consumption.
Which of the following are indications for Esmolol? (Select all that apply)
Which of the following are contraindications for Esmolol? (Select all that apply)
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What are some adverse effects of Esmolol? (Select all that apply)
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What is the adult dosage for Esmolol?
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What is the pediatric dosage for Esmolol?
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Esmolol has a half life of ______ minutes.
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Esmolol has a pregnancy classification of C.
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Study Notes
Esmolol Overview
- Classification: Beta adrenergic antagonist, Class 2 antiarrhythmic
- Used to inhibit heart contractions and reduce heart rate, minimizing cardiac oxygen consumption
Indications for Use
- Treats acute coronary syndrome (ACS)
- Management of myocardial infarction (MI)
- Addresses acute hypertension
- Controls supraventricular tachyarrhythmias
- Useful in cases of thyrotoxicosis
Contraindications
- Not recommended for patients with acute bronchospasm or COPD
- Avoid in individuals with 2nd or 3rd-degree heart block
- Contraindicated in bradycardia, cardiogenic shock, and pulmonary edema
- Caution in those with sick sinus syndrome or known sensitivity to the drug
Adverse Effects
- Possible side effects include hypotension and sinus bradycardia
- May cause AV block and cardiac arrest
- Other side effects: nausea, vomiting, and hypoglycemia
- Injection site reactions can occur
Dosage Guidelines
- Adult Dosage: Initial bolus of 500 mcg/kg IV/IO over 1 minute, followed by a continuous infusion of 50 mcg/kg/min
- If inadequate response, a second bolus of 500 mcg/kg may be administered and the infusion rate can be increased to 100 mcg/kg/min (maximum 300 mcg/kg/min)
- Pediatric Dosage: 500 mcg/kg IV/IO over 1 minute, followed by an infusion of 25 to 200 mcg/kg/min
Special Considerations
- Esmolol has a short half-life of 5 to 9 minutes
- Adverse effects are typically transient due to this short half-life
- Effects generally resolve within 10 to 20 minutes
Pregnancy Classification
- Classified as Category C, indicating potential risks not ruled out during pregnancy
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Description
This quiz provides a comprehensive overview of Esmolol, including its classification, indications for use, and contraindications. It also covers adverse effects and dosage guidelines necessary for clinical practice. Test your knowledge on this important beta adrenergic antagonist used in various cardiac conditions.
