Podcast
Questions and Answers
What is a characteristic feature of megaloblastic anemia?
What is a characteristic feature of megaloblastic anemia?
- Presence of hypersegmented neutrophils (correct)
- Increase in absolute reticulocyte count
- Decrease in RDW levels
- Decrease in LDH levels
Which test is a good indicator of accelerated hemolysis?
Which test is a good indicator of accelerated hemolysis?
- Leach phenotype test
- EMA binding test
- Confirmatory test for Hereditary Spherocytosis
- Autohemolysis test (correct)
What is a typical finding in Thrombotic Thrombocytopenic Purpura (TTP)?
What is a typical finding in Thrombotic Thrombocytopenic Purpura (TTP)?
- Presence of Schistocytes (correct)
- Normal platelet count
- Thrombocytosis
- High ADAMTS-13 levels
Which gene mutation is associated with Congenital Dyserythropoietic Anemia type 2 (CDA2)?
Which gene mutation is associated with Congenital Dyserythropoietic Anemia type 2 (CDA2)?
What is a confirmatory test for Paroxysmal Nocturnal Hemoglobinuria (PNH)?
What is a confirmatory test for Paroxysmal Nocturnal Hemoglobinuria (PNH)?
In Acquired Stomatocytosis, what are often seen as artifacts on Wright stain?
In Acquired Stomatocytosis, what are often seen as artifacts on Wright stain?
What is the main reason hematopoietic stem cells (HSCs) can produce all lineages of blood cells throughout an individual's lifetime?
What is the main reason hematopoietic stem cells (HSCs) can produce all lineages of blood cells throughout an individual's lifetime?
Approximately how many erythrocytes can bone marrow estimate producing per kg of body weight?
Approximately how many erythrocytes can bone marrow estimate producing per kg of body weight?
What is the estimated production of platelets per kg of body weight by bone marrow?
What is the estimated production of platelets per kg of body weight by bone marrow?
Which characteristic is NOT a criterion for red blood cell maturation?
Which characteristic is NOT a criterion for red blood cell maturation?
What is the approximate duration taken by a BFU-E (burst-forming unit-erythroid) to mature?
What is the approximate duration taken by a BFU-E (burst-forming unit-erythroid) to mature?
What is the pathophysiological mechanism behind the formation of platelet vWF thrombi in TTP?
What is the pathophysiological mechanism behind the formation of platelet vWF thrombi in TTP?
Which diagnostic test is commonly used for pernicious anemia?
Which diagnostic test is commonly used for pernicious anemia?
What type of Hemoglobin mutation is associated with Hgb S?
What type of Hemoglobin mutation is associated with Hgb S?
Which virus can cause a transient aplastic crisis in chronic hemolytic anemia?
Which virus can cause a transient aplastic crisis in chronic hemolytic anemia?
What is the characteristic feature of AIHA (Autoimmune Hemolytic Anemia)?
What is the characteristic feature of AIHA (Autoimmune Hemolytic Anemia)?
Which condition results in the increase in the number of spherocytes in the blood?
Which condition results in the increase in the number of spherocytes in the blood?
What is the most preferable site for an adult to collect bone marrow?
What is the most preferable site for an adult to collect bone marrow?
Which phospholipid flips into the outer leaflet, playing a role in cell signaling?
Which phospholipid flips into the outer leaflet, playing a role in cell signaling?
Where is the location of MN blood group antigens?
Where is the location of MN blood group antigens?
Which chromosome location harbors the Alpha and Zeta genes?
Which chromosome location harbors the Alpha and Zeta genes?
What is the primary physiological response to increased anemia demand?
What is the primary physiological response to increased anemia demand?
Which hormone is the master regulator of iron metabolism with a negative effect on RBC production?
Which hormone is the master regulator of iron metabolism with a negative effect on RBC production?
What initiates an intracellular message to developing erythroid cells?
What initiates an intracellular message to developing erythroid cells?
Where does iron need to be in order for hemoglobin to combine with oxygen?
Where does iron need to be in order for hemoglobin to combine with oxygen?
What physiological response occurs to meet the demand for increased anemia?
What physiological response occurs to meet the demand for increased anemia?
What is characteristic of Hematopoietic Stem Cells (HSCs)?
What is characteristic of Hematopoietic Stem Cells (HSCs)?
What is the primary regulator of erythropoiesis and where is it produced?
What is the primary regulator of erythropoiesis and where is it produced?
Which structure of hemoglobin has iron in the ferric state and is unable to carry oxygen?
Which structure of hemoglobin has iron in the ferric state and is unable to carry oxygen?
What is the main function of the enzyme GSH in red blood cells?
What is the main function of the enzyme GSH in red blood cells?
Which component is mainly responsible for lateral distribution during the passage of red blood cells through narrow capillaries?
Which component is mainly responsible for lateral distribution during the passage of red blood cells through narrow capillaries?
What is the integral protein responsible for anchoring Band 3 and Protein 4.2 in red blood cells?
What is the integral protein responsible for anchoring Band 3 and Protein 4.2 in red blood cells?
What happens to red blood cells when phospholipids redistribute to the outer layer?
What happens to red blood cells when phospholipids redistribute to the outer layer?