Podcast
Questions and Answers
What is the primary role of the cutaneous plexus in the skin?
What is the primary role of the cutaneous plexus in the skin?
Which tissue types are primarily found in the hypodermis?
Which tissue types are primarily found in the hypodermis?
What change in color of a bruise is primarily due to the degradation of which component?
What change in color of a bruise is primarily due to the degradation of which component?
Which type of hair is referred to as 'lanugo'?
Which type of hair is referred to as 'lanugo'?
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Which of the following functions is NOT regulated by nerve cells in the skin?
Which of the following functions is NOT regulated by nerve cells in the skin?
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What is the primary function of hair in relation to the scalp?
What is the primary function of hair in relation to the scalp?
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How long does the active phase of hair growth typically last?
How long does the active phase of hair growth typically last?
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What happens to hair during the resting phase?
What happens to hair during the resting phase?
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What is the primary role of keratinocytes in the skin?
What is the primary role of keratinocytes in the skin?
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What role does the arrector pili muscle play concerning hair?
What role does the arrector pili muscle play concerning hair?
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Which of the following statements about hair growth cycles is accurate?
Which of the following statements about hair growth cycles is accurate?
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What is the function of hemidesmosomes in the epidermis?
What is the function of hemidesmosomes in the epidermis?
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Which layer of the epidermis is primarily responsible for the formation of epidermal ridges?
Which layer of the epidermis is primarily responsible for the formation of epidermal ridges?
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What differentiates thick skin from thin skin?
What differentiates thick skin from thin skin?
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What is a significant consequence of a larger surface area between the epidermis and dermis?
What is a significant consequence of a larger surface area between the epidermis and dermis?
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What primarily contributes to the pigmentation of the skin?
What primarily contributes to the pigmentation of the skin?
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Why do calluses form on skin?
Why do calluses form on skin?
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What is the role of the stratum corneum in the epidermis?
What is the role of the stratum corneum in the epidermis?
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What is the primary cause of vitiligo?
What is the primary cause of vitiligo?
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Which layer of the dermis contains dense irregular connective tissue and is associated with skin elasticity and strength?
Which layer of the dermis contains dense irregular connective tissue and is associated with skin elasticity and strength?
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How does increased blood flow affect skin color?
How does increased blood flow affect skin color?
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What is the function of calcitriol produced from cholecalciferol?
What is the function of calcitriol produced from cholecalciferol?
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What condition is primarily caused by a deficiency of Vitamin D3 in children?
What condition is primarily caused by a deficiency of Vitamin D3 in children?
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Which statement about the structure of the dermis is correct?
Which statement about the structure of the dermis is correct?
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What happens to skin capillaries during exposure to cold temperatures?
What happens to skin capillaries during exposure to cold temperatures?
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What are lines of cleavage in the context of skin anatomy?
What are lines of cleavage in the context of skin anatomy?
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What type of secretion do sebaceous glands primarily use?
What type of secretion do sebaceous glands primarily use?
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Which of the following components is NOT found in sebum?
Which of the following components is NOT found in sebum?
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How do merocrine sweat glands primarily control their function?
How do merocrine sweat glands primarily control their function?
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What is the function of ceruminous glands in the external ear?
What is the function of ceruminous glands in the external ear?
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What is a key characteristic of apocrine sweat gland secretion?
What is a key characteristic of apocrine sweat gland secretion?
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What mechanism do apocrine sweat glands actually use for secretion?
What mechanism do apocrine sweat glands actually use for secretion?
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What condition can arise from the collection of sebum in sebaceous glands?
What condition can arise from the collection of sebum in sebaceous glands?
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Which of the following functions is NOT associated with the secretion from merocrine sweat glands?
Which of the following functions is NOT associated with the secretion from merocrine sweat glands?
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Study Notes
Epidermis
- Keratinocytes are the main cell type, forming layers in the epidermis.
- Hemidesmosomes connect keratinocytes to the basal lamina.
- New keratinocytes are pushed towards the surface, eventually shedding.
- Epidermal ridges are waves that bind to dermal papillae, increasing surface area for stronger attachment, nutrient exchange, and blood vessel/nerve distribution.
- Thick skin covers palms and soles with 5 layers of keratinocytes.
- Thin skin covers most of the body with 4 layers of keratinocytes.
Epidermis Layers
- Stratum corneum (outermost): 25-30 layers of dead cells.
- Stratum lucidum (palms and soles only): translucent layer.
- Stratum granulosum (grainy): contains granules.
- Stratum spinosum (spiny): contains spine-like projections.
- Stratum germinativum/basale (base): contains stem cells, is anchored to the basal lamina by hemidesmosomes, and forms epidermal ridges.
Epidermis Functions
- Melanin provides skin color and allows for tanning.
- Carotene and oxygen-rich hemoglobin also contribute to skin color.
- Keratin stiffens epidermal tissue, forming fingernails.
Skin Color
- Vitiligo results from loss of melanocytes, causing white patches on the skin.
- Dermal circulation influences skin color.
- Increased blood flow causes a flush due to dilated blood vessels.
- Oxygenated hemoglobin gives a bright red appearance, especially visible in light-skinned individuals.
- Constricted capillaries or reduced blood flow cause paler skin.
- Deoxygenated hemoglobin appears dark red or blue (cyanosis).
Vitamin D3 Production
- Epithelial cells in the stratum spinosum and germinativum produce vitamin D3 (cholecalciferol) in response to sunlight.
- The liver converts cholecalciferol into an intermediate product.
- The kidney converts the intermediate product into calcitriol, a hormone required for calcium absorption from the digestive tract.
Dermis
- Two layers: papillary and reticular.
- Papillary layer: aerolar tissue with folds (dermal papillae) containing capillaries, lymphatics, and sensory neurons.
- Reticular layer: dense irregular connective tissue with a network of collagen and elastic fibers, containing hair follicles, sweat glands, lymphatic vessels, nerve fibers, and contributing to dermal strength and elasticity.
- Lines of cleavage are formed by parallel bundles of collagen and elastin, resisting forces applied to the skin.
- Dermal blood supply is extensive, with networks of arteries and veins between the dermis and hypodermis, supplying nutrients and oxygen to the epidermis.
Bruises
- Occur due to blood vessel damage, releasing hemoglobin.
- Hemoglobin initially appears purple/blue, degrading to yellow/green over time.
Skin Innervation
- Nerve cells regulate blood flow, gland secretion, and sensory receptors.
- Sensory receptors respond to light touch, deep pressure, vibration, chemicals, temperature, and pain.
Hypodermis
- Tissue types: aerolar and adipose tissue.
- Functions: elasticity, heat reduction, energy reserve (lipids), blood reservoir.
Skin Appendages
- Hair follicles, hair, nails, sweat glands, sebacous glands, and ceruminous glands.
- Terminal hair is found on the head.
- Specialized terminal hair includes eyelashes and eyebrows.
- Vellus hair is body hair.
- Lanugo hair is baby hair.
Hair
- Insulates and protects the scalp from damage.
- Protects nostrils and ear canals from debris.
- Detects movement through the hair plexus sensory nerve.
- Arrector pili muscle stands up, causing goosebumps.
Hair Growth Cycle
- Active phase: hair grows continuously (2-5 years).
- Regression phase: follicle transitions to resting phase.
- Resting phase: hair detaches from follicle, becoming a club hair.
- Shedding: club hair is shed, and the hair matrix produces a replacement hair.
Sebaceous Glands
- Secrete oil through holocrine secretion.
-
Two types:
- Simple branched alveolar glands: share duct with hair follicle.
- Sebaceous follicles: not attached to hair follicles.
- Secretions: sebum (lipids + electrolytes + proteins + cholesterol)
- Functions: inhibits bacterial growth due to acidity, lubricates and protects keratinized cells.
Sweat Glands
- Sudoriferous glands.
- Merocrine sweat glands (eccrine sweat glands): coiled tubular ducts using exocytosis, controlled by the thermoregulatory center and emotional centers of the brain.
- Apocrine sweat glands: coiled tubular structures opening into hair follicles, secretions are influenced by hormones.
- Ceruminous glands (modified apocrine sweat glands): located in the external ear, secrete cerumen (ear wax).
Sweat Gland Secretions
- Merocrine sweat glands: watery, used for cooling the skin, excreting water and electrolytes, flushing chemicals, and containing dermicidin (an antibiotic protein).
- Apocrine sweat glands: sticky, cloudy, odorous, and influenced by hormones.
- Ceruminous glands: cerumen (ear wax) traps foreign particles, protecting the ear drum.
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Description
Explore the structure and functions of the epidermis in this quiz. Learn about the key cell types, layers, and unique features of both thick and thin skin. Test your knowledge on how these components contribute to skin health and stability.