Alcohol Metabolism and Hepatic Toxicity Quiz

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What is the purpose of including PT in the tests for liver disease?

To assess liver fibrosis
To measure nitrogen metabolism
To aid in the diagnosis of liver disease
To determine the risk of bleeding (correct)

What condition is Ig A elevated in?

Alcoholic cirrhosis (correct)
Metastatic carcinoma of the liver
Chronic active hepatitis
Primary biliary cirrhosis

In liver failure, what happens to the levels of ammonia?

They are converted to urea by the liver
They decrease in the bloodstream
They increase in the bloodstream (correct)
They are not toxic to the body

Which test may reveal high serum levels in metastatic carcinoma of the liver?

Lactate dehydrogenase (D) Signup and view all the answers

What method is preferred for analyzing serum bilirubin according to the text?

Evelyn and Malloy method (D) Signup and view all the answers

Why should a fasting sample be used when processing bilirubin?

To prevent falsely elevated bilirubin concentration (D) Signup and view all the answers

What can happen if a hemolyzed sample is used for bilirubin analysis?

Decreased reaction with diazotized sulfanilic acid (D) Signup and view all the answers

How is urobilinogen measured in feces according to the text?

Treatment with alkaline ferrous hydroxide before Ehrlich’s reagent is added (D) Signup and view all the answers

Which of the following is NOT true about the Jendrassik and Grof method for bilirubinometry?

It is less sensitive than the Evelyn and Malloy method. (B) Signup and view all the answers

Which of the following statements is true regarding bilirubinometry in neonatal population using POCT?

It uses wavelengths that provide a numerical index based on skin reflection. (D) Signup and view all the answers

In the Van Den Burgh method for bilirubin quantitation, when can the diazo reaction be applied to serum samples?

Only in the presence of an accelerator. (D) Signup and view all the answers

Which of the following is accurate about the Evelyn and Malloy method for bilirubin quantitation?

The accelerator used includes 50% methanol as a solubilizer. (A) Signup and view all the answers

Why is unprotected light exposure an issue in bilirubin values measurement?

It could make bilirubin values appear falsely normal. (A) Signup and view all the answers

Which method is described as being more sensitive than the Evelyn and Malloy method for bilirubin quantitation?

Jendrassik and Grof method (B) Signup and view all the answers

What is the role of caffeine sodium benzoate in the Jendrassik and Grof method for bilirubin quantitation?

It serves as an accelerator. (A) Signup and view all the answers

What can be inferred about urine urobilinogen levels when absent from both urine and stool?

Suggests complete biliary obstruction (C) Signup and view all the answers

What is true about the use of distilled water as blanks in bilirubin quantitation?

Specific blanks are used to eliminate interferences (D) Signup and view all the answers

What outcome can occur if serum samples are not properly stored before bilirubin quantitation?

Decrease in bilirubin values over time (D) Signup and view all the answers

Which characteristic is associated with bilirubin quantitation using Van Den Burgh method?

Utilizes 0.1% Sulfanilic Acid + HCl for diazo A (D) Signup and view all the answers