Podcast
Questions and Answers
Where does MicroRNA processing take place?
Where does MicroRNA processing take place?
- In the mitochondria
- In the ribosomes
- In the nucleus (correct)
- In the cytoplasm
What is the primary function of MicroRNAs in gene expression?
What is the primary function of MicroRNAs in gene expression?
- To transcribe DNA into mRNA
- To block the translation of mRNAs into proteins (correct)
- To degrade mRNA
- To translate mRNAs into proteins
What is the approximate length of MicroRNA molecules?
What is the approximate length of MicroRNA molecules?
- Around 22 nucleotides (correct)
- Around 20 nucleotides
- Around 30 nucleotides
- Around 10 nucleotides
At which stage of gene expression can MicroRNAs regulate?
At which stage of gene expression can MicroRNAs regulate?
What is the name of the complex that MicroRNAs are incorporated into?
What is the name of the complex that MicroRNAs are incorporated into?
What is the role of the enzyme in MicroRNA processing?
What is the role of the enzyme in MicroRNA processing?
What is the primary function of RNA processing in gene expression?
What is the primary function of RNA processing in gene expression?
What percentage of human genes are known to undergo alternative splicing?
What percentage of human genes are known to undergo alternative splicing?
What is the outcome of DNA methylation in gene expression?
What is the outcome of DNA methylation in gene expression?
What is the term for the process by which different exons from the same gene are joined in different combinations?
What is the term for the process by which different exons from the same gene are joined in different combinations?
What is the ultimate goal of regulating gene expression?
What is the ultimate goal of regulating gene expression?
What is the step at which alternative splicing occurs?
What is the step at which alternative splicing occurs?
What is the primary function of microRNAs in humans?
What is the primary function of microRNAs in humans?
What is the term for a heritable change in the DNA sequence that is associated with a disease?
What is the term for a heritable change in the DNA sequence that is associated with a disease?
What type of mutation involves the replacement of one nucleotide by another?
What type of mutation involves the replacement of one nucleotide by another?
What is the term for variations in the DNA sequence that do not affect the phenotype?
What is the term for variations in the DNA sequence that do not affect the phenotype?
What is the process by which microRNAs prevent the translation of messenger RNA into protein?
What is the process by which microRNAs prevent the translation of messenger RNA into protein?
What is the term for a change in the DNA sequence that is associated with an abnormal phenotype or disease?
What is the term for a change in the DNA sequence that is associated with an abnormal phenotype or disease?
What is the effect of a haplo-insufficient mutation on protein function?
What is the effect of a haplo-insufficient mutation on protein function?
What is the characteristic of dominant negative effect mutations?
What is the characteristic of dominant negative effect mutations?
What is the result of a mutation that leads to stop gene expression?
What is the result of a mutation that leads to stop gene expression?
What is the effect of a loss of function mutation on protein activity?
What is the effect of a loss of function mutation on protein activity?
What type of mutations can lead to osteogenesis imperfecta?
What type of mutations can lead to osteogenesis imperfecta?
In which type of proteins are dominant negative effect mutations common?
In which type of proteins are dominant negative effect mutations common?
What type of mutation occurs when the number of nucleotides is not a multiple of three?
What type of mutation occurs when the number of nucleotides is not a multiple of three?
What is the effect of a synonymous mutation on the amino acid sequence?
What is the effect of a synonymous mutation on the amino acid sequence?
What is the result of a nonsense mutation?
What is the result of a nonsense mutation?
What type of mutation is a substitution of one nucleotide for another?
What type of mutation is a substitution of one nucleotide for another?
What is the purpose of the notation 'c.131G>A' in describing a mutation?
What is the purpose of the notation 'c.131G>A' in describing a mutation?
What is the difference between a somatic mutation and another type of mutation?
What is the difference between a somatic mutation and another type of mutation?
What is the effect of a gain of function mutation on the normal protein function?
What is the effect of a gain of function mutation on the normal protein function?
What is the result of a RAS mutation that leads to constitutive activation of the cell cycle?
What is the result of a RAS mutation that leads to constitutive activation of the cell cycle?
What is the characteristic of Charcot-Marie-Tooth disease?
What is the characteristic of Charcot-Marie-Tooth disease?
What is the effect of a gain of function mutation on protein production?
What is the effect of a gain of function mutation on protein production?
What is the role of RAS genes in the cell cycle?
What is the role of RAS genes in the cell cycle?
What is the consequence of a gain of function mutation on the paternal allele?
What is the consequence of a gain of function mutation on the paternal allele?
What is the result of a mutation that leads to the locking of RAS protein in its GTP active form?
What is the result of a mutation that leads to the locking of RAS protein in its GTP active form?
What is the effect of a gain of function mutation on the maternal allele?
What is the effect of a gain of function mutation on the maternal allele?
What is the characteristic of RAS mutations in cancer?
What is the characteristic of RAS mutations in cancer?
What is the outcome of a gain of function mutation on protein function?
What is the outcome of a gain of function mutation on protein function?
