29 Questions
What type of island is associated with the pathogenesis of EPEC?
Pathogenicity island
What is the function of BFP pili in some EPEC strains?
To adhere to gut epithelial cells
What is the main difference between EPEC and RPEC?
RPEC is a type of EPEC with an eae gene
What is the effect of EPEC on gut epithelial cells?
It triggers a cascade of intracellular reactions
What is the primary cause of diarrhea in suckling rabbits infected with RPEC?
Lesions in the small and large intestines
What is the mortality rate associated with EPEC in rabbits?
25-40%
What is the typical location of lesions in the intestine associated with E. coli?
Small intestine
What is the primary mechanism of action of Shiga toxins in humans?
Blocking protein synthesis by inhibiting ribosomal peptide elongation
What is the role of Shiga toxin in E. coli infections?
It inhibits protein synthesis in host cells
What is the primary source of E. coli O157:H7 in humans?
Contaminated food from bovines
What is the primary association of E. coli O139 and O141 strains?
They are usually hemolytic and produce Shiga toxin
What is the name of the syndrome caused by Shiga toxins in humans?
Hemolytic uremic syndrome (HUS)
What is the target cell type for the Shiga toxin Stx2e in oedema disease in pigs?
Endothelial cells of the small arteries
What is the primary benefit of vaccination in preventing E. coli infections?
It reduces the predisposing factors for E. coli infections
What is the name of the gene responsible for the production of Shiga toxins in E. coli?
Shiga toxin gene (stx1 or stx2)
What is the preferred treatment for E. coli infections?
Hydration, oral electrolytes, and antimicrobial therapy
What is the name of the E. coli category that includes UPEC, SEPEC, and NTEC?
Extraintestinal pathogenic E. coli (ExPEC)
In dogs, what is the primary symptom of HUS?
Bloody diarrhea
What is the primary concern in treating severe mastitis caused by Escherichia coli?
LPS-induced shock
Which of the following antibiotics has been shown to have beneficial effects in treating MPEC infections?
Fluoroquinolones
What is the primary cause of the Metritis-Mastitis-Agalactiae (MMA) syndrome in pigs?
Multifactorial etiology
What is a common clinical sign of Post Partum Dysgalactiae Syndrome (PPDS) in pigs?
Reluctance to nurse
What is the effect of MMA syndrome on piglets?
Lower weight gain
What is the primary mechanism by which UPEC E. coli causes cellular destruction in the urinary tract?
Through the release of hemolysins that damage red blood cells and other cells
What is the purpose of administering antibiotics at night in the treatment of canine UTIs?
To target the increased bacterial activity at night
What is the primary difference between sporadic and recurrent UTIs in large animals?
Recurrent UTIs occur more frequently in large animals
What is the role of cranberry proanthocyanidins in the treatment of UTIs?
They inhibit the adhesion of E. coli to the uroepithelium
What is the primary cause of pyometra in bitches?
Hormonal changes in the female's reproductive tract
What is the percentage of pyometra cases in which E. coli is isolated?
58% to 88%
This quiz covers the pathogenesis of Enteropathogenic E. coli (EPEC), a type of Escherichia coli that causes intestinal infections. Learn about the mechanism of EPEC, its effects on humans and animals, and the role of pathogenicity islands.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
