Enzyme Induced by Chronic Alcohol Consumption
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Questions and Answers

Which of the following enzymes is induced by chronic alcohol consumption?

  • Alanine transaminase.
  • Aspartate transaminase.
  • Gamma-Glutamyltransferase. (correct)
  • Alkaline phosphatase.
  • Excess Carbon dioxide (CO2) is found in the following non-compensated conditions

  • Metabolic acidosis.
  • Metabolic alkalosis.
  • Respiratory acidosis. (correct)
  • Respiratory alkalosis.
  • The cell responsible for the formation of a foam cell in an atherosclerotic plaque is ….

  • Macrophage. (correct)
  • Lymphocyte.
  • Neutrophil.
  • Basophil.
  • What disorder can present with hypoketotic hypoglycaemia?

    <p>Medium chain acyl-CoA dehydrogenase deficiency (MCADD).</p> Signup and view all the answers

    The majority of the Thyroid hormones in the blood are bound to proteins. Which of the following is not a thyroid hormone?

    <p>Thyroglobulin</p> Signup and view all the answers

    Which of the following cellular processes increase in the response to thyroid-stimulating hormones?

    <p>All the above</p> Signup and view all the answers

    Which of the following best describes Hashimoto's disease?

    <p>Hyperthyroidism caused by antibodies that destroy thyroid tissue</p> Signup and view all the answers

    Which of the following pattern of thyroid function tests would you expect to see in Graves' disease?

    <p>Low TSH, highT4, high T3, positive for thyroid stimulating antibodies</p> Signup and view all the answers

    Aldosterone is a hormone that increases the renal reabsorption of Nat and increases extracellular fluid and blood volume. Identify the correct statement associated with aldosterone.

    <p>ACTH increases the production of aldosterone</p> Signup and view all the answers

    Which is found in obstructive jaundice?

    <p>High serum conjugated bilirubin.</p> Signup and view all the answers

    Study Notes

    Enzymes and Chronic Alcohol Consumption

    • Chronic alcohol consumption induces the enzyme MEOS (Microsomal Ethanol Oxidizing System)

    Respiratory Acidosis

    • Excess Carbon dioxide (CO2) is found in non-compensated conditions

    Atherosclerosis

    • Foam cells in an atherosclerotic plaque are formed by macrophages

    Metabolic Disorders

    • Hypoketotic hypoglycemia is a characteristic of fatty acid oxidation disorders

    Thyroid Hormones

    • Most thyroid hormones in the blood are bound to proteins (99.97% of T4 and 99.7% of T3)
    • Reverse T3 (rT3) is not a thyroid hormone
    • Thyroid-stimulating hormones increase cellular processes such as glycolysis, gluconeogenesis, and fatty acid oxidation
    • Hashimoto's disease is a chronic autoimmune thyroiditis characterized by hypothyroidism, goiter, and autoantibodies against thyroid peroxidase and thyroglobulin
    • In Graves' disease, thyroid function tests show elevated T4 and T3, and low TSH levels

    Aldosterone and Renal Function

    • Aldosterone increases renal reabsorption of sodium (Nat), leading to increased extracellular fluid and blood volume
    • Aldosterone stimulates the kidney to secrete potassium in exchange for sodium reabsorption

    Jaundice

    • Bilirubin is found in obstructive jaundice

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    Description

    This quiz tests your knowledge of the enzyme that is induced as a result of chronic alcohol consumption. Identify the correct enzyme from the options provided. This is an important concept in biochemistry and pharmacology.

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