Erosive Lichen Planus Diagnosis and Treatment

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38 Questions

What is the primary reason for performing a biopsy in erosive lichen planus?

To rule out neoplasm

What is the typical timeframe for the development of chemotherapy-related ulceration?

Within 1-2 weeks

What is the primary goal of treatment for chronic oral ulcers?

To make the patient comfortable

Which of the following is a common feature of oral Crohn's disease?

It is often a solitary lesion

What is the purpose of removing precipitating factors in erosive lichen planus?

To alleviate symptoms

What is the primary concern in managing chemotherapy-related ulceration?

Managing nutrition and hydration

What is the role of a dentist in managing oral Crohn's disease?

To provide supportive care and refer the patient to a specialist

What is the typical outcome of chemotherapy-related ulceration after chemotherapy is completed?

The ulceration resolves

What is the primary cause of Focal/Frictional Hyperkeratosis?

Chronic irritation at a specific site

In which individuals is Oral Hairy Leukoplakia commonly seen?

Immune-suppressed individuals

What is the characteristic appearance of Nicotinic Stomatitis?

Red dots on the palate with surrounding white keratotic rings

What is a characteristic of a submucosal hemorrhage?

Does not blanch with pressure

What is a treatment option for Hemangioma and Vascular Malformation?

Laser

What is the primary goal of the biopsy in Oral Hairy Leukoplakia?

To diagnose Epstein-Barr Virus infection

What is a complication of Vascular Malformation of the Jaws?

All of the above

What is the treatment for Nicotinic Stomatitis?

Tobacco/smoking cessation and continued observation

What is the characteristic of Idiopathic Leukoplakia?

No identifiable cause or underlying factor

What is the purpose of aspirating before incision in a Vascular Malformation of the Jaws?

To assess the vascularity of the lesion

What is used to image Vascular Malformations?

Conventional angiography and Magnetic Resonance Angiogram (MRA)

What is the treatment for Focal/Frictional Hyperkeratosis?

Remove the underlying cause/irritation

What is a sclerosing agent used to treat Vascular Malformations?

All of the above

What is the common location of Oral Hairy Leukoplakia?

Lateral border of the tongue

What is the primary cause of Physiologic Pigmentation in darker skinned individuals?

Normal variation in melanin production

Which of the following is a characteristic of Classic KS?

Milder and with few issues

What is the main treatment for Smoker's Melanosis?

Smoking cessation

Which of the following drugs is NOT associated with Drug-Induced Pigmentation?

Aspirin

What is the primary mechanism of Drug-Induced Pigmentation?

Stimulation of melanin production

What is the preferred type of retainer in prosthetic management for Sjögren's syndrome?

Non-tissue bearing full coverage retainer

Which of the following heavy metals is associated with Heavy Metal Staining?

Gold

What is the primary treatment for Post-Inflammatory/Reactive Pigmentation?

Treatment of the underlying mucocutaneous disorder

What is a common oral complication associated with Sjögren's syndrome?

Dysgeusia

What is the primary goal of dietary counseling in managing Sjögren's syndrome?

To stimulate salivary flow

What is the mechanism of action of pilocarpine (Salagen®) in stimulating salivary flow?

Cholinergic agonist

What is the characteristic of Post-Inflammatory/Reactive Pigmentation?

Increased melanin production and deposition due to trauma or inflammation

What is the common characteristic of symptoms experienced by patients with burning mouth syndrome?

Burning, scaly, hot, and prickly

What is the primary component of oral lubricants used in managing Sjögren's syndrome?

Glycerin

What is the purpose of fluoride trays in managing Sjögren's syndrome?

To remineralize tooth enamel

What is the common feature of oral hygiene products that can exacerbate Sjögren's syndrome?

Eugenol content

Study Notes

Erosive Lichen Planus

  • Biopsy is necessary to confirm diagnosis
  • May transform into neoplasm if left untreated
  • Removal of precipitating factors such as food, mouth care products, medications, and stresses is crucial
  • Palliative care may be necessary for chronic lesions, and topical steroids may be considered

Oral Crohn's Disease

  • Consult with MD, as it may be the first presentation
  • Eliminate aggravating factors such as diet
  • Treatment may be directed by the GI or rheumatology specialist, with support from DDS
  • Affects rapidly dividing cells in the mucosa, leading to ulceration within 1-2 weeks
  • Superinfection may occur due to immune compromise
  • Palliative care is necessary, including hydration, vitamin supplementation, and oral mouth rinse (Tantum)
  • Ulcerations usually resolve after chemotherapy is complete

General Approach to Ulcers

  • Duration and previous incidence should be considered
  • Remove suspected causes and make patients comfortable
  • Close monitoring and follow-up are necessary
  • Biopsy and referral may be necessary

Chronic Oral Ulcers

  • Categories of ulcers include acute (single or multiple) and chronic (single or multiple)
  • Focal/Frictional Hyperkeratosis occurs due to trauma, leading to increased keratin production
  • Treatment involves removing the underlying cause or irritation

Oral Hairy Leukoplakia

  • Caused by Epstein-Barr Virus infection in immune-suppressed individuals
  • Seen on the lateral border of the tongue
  • Diagnosis involves biopsy, and treatment includes antiviral meds and excision for limited areas

Nicotinic Stomatitis

  • Caused by tobacco smoking, particularly pipe smoking
  • Characterized by red dots on the palate with surrounding white keratotic rings (halo)
  • Treatment involves tobacco cessation, and biopsy if no resolution

Idiopathic Leukoplakia

  • Characterized by white patches due to chronic irritation from substances like EtOH, tobacco, and HPV
  • Treatment involves removing the source of irritation and close observation

Hemangioma vs. Vascular Malformation

  • Vascular malformation is limited in extent and easier to manage
  • Treatment options include laser, resection, and magnetic resonance angiogram (MRA)
  • Hemangioma of the jaws can be life-threatening and requires high caution

Submucosal Hemorrhage

  • Characterized by well-demarcated, red to red-brown to pale brown lesions
  • Caused by trauma, pressure, surgery, and coughing
  • Seen in anticoagulated patients and those with underlying medical conditions

Physiologic Pigmentation

  • Seen in darker-skinned individuals
  • Characterized by diffuse brownish epithelial pigmentation in the gingiva and buccal mucosa
  • No treatment is necessary

Post-Inflammatory/Reactive Pigmentation

  • Seen in susceptible individuals due to trauma or inflammation
  • Characterized by increased melanin production and deposition
  • Resolution occurs once the trigger is removed

Smoker's Melanosis

  • Characterized by diffuse hyperpigmentation due to prolonged tobacco use
  • Treatment involves smoking cessation, but may not guarantee resolution

Drug-Induced Pigmentation

  • Characterized by diffuse mucosal and/or cutaneous pigmentation
  • Caused by chronic drug use, stimulating melanin production
  • Treatment involves stopping the causative drug

Heavy Metal Staining

  • Characterized by deposition of heavy metals like lead, mercury, and gold
  • Biopsy can show lymphocytic infiltrate in the case of Sjögren's
  • Treatment involves removing the source of heavy metal exposure

This quiz covers the diagnosis and treatment of erosive lichen planus, including biopsy confirmation, removal of precipitating factors, and palliative care. It also touches on the potential for transformation into neoplasms, such as squamous cell carcinoma.

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