Erythropoiesis During Fetal and Postnatal Life
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Questions and Answers

What is the main cause of macrocytic anemia in case of vitamin B12 deficiency?

  • Normal functioning of erythroblasts
  • Increased life span of erythroblasts
  • Failure of nuclear maturation and division of erythroblasts (correct)
  • Decreased number of erythroblasts
  • How is vitamin B12 absorbed in the body?

  • By diffusion in the stomach
  • By binding to transferrin in the liver
  • Through passive absorption in the large intestine
  • Through active transport in the lower ileum with intrinsic factor (correct)
  • What is the specific role of intrinsic factor in the absorption of vitamin B12?

  • It binds to specific receptors in the lower ileum along with vitamin B12 (correct)
  • It binds to folic acid to enhance absorption
  • It converts vitamin B12 into a form suitable for absorption
  • It helps in the endocytosis of vitamin B12
  • Which deficiency also leads to macrocytic anemia and is similar in action to vitamin B12 deficiency?

    <p>Folic acid deficiency</p> Signup and view all the answers

    How does iron absorption occur in the body?

    <p>Through an active process in the lower ileum</p> Signup and view all the answers

    What must happen to dietary iron before it can be absorbed?

    <p>It must be reduced to Fe2+ form</p> Signup and view all the answers

    In iron absorption, what is the role of gastric HCl and vitamin C?

    <p>To convert Fe3+ into Fe2+ form for absorption</p> Signup and view all the answers

    What is the function of folic acid in relation to erythropoiesis?

    <p>Formation of hemoglobin</p> Signup and view all the answers

    How is folic acid deficiency related to anemia?

    <p>It causes macrocytic anemia</p> Signup and view all the answers

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