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Questions and Answers
Which of the following best describes the purpose of enzymes in biochemical reactions?
Which of the following best describes the purpose of enzymes in biochemical reactions?
Why should pharmacists care about enzymes?
Why should pharmacists care about enzymes?
Which theory explains how enzymes bind to their substrate?
Which theory explains how enzymes bind to their substrate?
What are co-factors and co-enzymes in relation to enzymes?
What are co-factors and co-enzymes in relation to enzymes?
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What is the difference between apo and holo enzymes?
What is the difference between apo and holo enzymes?
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Study Notes
Purpose of Enzymes
- Enzymes are biological catalysts that speed up biochemical reactions without being consumed.
- They lower the activation energy required for reactions to occur, making processes more efficient.
Importance for Pharmacists
- Understanding enzyme function is crucial for drug development and pharmacotherapy.
- Certain medications may interact with enzymes, either inhibiting or enhancing their activity, impacting drug metabolism.
Enzyme Binding Theory
- The Induced Fit Theory explains how enzymes bind to their substrates.
- This theory suggests that enzymes undergo a conformational change upon substrate binding, leading to a more precise fit.
Co-factors and Co-enzymes
- Co-factors are non-protein molecules that assist enzymes by stabilizing their structures or participating in the catalytic process.
- Co-enzymes are a subset of co-factors, organic molecules that transfer chemical groups or electrons during reactions, often derived from vitamins.
Apo and Holo Enzymes
- Apo enzymes are inactive forms of enzymes that lack their co-factors or co-enzymes.
- Holo enzymes are the active forms, consisting of the apo enzyme plus the necessary co-factors or co-enzymes to function properly.
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Description
Test your knowledge on the mechanism of action of enzymes in biochemistry. This quiz covers the fundamentals of enzymes as discussed in Harper's Illustrated Biochemistry Chapter 7. Perfect for students taking Biochem I: Fundamentals in Fall 2023.
