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Erythropoiesis During Fetal and Postnatal Life

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Erythropoiesis During Fetal and Postnatal Life

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Questions and Answers

What is the main cause of macrocytic anemia in case of vitamin B12 deficiency?

Normal functioning of erythroblasts
Increased life span of erythroblasts
Failure of nuclear maturation and division of erythroblasts (correct)
Decreased number of erythroblasts

How is vitamin B12 absorbed in the body?

By diffusion in the stomach
By binding to transferrin in the liver
Through passive absorption in the large intestine
Through active transport in the lower ileum with intrinsic factor (correct)

What is the specific role of intrinsic factor in the absorption of vitamin B12?

It binds to specific receptors in the lower ileum along with vitamin B12 (correct)
It binds to folic acid to enhance absorption
It converts vitamin B12 into a form suitable for absorption
It helps in the endocytosis of vitamin B12

Which deficiency also leads to macrocytic anemia and is similar in action to vitamin B12 deficiency?

Folic acid deficiency (A) Signup and view all the answers

How does iron absorption occur in the body?

Through an active process in the lower ileum (C) Signup and view all the answers

What must happen to dietary iron before it can be absorbed?

It must be reduced to Fe2+ form (C) Signup and view all the answers

In iron absorption, what is the role of gastric HCl and vitamin C?

To convert Fe3+ into Fe2+ form for absorption (D) Signup and view all the answers

What is the function of folic acid in relation to erythropoiesis?

Formation of hemoglobin (D) Signup and view all the answers

How is folic acid deficiency related to anemia?

It causes macrocytic anemia (A) Signup and view all the answers