Erythropoiesis-Stimulating Agents Dosage Quiz

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Questions and Answers

What is the most important factor responsible for anemia in CKD?

  • Blood loss during dialysis
  • Decreased erythropoietin production (correct)
  • Shorter life span of white blood cells
  • Iron deficiency

What is the prevalence of anemia among patients with a GFR less than 15 mL/minute?

  • 100%
  • 50%
  • 26%
  • 75% (correct)

When should the evaluation for anemia be initiated in CKD according to the text?

  • When hemoglobin is greater than 15 g/dL
  • When hemoglobin is less than 10 g/dL
  • When hemoglobin is less than 8 g/dL
  • When hemoglobin is less than 13 g/dL (men) or less than 12 g/dL (women) (correct)

Which of the following is a treatment for anemia in CKD as mentioned in the text?

<p>Erythropoiesis-stimulating agents (ESAs) (C)</p> Signup and view all the answers

What is the advantage of Methoxy polyethylene glycolProcrit and epoetin beta over Epoetin alfa?

<p>Less-frequent dosing (D)</p> Signup and view all the answers

What is the recommended dosage of erythropoiesis-stimulating agents (ESA) for non-dialysis patients with chronic kidney disease (CKD) when their hemoglobin is greater than 10 g/dL?

<p>Hold or reduce the dose (B)</p> Signup and view all the answers

When does the onset of hemoglobin increase occur after the initial dose of Mircera according to the text?

<p>7-15 days (A)</p> Signup and view all the answers

What is the most common cause of erythropoietin resistance in patients receiving ESA therapy for CKD?

<p>Iron deficiency (C)</p> Signup and view all the answers

What is the main cause of morbidity and mortality in patients undergoing dialysis due to chronic kidney disease-mineral and bone disorder (CKD-MBD)?

<p>Vascular calcification (B)</p> Signup and view all the answers

What are the consequences of CKD-MBD?

<p>Renal osteodystrophy and vascular calcification (A)</p> Signup and view all the answers

What is a recommended nondrug therapy for CKD-MBD?

<p>Restricting dietary phosphorus (C)</p> Signup and view all the answers

What is the therapy goal for erythropoiesis-stimulating agents in patients with CKD?

<p>To prevent blood transfusion (B)</p> Signup and view all the answers

What is the recommended cumulative or total dose of iron for adult patients undergoing dialysis?

<p>$1000 mg (B)</p> Signup and view all the answers

Which factor directly stimulates parathyroid hormone (PTH) secretion and elevates PTH concentrations in CKD-MBD?

<p>Hyperphosphatemia (C)</p> Signup and view all the answers

What should be monitored during erythropoietic therapy in patients with CKD?

<p>$1,25-dihydroxyvitamin D3 &amp; ferritin levels (C)</p> Signup and view all the answers

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