Podcast
Questions and Answers
Which of the following is NOT an epigenetic modification mentioned that regulates gene expression in human malignancies?
Which of the following is NOT an epigenetic modification mentioned that regulates gene expression in human malignancies?
What do abnormal metabolism and biochemical pathways, along with mutations in epigenetic actor genes, further demonstrate in cancer pathologies?
What do abnormal metabolism and biochemical pathways, along with mutations in epigenetic actor genes, further demonstrate in cancer pathologies?
Which process involves the reorganization of nucleosomes to regulate gene expression?
Which process involves the reorganization of nucleosomes to regulate gene expression?
In the context of cancer, what is the role of microRNAs as epigenetic modifiers?
In the context of cancer, what is the role of microRNAs as epigenetic modifiers?
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Which epigenetic modification involves the addition of a methyl group to DNA?
Which epigenetic modification involves the addition of a methyl group to DNA?
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Flashcards
Epigenetic modifications
Epigenetic modifications
Changes to gene expression without altering DNA sequence, including methylation and histone modifications.
DNA methylation
DNA methylation
The addition of methyl groups to DNA, affecting gene expression and often silencing genes.
Histone modifications
Histone modifications
Chemical alterations to histone proteins that affect how tightly DNA is wound around them, influencing gene access.
MicroRNAs
MicroRNAs
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Nucleosome remodelling
Nucleosome remodelling
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Study Notes
Epigenetic Modifications in Cancer
- Epigenetic modifications (DNA methylation, histone modifications, microRNAs, and nucleosome remodeling) control gene expression in human cancers.
- Aberrant metabolism and biochemical pathways link genetics and epigenetics in cancer.
- Mutations in genes involved in epigenetic regulation contribute to cancer development.
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Description
This quiz explores the role of epigenetic modifications, including DNA methylation and histone modifications, in cancer development. It examines how these alterations control gene expression and their connections to metabolism and genetic mutations. Test your knowledge on the intricate relationship between genetics and epigenetics in oncology.
