Eptifibatide - Integrilin Flashcards

Glycoprotein IIb/IIIa inhibitor, platelet aggregation inhibitor

Prevents the aggregation of platelets by binding to the glycoprotein receptor, preventing the binding of fibrinogen and von Willebrand factors

Unstable angina and NSTEMI being managed medically. Patients undergoing percutaneous coronary intervention.

<p>Any prior intracranial hemorrhage, known malignant intracranial neoplasm, suspected aortic dissection, significant closed head trauma or facial trauma within 3 months, active internal bleeding or bleeding disorder in past 30 days, surgical procedure or trauma within preceding 6 weeks</p> Signup and view all the answers

<p>Cerebral hemorrhage, pulmonary hemorrhage, hypotension, GI bleeding, internal bleeding, anaphylactic shock</p> Signup and view all the answers

<p>Thrombolytics, oral anticoagulants, aspirin, NSAIDs, dipyridamole, ticlopidine, and clopidogrel increase effect. Incompatible in the same IV line with furosemide (lasix)</p> Signup and view all the answers

<p>2mg/mL vials and 0.75mg/mL bottles</p> Signup and view all the answers

<p>180mcg/kg bolus over 1-2 mins followed by a 2mcg/kg infusion for 72-96 hours</p> Signup and view all the answers

<p>Not recommended</p> Signup and view all the answers

<p>Onset: minutes, Peak: 30min-4hrs, Duration: platelet function recovers within 4-8 hours of discontinuation</p> Signup and view all the answers