Ergotamine Patient Teaching Quiz
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Questions and Answers

Match the triptan medication with its route of administration:

Sumatriptan = Nasal spray Rizatriptan = Conventional tablet Zolmitriptan = Inhaler Almotriptan = Disintegrating tablet

Match the triptan medication with its potential adverse reactions:

Sumatriptan = Increased blood pressure Naratriptan = Drowsiness Eletriptan = Muscle pain Frovatriptan = Sweating

Match the triptan medication with its effect onset time after oral dosing:

Sumatriptan = 20-60 minutes Naratriptan = 20-60 minutes Rizatriptan = 20-60 minutes Zolmitriptan = 20-60 minutes

Match the triptan medication with its contraindication:

<p>Sumatriptan = Ischemic heart disease Naratriptan = Ischemic heart disease Rizatriptan = Ischemic heart disease Zolmitriptan = Ischemic heart disease</p> Signup and view all the answers

Match the triptan medication with its use in patients experiencing nausea and vomiting:

<p>Sumatriptan = Yes Naratriptan = Yes Rizatriptan = Yes Zolmitriptan = Yes</p> Signup and view all the answers

Match the triptan medication with its potential interaction with St. John’s wort:

<p>Sumatriptan = Possible Naratriptan = Possible Rizatriptan = Possible Zolmitriptan = Possible</p> Signup and view all the answers

Match the mechanism of action with the corresponding component of the combination medication:

<p>Unknown = Acetaminophen Inhibits prostaglandin synthesis = Aspirin Stimulates the CNS, cardiac activity, and diuresis = Caffeine Induces vascular constriction and increases the effectiveness of acetaminophen and aspirin by approximately 40% = Caffeine</p> Signup and view all the answers

Match the adverse effects with the corresponding component of the combination medication:

<p>Hepatic impairment = Acetaminophen GI effects and toxicity = Aspirin Cardiovascular effects and restlessness = Caffeine Potential hepatotoxicity = Acetaminophen</p> Signup and view all the answers

Match the contraindications with the corresponding aspect of the combination medication:

<p>Allergies to the individual drugs = Combination medication Impaired hepatic function = Combination medication Chronic alcoholism = Combination medication Pregnancy and lactation = Combination medication</p> Signup and view all the answers

Match the assessment considerations with the corresponding aspect of the combination medication:

<p>Monitoring for diminished pain using a pain scale = Therapeutic effects post-administration Assessing for adverse effects such as hepatotoxicity and allergic reaction = Post-administration assessment Assessing for adverse effects such as fluid and electrolyte imbalance, hypoglycemia, and cardiovascular effects = Post-administration assessment Vigilance in patients with renal impairment, diabetes, cardiovascular disease, and pregnant or lactating individuals = Use in specific patient populations</p> Signup and view all the answers

Match the considerations for administration with the corresponding aspect of the combination medication:

<p>Children older than 12 years may receive the adult dose = Dosing People with hepatic impairment should not use it on an ongoing basis = Dosing Nurses should be familiar with all aspects of each medication for safe administration = Administration Vigilance is warranted when using the combination medication in specific patient populations = Administration</p> Signup and view all the answers

Match the drug interactions with the corresponding aspect of the combination medication:

<p>Increased or decreased effects with specific medications = Interactions Potential risk for adverse effects like vasoconstriction, seizure activity, and decreased diuretic effects = Interactions Specific medications that increase or decrease the effects of acetaminophen, aspirin, and caffeine = Interactions Important information for preventing interactions = Interactions</p> Signup and view all the answers

Match the pain medication with its specific pharmacokinetic characteristic:

<p>Naproxen sodium = Rapid absorption and analgesic effects Naproxen = Nonselective inhibitor of cyclooxygenase, inhibiting prostaglandin synthesis of COX-1 and COX-2 Ketorolac tromethamine = Frequently administered intravenously in emergency departments for migraine treatment Acetaminophen, aspirin, and caffeine combination = Effective for headaches</p> Signup and view all the answers

Match the adverse effect of pain medication with its specific warning or caution:

<p>Naproxen sodium = BLACK BOX WARNING from the FDA Naproxen = Caution advised for patients with renal or hepatic impairment Tricyclic drugs = Reversal of central sensitization and chronicity of headaches Botulinum toxin type A = Small decrease in the number of headaches per month, not statistically significant</p> Signup and view all the answers

Match the group of patients with the contraindications for pain medication:

<p>Naproxen or naproxen sodium = Known allergies, pregnancy, lactation, asthma, cardiovascular dysfunction, hypertension, GI bleeding, and peptic ulcer Ketorolac tromethamine = Frequently administered intravenously in emergency departments for migraine treatment Acetaminophen, aspirin, and caffeine combination = Specific pharmacokinetics, including peak of action, half-life, metabolism, and excretion, crossing the placental barrier and entering breast milk Tricyclic drugs = Reversal of central sensitization and chronicity of headaches</p> Signup and view all the answers

Match the nursing implication with the pain medication:

<p>Naproxen sodium = Assessing for therapeutic and adverse effects, and providing patient teaching Naproxen = Improves solubility for faster absorption Ketorolac tromethamine = Frequently administered intravenously in emergency departments for migraine treatment Botulinum toxin type A = Small decrease in the number of headaches per month, not statistically significant</p> Signup and view all the answers

Match the pain medication with the specific patient population for dosage caution:

<p>Naproxen sodium = Older people should not take more than 200 mg every 12 hours Naproxen = Both metabolized in the liver with a half-life of 12 to 15 hours Ketorolac tromethamine = Frequently administered intravenously in emergency departments for migraine treatment Acetaminophen, aspirin, and caffeine combination = Specific pharmacokinetics, including peak of action, half-life, metabolism, and excretion, crossing the placental barrier and entering breast milk</p> Signup and view all the answers

Match the pain medication with its association with another drug:

<p>Naproxen sodium = Increases lithium levels and the risk of lithium toxicity when administered with lithium Naproxen = A nonselective inhibitor of cyclooxygenase, inhibiting prostaglandin synthesis of COX-1 and COX-2 Ketorolac tromethamine = Frequently administered intravenously in emergency departments for migraine treatment Botulinum toxin type A = Small decrease in the number of headaches per month, not statistically significant</p> Signup and view all the answers

Match the following statements with their corresponding information about ergotamine:

<p>Ergotamine is metabolized by CYP3A4 = Metabolized by CYP3A4 Ergotamine has interactions with alpha and beta-adrenergic blockers = Interactions with alpha and beta-adrenergic blockers Ergotamine is administered sublingually = Administered sublingually Ergotamine should not be given to children or those with renal or hepatic impairment = Contraindicated for children or those with renal or hepatic impairment</p> Signup and view all the answers

Match the following statements with their corresponding patient teaching guidelines for ergotamine use:

<p>Patients should avoid over-the-counter medications with acetaminophen = Patient teaching for acetaminophen–aspirin–caffeine combinations Patients should not eat, drink, or smoke while the medication is being dissolved = Guidelines for administering ergotamine Foods that increase the effect of ergotamine include cola, coffee, tea, and grapefruit juice = Information about foods affecting ergotamine Patients should be assessed for therapeutic effectiveness when using ergotamine = Assessment guidelines for patients using ergotamine</p> Signup and view all the answers

Match the following adverse effects with their corresponding information about ergotamine:

<p>Ergotamine has cardiovascular and musculoskeletal effects = Adverse effects of ergotamine Caution is advised when administering ergotamine to older adults due to its vasoconstrictive properties and cardiovascular adverse effects = Caution for administering ergotamine to older adults The FDA has issued a black box warning regarding the contraindications and interactions of ergotamine = Black box warning about ergotamine Ergotamine has several contraindications including hypersensitivity, peripheral vascular disease, and pregnancy = Contraindications of ergotamine</p> Signup and view all the answers

Match the following information about ergotamine with their corresponding usage:

<p>Ergotamine is ordered to prevent or stop migraine, cluster, or vascular headaches = Usage of ergotamine Ergotamine's peak action is 0.5 to 3 hours with a half-life of 2 hours = Peak action and half-life of ergotamine Ergotamine is excreted in breast milk and has caused fetal growth retardation in animal studies = Excretion and fetal effects of ergotamine Triptans are considered more effective than ergotamine for abortive therapy for migraine headaches = Comparison with triptans for migraine therapy</p> Signup and view all the answers

Match the following statements with their corresponding nursing implications for ergotamine use:

<p>Ergotamine has interactions with azole antifungals and other medications = Interactions of ergotamine with medications Ergotamine is contraindicated with potent CYP3A4 inhibitors = Contraindications of ergotamine with specific inhibitors Patients should be monitored for adverse effects when using ergotamine = Monitoring guidelines for patients using ergotamine Ergotamine has several nursing implications, including the need to prevent interactions and monitor for adverse effects = Nursing implications for ergotamine use</p> Signup and view all the answers

Match the following information about ergotamine with their corresponding cautionary advice:

<p>Ergotamine is contraindicated with pregnancy = Contraindication of ergotamine with pregnancy Ergotamine is contraindicated with peripheral vascular disease = Contraindication of ergotamine with peripheral vascular disease Caution is advised when administering ergotamine to older adults due to its vasoconstrictive properties and cardiovascular adverse effects = Caution for administering ergotamine to older adults Ergotamine is contraindicated with potent CYP3A4 inhibitors = Contraindication of ergotamine with specific inhibitors</p> Signup and view all the answers

Match the medication with its appropriate application in the treatment of migraine:

<p>Ergotamine preparations = May be effective in aborting the headache if taken early in the migraine process Triptan medications = Administered for the treatment of migraine headaches NSAIDs = Used in the treatment of migraine headaches Antiepileptics = Part of prophylactic treatment of migraine</p> Signup and view all the answers

Match the medication with its potential side effects in the treatment of migraine:

<p>Ergotamine preparations = Side effects include aching muscles, paresthesias, nausea, and vomiting Triptan medications = May produce nervousness and dizziness NSAIDs = No specific side effects mentioned Antiepileptics = No specific side effects mentioned</p> Signup and view all the answers

Match the type of headache with its corresponding recommended treatment:

<p>Cluster headaches = Involves subcutaneous sumatriptan and high-flow (100%) oxygen Migraine headaches = Guided by several factors and includes abortive and preventive therapy Tension-Type headaches = Acute therapy includes nonpharmacologic methods and medication Cranial arteritis = Consists of early administration of a corticosteroid and analgesic agents</p> Signup and view all the answers

Match the medication with its application in the treatment of cluster headaches:

<p>100% oxygen by facemask = Part of the medical management of an acute attack of cluster headaches Subcutaneous sumatriptan = Used in the treatment of acute cluster headaches Intranasal zolmitriptan = Part of the medical management of an acute attack of cluster headaches Calcitonin gene–related peptides (CGRPs) monoclonal antibodies = Approved by the U.S. FDA for migraine prevention</p> Signup and view all the answers

Match the medication with its application in the prophylactic treatment of migraine:

<p>Beta-blockers = Used in the prophylactic treatment of migraine Antidepressants = Part of prophylactic treatment of migraine Angiotensin-converting enzyme (ACE) inhibitors = Part of prophylactic treatment of migraine Angiotensin receptor blockers = Part of prophylactic treatment of migraine</p> Signup and view all the answers

Match the medication with its application in the treatment of long-term migraine:

<p>Triptans = Initial pharmacotherapy for acute treatment of migraine Intravenous metoclopramide and prochlorperazine = Used in eligible adults who present to an emergency department with acute migraine Ketorolac = Highly effective in relieving migraine-associated symptoms in children Steroid injections and calcium channel blockers = May offer an option in the treatment of long-term migraine</p> Signup and view all the answers

Match the medication with its usage in migraine treatment:

<p>Ergotamine preparations = Effective in aborting migraines Triptan medications = Should not be taken concurrently with ergotamine NSAIDs, antispasmodic agents, and neuroleptics = Nonspecific medications for migraine treatment CGRP monoclonal antibodies = Approved by the FDA for migraine prevention</p> Signup and view all the answers

Match the medication with its usage in cluster headache management:

<p>100% oxygen = May be involved in cluster headache management Subcutaneous sumatriptan = May offer options for cluster headache treatment Intranasal zolmitriptan = May be involved in cluster headache management Steroid injections and calcium channel blockers = May be involved in cluster headache treatment</p> Signup and view all the answers

Match the medication with its usage in abortive therapy for migraines:

<p>NSAIDs, acetaminophen–aspirin with caffeine = Involved in abortive therapy for migraines Ergot alkaloids = Involved in abortive therapy for migraines Triptans = Involved in abortive therapy for migraines Antiepileptics = Used in prophylactic treatment for migraines</p> Signup and view all the answers

Match the medication with its usage in preventive therapy for migraines:

<p>Beta-blockers = Used in prophylactic treatment for migraines Antiepileptics = Used in prophylactic treatment for migraines Antidepressants = Used in prophylactic treatment for migraines ACE inhibitors and angiotensin receptor blockers = Used in prophylactic treatment for migraines</p> Signup and view all the answers

Match the medication with its usage in tension-type headache acute therapy:

<p>Nonpharmacologic methods = Used in tension-type headache acute therapy Acetaminophen, aspirin, and NSAIDs = Used in tension-type headache acute therapy Ergot alkaloids = Not used in tension-type headache acute therapy Triptans = Not used in tension-type headache acute therapy</p> Signup and view all the answers

Match the medication with its effect on cranial blood vessels:

<p>Ergotamine tartrate = Causes prolonged constriction of cranial blood vessels Triptan medications = May result in potential prolonged vasoactive reaction NSAIDs = Do not have direct effect on cranial blood vessels CGRP monoclonal antibodies = Do not have direct effect on cranial blood vessels</p> Signup and view all the answers

Study Notes

Patient Teaching and Use of Ergotamine

  • Patient teaching guidelines for acetaminophen–aspirin–caffeine combinations include avoiding over-the-counter medications with acetaminophen and reporting certain symptoms to a healthcare provider
  • Ergotamine preparations are used for abortive therapy for migraine headaches, but triptans are considered more effective
  • Ergotamine's peak action is 0.5 to 3 hours with a half-life of 2 hours, metabolized by CYP3A4, excreted in breast milk, and has caused fetal growth retardation in animal studies
  • Ergotamine is ordered to prevent or stop migraine, cluster, or vascular headaches and should not be given to children or those with renal or hepatic impairment
  • Caution is advised when administering ergotamine to older adults due to its vasoconstrictive properties and cardiovascular adverse effects
  • Adverse effects of ergotamine include cardiovascular and musculoskeletal effects, and it has several contraindications including hypersensitivity, peripheral vascular disease, and pregnancy
  • Ergotamine is contraindicated with potent CYP3A4 inhibitors and has interactions with alpha and beta-adrenergic blockers, azole antifungals, and other medications
  • Foods that increase the effect of ergotamine include cola, coffee, tea, and grapefruit juice
  • Ergotamine is administered sublingually and should not be crushed, chewed, or swallowed whole, and patients should not eat, drink, or smoke while the medication is being dissolved
  • Patients should be assessed for therapeutic effectiveness when using ergotamine
  • Ergotamine has several nursing implications, including the need to prevent interactions and monitor for adverse effects
  • The FDA has issued a black box warning regarding the contraindications and interactions of ergotamine

Headache Management and Treatment Summary

  • Ergotamine preparations can be effective in aborting migraines and are low in cost.
  • Ergotamine tartrate acts on smooth muscle, causing prolonged constriction of cranial blood vessels.
  • Triptan medications should not be taken concurrently with ergotamine due to potential prolonged vasoactive reaction.
  • Other nonspecific medications for migraine treatment include NSAIDs, antispasmodic agents, and neuroleptics.
  • Prophylactic treatment for migraines includes beta-blockers, antiepileptics, antidepressants, ACE inhibitors, and angiotensin receptor blockers.
  • CGRP monoclonal antibodies erenumab, fremanezumab, and galcanezumab are approved by the FDA for migraine prevention.
  • Cluster headache management may involve 100% oxygen, subcutaneous sumatriptan, or intranasal zolmitriptan.
  • High-flow oxygen may be administered for 15 minutes to determine effectiveness in cluster headaches.
  • Steroid injections and calcium channel blockers may offer options for cluster headache treatment.
  • Abortive therapy for migraines involves medications like NSAIDs, acetaminophen–aspirin with caffeine, ergot alkaloids, and triptans.
  • Preventive therapy for migraines aims to prevent the development of migraine headaches.
  • Tension-type headache acute therapy includes nonpharmacologic methods and medication like acetaminophen, aspirin, and NSAIDs.

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Test your knowledge on patient teaching and the use of ergotamine with this quiz. Explore guidelines, contraindications, adverse effects, and nursing implications for the administration of ergotamine in the treatment of migraine headaches.

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