Alcohol Metabolism and Hepatic Toxicity Quiz

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19 Questions

What is the purpose of including PT in the tests for liver disease?

To determine the risk of bleeding

What condition is Ig A elevated in?

Alcoholic cirrhosis

In liver failure, what happens to the levels of ammonia?

They increase in the bloodstream

Which test may reveal high serum levels in metastatic carcinoma of the liver?

Lactate dehydrogenase

What method is preferred for analyzing serum bilirubin according to the text?

Evelyn and Malloy method

Why should a fasting sample be used when processing bilirubin?

To prevent falsely elevated bilirubin concentration

What can happen if a hemolyzed sample is used for bilirubin analysis?

Decreased reaction with diazotized sulfanilic acid

How is urobilinogen measured in feces according to the text?

Treatment with alkaline ferrous hydroxide before Ehrlich’s reagent is added

Which of the following is NOT true about the Jendrassik and Grof method for bilirubinometry?

It is less sensitive than the Evelyn and Malloy method.

Which of the following statements is true regarding bilirubinometry in neonatal population using POCT?

It uses wavelengths that provide a numerical index based on skin reflection.

In the Van Den Burgh method for bilirubin quantitation, when can the diazo reaction be applied to serum samples?

Only in the presence of an accelerator.

Which of the following is accurate about the Evelyn and Malloy method for bilirubin quantitation?

The accelerator used includes 50% methanol as a solubilizer.

Why is unprotected light exposure an issue in bilirubin values measurement?

It could make bilirubin values appear falsely normal.

Which method is described as being more sensitive than the Evelyn and Malloy method for bilirubin quantitation?

Jendrassik and Grof method

What is the role of caffeine sodium benzoate in the Jendrassik and Grof method for bilirubin quantitation?

It serves as an accelerator.

What can be inferred about urine urobilinogen levels when absent from both urine and stool?

Suggests complete biliary obstruction

What is true about the use of distilled water as blanks in bilirubin quantitation?

Specific blanks are used to eliminate interferences

What outcome can occur if serum samples are not properly stored before bilirubin quantitation?

Decrease in bilirubin values over time

Which characteristic is associated with bilirubin quantitation using Van Den Burgh method?

Utilizes 0.1% Sulfanilic Acid + HCl for diazo A

Test your knowledge on alcohol metabolism and the hepatic toxicity caused by ethanol. Learn about the enzymes involved in alcohol metabolism, such as alcohol dehydrogenase and aldehyde dehydrogenase, and the breakdown process from alcohol to water and carbon dioxide.

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