12 Questions
Which equation accounts for both the chemical and electrical driving forces that act on an ion?
Nernst equation
What will be the direction of an ion when the membrane potential is at its equilibrium potential?
No net movement
What generates the resting membrane potential?
Differential ion concentrations across the membrane
Which equation is used to understand the basis of membrane potential in reference to ion permeabilities?
Goldman-Hodgkin-Katz equation
What type of conduction is characterized by passive, local, graded potentials?
Electrotonic conduction
Which type of conduction is associated with myelinated axons and is a solution to energy and speed issues?
Salutatory conduction
What accounts for the absolute refractory period during action potential propagation?
Voltage-Gated Sodium Channel
Which mechanism turns different kinds of stimuli into action potentials in the nervous system?
Sensory transduction
What is the consequence of demyelinating diseases on action potential propagation frequency?
It decreases as the disease progresses
What determines the size of a graded potential?
Stimulus strength
What type of potential is responsible for coding intensity in sensory systems?
Receptor potential
Which type of conduction is characterized by a decrease in action potential propagation frequency in demyelinating diseases?
Saltatory conduction
Study Notes
Ion Movement and Membrane Potential
- The Goldman equation accounts for both the chemical and electrical driving forces that act on an ion.
- When the membrane potential is at its equilibrium potential, the direction of an ion is zero, meaning there is no net movement of ions.
Generation of Resting Membrane Potential
- The resting membrane potential is generated by the unequal distribution of ions across the cell membrane.
Ion Permeabilities and Membrane Potential
- The Goldman-Hodgkin-Katz equation is used to understand the basis of membrane potential in reference to ion permeabilities.
Conduction Types
- Electrotonic conduction is characterized by passive, local, graded potentials.
- Saltatory conduction is associated with myelinated axons and is a solution to energy and speed issues.
Action Potential Propagation
- The absolute refractory period during action potential propagation is accounted for by the inactivation of sodium channels.
Mechanisms of Action Potentials
- The transduction mechanism turns different kinds of stimuli into action potentials in the nervous system.
Effects of Demyelination
- Demyelinating diseases result in a decrease in action potential propagation frequency.
- In demyelinating diseases, the consequence is a decrease in action potential propagation frequency.
Graded Potentials
- The size of a graded potential is determined by the strength of the stimulus.
- Graded potentials are responsible for coding intensity in sensory systems.
Test your understanding of equilibrium and membrane potentials in this quiz. Topics covered include defining electrochemical equilibrium, equilibrium potential, and writing the simplified Nernst equation. Prepare to demonstrate your knowledge of internal and external ion concentrations.
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