Erythrocytes and Their Functions
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Questions and Answers

What is the primary function of erythrocytes?

  • Producing antibodies
  • Transporting nutrients in the blood
  • Fighting infections in the body
  • Carrying oxygen in the blood (correct)

Which protein is responsible for carrying oxygen in erythrocytes?

  • Hemoglobin (correct)
  • Spectrin
  • Glycophorin A
  • Band 3 protein

What is the composition of the erythrocyte plasmalemma?

  • 50% lipid, 30% carbohydrate, 20% protein
  • 30% lipid, 20% carbohydrate, 50% protein
  • 60% lipid, 10% carbohydrate, 30% protein
  • 40% lipid, 10% carbohydrate, 50% protein (correct)

What is the basis for the ABO blood typing system?

<p>Antigenic sites on glycophorin A (D)</p> Signup and view all the answers

What forms a lattice bound to underlying actin filaments in erythrocytes?

<p>Spectrin (D)</p> Signup and view all the answers

Where do erythrocytes frequently assume a cuplike shape according to in vivo observations?

<p>At the angles of capillary bifurcations (A)</p> Signup and view all the answers

What is the main function of the submembranous meshwork mentioned in the text?

<p>Stabilizing the membrane and maintaining cell shape (A)</p> Signup and view all the answers

What is the primary function of hemoglobin in erythrocytes?

<p>Carrying oxygen and carbon dioxide (C)</p> Signup and view all the answers

What is the primary source of energy for erythrocytes?

<p>Anaerobic glycolysis (C)</p> Signup and view all the answers

What causes the removal of senescent or worn-out erythrocytes from circulation?

<p>Defects in the membrane's cytoskeletal lattice or ion transport systems (D)</p> Signup and view all the answers

What is the average lifespan of human erythrocytes in circulation?

<p>120 days (B)</p> Signup and view all the answers

What is the main function of macrophages in relation to RBCs?

<p>Recognition and removal of senescent RBCs (C)</p> Signup and view all the answers

Which major groups are leukocytes divided into based on the density of their cytoplasmic granules?

<p>Granulocytes and agranulocytes (C)</p> Signup and view all the answers

What distinguishes granulocytes from agranulocytes?

<p>Presence of distinct lobes in the nucleus (D)</p> Signup and view all the answers

What is the primary characteristic feature of granulocytes?

<p>Abundant cytoplasmic granules (C)</p> Signup and view all the answers

How do granulocytes generate energy for their needs?

<p>Depend largely on glycolysis (B)</p> Signup and view all the answers

What is the estimated lifespan of granulocytes?

<p>Only a few days (B)</p> Signup and view all the answers

What happens to most granulocytes in the connective tissue?

<p>Undergo apoptosis (A)</p> Signup and view all the answers

What is the role of macrophages in removing cellular debris?

<p>They remove the debris without causing an inflammatory response (C)</p> Signup and view all the answers

What is the shape of the nucleus in agranulocytes?

<p>Spherical (D)</p> Signup and view all the answers

What causes leukocytes to slow down and attach to the endothelium in venules?

<p>P-selectin on endothelial cells (B)</p> Signup and view all the answers

What is the process called when leukocytes send extensions through the openings between endothelial cells?

<p>Diapedesis (C)</p> Signup and view all the answers

What triggers the attraction of neutrophils to bacteria?

<p>Chemotaxis (B)</p> Signup and view all the answers

Where do leukocytes migrate during diapedesis?

<p>Out of the venules into the surrounding tissue space (B)</p> Signup and view all the answers

What is released from various sources to trigger loosening of intercellular junctions in endothelial cells?

<p>Cytokines (D)</p> Signup and view all the answers

What is the role of P-selectin in the interaction between leukocytes and endothelial cells?

<p>Causes leukocytes to slow down and attach to the endothelium (A)</p> Signup and view all the answers

What is the range of leukocytes in healthy adults per microliter of blood?

<p>4000-10000 (C)</p> Signup and view all the answers

What do all leukocytes contribute to in the body?

<p>Defense against invading microorganisms and tissue repair (D)</p> Signup and view all the answers

Flashcards

Erythrocyte function

Carrying oxygen in the blood.

Oxygen carrier protein

Hemoglobin.

Erythrocyte membrane composition

40% lipid, 10% carbohydrate, 50% protein.

ABO blood typing basis

Antigenic sites on glycophorin A.

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Erythrocyte shape support

Spectrin forms a lattice bound to actin filaments.

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Erythrocyte shape in capillaries

Cuplike shape at capillary bifurcations.

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Submembranous meshwork function

Stabilizes membrane, maintains shape.

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Hemoglobin's role

Carries oxygen and carbon dioxide.

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Erythrocyte energy source

Anaerobic glycolysis.

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Senescent erythrocyte removal

Defects in membrane cytoskeleton or ion transport.

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Erythrocyte lifespan

120 days.

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Macrophage role in RBCs

Recognize and remove senescent RBCs.

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Leukocyte groups

Granulocytes and agranulocytes.

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Granulocyte vs. agranulocyte difference

Presence of distinct lobes in nucleus.

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Granulocyte characteristic

Abundant cytoplasmic granules.

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Granulocyte energy source

Mostly glycolysis.

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Granulocyte lifespan

A few days.

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Granulocyte fate

Apoptosis in connective tissue.

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Macrophage debris role

Remove debris without inflammation.

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Agranulocyte nucleus shape

Spherical.

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Leukocyte slow-down trigger

P-selectin on endothelial cells.

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Leukocyte movement through endothelium

Diapedesis.

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Neutrophil attraction trigger

Chemotaxis.

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Leukocyte migration location

Surrounding tissue space.

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Intercellular junction loosening trigger

Cytokines.

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P-selectin role

Causes leukocytes to slow and attach to endothelium.

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Leukocyte count range

4000-10000 per microliter.

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Leukocyte body function

Defense and tissue repair.

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