Erythrocyte Sedimentation Rate (ESR) Test
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Questions and Answers

What is the purpose of placing the tube in an isolated area in the laboratory that is free from vibrations?

  • To speed up the process of erythrocyte sedimentation
  • To prevent interference with the erythrocyte sedimentation rate (ESR) measurement (correct)
  • To avoid contamination of the blood sample
  • To increase the accuracy of the hemolysis test

What can be a source of error in the Westergren method for measuring ESR?

  • Normal ESR values
  • Presence of red blood cell abnormalities
  • Increased plasma viscosity (correct)
  • Refrigeration of the blood sample

Why is it important to ensure that a standard amount of anticoagulant was used in the ESR test?

  • To avoid hemolysis of the blood sample
  • To regulate room temperature near 20°C
  • To increase the erythrocyte sedimentation rate
  • To prevent false high results due to increased anticoagulant (correct)

What would be the effect of polycythemia on the erythrocyte sedimentation rate (ESR)?

<p>Increase in ESR (B)</p> Signup and view all the answers

What is the role of plasma albumin in the sedimentation of RBCs?

<p>Retardation of RBC sedimentation (A)</p> Signup and view all the answers

What is the erythrocyte sedimentation rate (ESR) a measure of?

<p>Inflammation (A)</p> Signup and view all the answers

Which method is used for the measurement of ESR manually?

<p>Wintrobe method (C)</p> Signup and view all the answers

What is the purpose of the Westergren tube in the measurement of ESR?

<p>To measure the distance RBCs fall in one hour (B)</p> Signup and view all the answers

What is the Wintrobe Set used for in the measurement of ESR?

<p>To calibrate the mm scale (B)</p> Signup and view all the answers

What does an ESR test help in detecting?

<p>Inflammation caused by infections or autoimmune diseases (B)</p> Signup and view all the answers

Flashcards

Erythrocyte Sedimentation Rate (ESR)

A laboratory test that measures the rate at which red blood cells settle in a tube of blood over one hour.

High ESR

A high ESR can indicate inflammation, infection, or autoimmune diseases.

Low ESR

A low ESR can occur in individuals with low levels of inflammation or certain medical conditions.

Westergren Method

The Westergren method is a standard way of measuring the ESR. It involves using a special tube called a Westergren tube and timing how long it takes for red blood cells to fall a certain distance.

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Standardization of ESR

The measurement of the ESR should be standardized to ensure consistent results between different laboratories.

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Vibrations and ESR

The Westergren method requires careful handling to prevent vibrations, which can affect the accuracy of the results.

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Plasma Viscosity and ESR

Plasma viscosity, the thickness of the blood plasma, can affect the speed of sedimentation.

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Anticoagulant and ESR

Excess anticoagulant can lead to a falsely elevated ESR because it increases plasma viscosity.

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Increased ESR Causes

An increased ESR can indicate conditions like anemia, dehydration, or certain types of cancer.

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Plasma Albumin and ESR

A protein in the blood that helps to keep red blood cells from settling too quickly.

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Study Notes

Importance of Laboratory Conditions

  • The tube is placed in an isolated area in the laboratory to minimize vibrations that can affect the accuracy of the ESR measurement.

Sources of Error in Westergren Method

  • Vibrations can be a source of error in the Westergren method for measuring ESR.
  • Other sources of error include variation in anticoagulant amount and improper tube handling.

Importance of Standard Anticoagulant Amount

  • Using a standard amount of anticoagulant is crucial in the ESR test to ensure accurate results, as variations can affect the measurement.

Effect of Polycythemia on ESR

  • Polycythemia, a condition characterized by an increased number of RBCs, can decrease the ESR due to the increased RBC aggregation.

Role of Plasma Albumin in RBC Sedimentation

  • Plasma albumin helps to inhibit the aggregation of RBCs, which in turn affects the sedimentation rate.

Erythrocyte Sedimentation Rate (ESR)

  • ESR is a measure of the rate at which RBCs settle at the bottom of a vertical tube, usually measured in mm/h.
  • It is a non-specific indicator of inflammation and can be affected by various factors.

Measurement of ESR

  • The Westergren method is commonly used for manual measurement of ESR.
  • The Wintrobe Set is also used for the measurement of ESR.
  • The Westergren tube is a special tube used in the measurement of ESR, with a precise volume and dimensions.

Purpose of ESR Test

  • An ESR test helps detect inflammation, infection, and autoimmune disorders.

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Description

Test your knowledge about the Erythrocyte Sedimentation Rate (ESR), a common hematology test used as a non-specific measure of inflammation. Learn about the procedure and interpretation of results for this important test.

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