Enteric Nervous System Overview
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Questions and Answers

What segments of the spinal cord do the sacral parasympathetics originate from?

  • C1, C2, C3
  • L1, L2, L3
  • S2, S3, S4 (correct)
  • T1, T2, T3
  • Which of the following statements about sympathetic stimulation of the gastrointestinal tract is true?

  • It exclusively innervates the large intestine.
  • It has no effect on intestinal secretion.
  • It promotes increased gastrointestinal motility.
  • It inhibits gastrointestinal tract activity. (correct)
  • Where do most of the postganglionic sympathetic neuron bodies for the gastrointestinal tract reside?

  • Celiac and mesenteric ganglia (correct)
  • Spinal cord
  • Dorsal root ganglia
  • Sacral ganglia
  • Which neurotransmitter is mainly associated with sympathetic nerve endings in the gastrointestinal tract?

    <p>Norepinephrine</p> Signup and view all the answers

    What primarily initiates intestinal peristalsis?

    <p>Distention of the gut</p> Signup and view all the answers

    What role does the myenteric plexus play in peristalsis?

    <p>It is required for effective peristalsis</p> Signup and view all the answers

    What type of fibers supply the sigmoidal, rectal, and anal regions with better parasympathetic supply compared to other intestinal areas?

    <p>Parasympathetic fibers</p> Signup and view all the answers

    Which of the following can inhibit peristalsis?

    <p>Administration of atropine</p> Signup and view all the answers

    Which of the following is NOT a stimulus for the afferent sensory nerve fibers from the gut?

    <p>Nutrient absorption</p> Signup and view all the answers

    Which of the following statements about mixing movements in the gastrointestinal tract is true?

    <p>Peristaltic contractions can cause mixing when forward progression is blocked</p> Signup and view all the answers

    Which segments of the spinal cord are involved in sympathetic innervation of the gastrointestinal tract?

    <p>T5 to L2</p> Signup and view all the answers

    What type of contractions primarily aid in the mixing of contents within the gut wall?

    <p>Local intermittent constrictive contractions</p> Signup and view all the answers

    What effect do signals transmitted through afferent sensory nerve fibers typically have on intestinal activities?

    <p>Cause excitation or inhibition of intestinal movements</p> Signup and view all the answers

    What happens when there is a congenital absence of the myenteric plexus?

    <p>Peristalsis occurs weakly or not at all</p> Signup and view all the answers

    What stimulus other than gut distention can initiate peristalsis?

    <p>Chemical or physical irritation of the epithelial lining</p> Signup and view all the answers

    What effect does strong parasympathetic nervous signaling have on the gut?

    <p>It promotes strong peristalsis</p> Signup and view all the answers

    What is the primary trigger for the secretion of gastric inhibitory peptide?

    <p>Fatty acids and amino acids</p> Signup and view all the answers

    What is the main function of motilin in the gastrointestinal tract?

    <p>Increase gastrointestinal motility</p> Signup and view all the answers

    Which movement type primarily facilitates the forward movement of food in the gastrointestinal tract?

    <p>Propulsive movements</p> Signup and view all the answers

    How often do the interdigestive myoelectric complexes occur in a fasting person?

    <p>Every 90 minutes</p> Signup and view all the answers

    What explains the mechanism by which peristalsis occurs in the gastrointestinal tract?

    <p>The presence of a contractile ring that spreads along the gut</p> Signup and view all the answers

    What happens to motilin secretion after food ingestion?

    <p>It experiences a partial decrease</p> Signup and view all the answers

    Which of the following is NOT a functional type of movement in the gastrointestinal tract?

    <p>Reflexive sliding</p> Signup and view all the answers

    What role do mixing movements play in the gastrointestinal tract?

    <p>They keep intestinal contents thoroughly mixed</p> Signup and view all the answers

    What is the primary role of the myenteric plexus in the enteric nervous system?

    <p>Controlling gastrointestinal movements</p> Signup and view all the answers

    How many neurons approximately compose the enteric nervous system?

    <p>100 million</p> Signup and view all the answers

    What is the main function of the submucosal plexus?

    <p>Regulating local blood flow and secretion</p> Signup and view all the answers

    Which type of fibers enhance or inhibit gastrointestinal functions through the enteric nervous system?

    <p>Extrinsic sympathetic and parasympathetic fibers</p> Signup and view all the answers

    Where do sensory nerve endings in the gastrointestinal tract send their afferent fibers?

    <p>To both the enteric plexuses and the spinal cord</p> Signup and view all the answers

    What anatomical feature does the myenteric plexus lie between?

    <p>Longitudinal and circular muscle layers</p> Signup and view all the answers

    What is the potential effect of the enteric nervous system functioning independently of extrinsic nerves?

    <p>Regulation of gastrointestinal functions without external input</p> Signup and view all the answers

    Which statement correctly describes the relationship between the enteric nervous system and extrinsic nerves?

    <p>Stimulation by extrinsic nerves can modify enteric functions</p> Signup and view all the answers

    What is the primary role of the myenteric plexus in the gastrointestinal tract?

    <p>To control muscle activity along the length of the gut</p> Signup and view all the answers

    Which of the following effects is NOT associated with the stimulation of the myenteric plexus?

    <p>Increased calcium absorption in the intestines</p> Signup and view all the answers

    What type of neurotransmitter is released by some inhibitory neurons within the myenteric plexus?

    <p>Vasoactive intestinal polypeptide</p> Signup and view all the answers

    The submucosal plexus is primarily concerned with which of the following functions?

    <p>Managing the secretion of digestive enzymes and blood flow within the intestinal wall</p> Signup and view all the answers

    Which muscle layer does the myenteric plexus lie between in the gastrointestinal tract?

    <p>Longitudinal and circular layers</p> Signup and view all the answers

    The myenteric plexus is involved in which of the following processes?

    <p>Facilitating rapid gut peristaltic waves</p> Signup and view all the answers

    What is the effect of inhibitory signals from the myenteric plexus on intestinal sphincter muscles?

    <p>They facilitate the flow of food by reducing resistance</p> Signup and view all the answers

    How does the myenteric plexus affect the tone of the gut wall when stimulated?

    <p>It increases the tonic contraction of the gut wall</p> Signup and view all the answers

    Study Notes

    Enteric Nervous System Overview

    • The enteric nervous system extends from the esophagus to the anus, containing approximately 100 million neurons, comparable to the entire spinal cord.
    • Comprised of two main plexuses:
      • Myenteric Plexus (Auerbach’s Plexus): Located between longitudinal and circular muscle layers, primarily controls gastrointestinal movements.
      • Submucosal Plexus (Meissner’s Plexus): Positioned in the submucosa, mainly regulates secretion and local blood flow.

    Functional Roles of Plexuses

    • Myenteric Plexus:
      • Increases gut wall tone, rhythmical contractions, and conduction velocity of excitatory waves.
      • Contains excitatory and inhibitory neurons; inhibitory signals help relax intestinal sphincters.
    • Submucosal Plexus:
      • Regulates function within minute segments of the intestine, involved mainly in local activities like secretion.

    Nervous System Interactions

    • Extrinsic sympathetic and parasympathetic fibers connect to both plexuses, enhancing or inhibiting gastrointestinal activity.
    • Afferent sensory nerve fibers send signals to the enteric system and higher centers (e.g., spinal cord, brain stem), contributing to local reflexes and overall gut reflex actions.

    Sympathetic and Parasympathetic Functions

    • Parasympathetic Fibers: Originate from sacral spinal segments, particularly abundant in the rectal area, involved in defecation reflexes.
    • Sympathetic Fibers: Originate from the spinal cord (T5-L2) and inhibit gastrointestinal activity, with norepinephrine as the primary neurotransmitter.

    Sensory Nerve Functionality

    • Sensory nerve fibers respond to gut mucosa irritation, excessive distention, and certain chemicals, leading to excitation/inhibition of intestinal activity.

    Hormonal Influences

    • Gastric Inhibitory Peptide: Secreted from the upper small intestine in response to fats and amino acids, slows gastric emptying if the intestine is overloaded.
    • Motilin: Released from the upper duodenum during fasting, stimulates gastrointestinal motility with cyclic release every 90 minutes.

    Types of Gut Movements

    • Two primary movement types:
      • Propulsive Movements: Move food through the tract (e.g., peristalsis).
      • Mixing Movements: Ensure thorough mixing of intestinal contents.

    Peristalsis Mechanism

    • Involves a contractile ring that moves forward, moving material ahead. Triggered by gut distention and can be influenced by chemical and physical stimuli.
    • Requires a functional myenteric plexus; absence severely depresses peristalsis.

    Mixing Movements Characteristics

    • Vary across the gastrointestinal tract; peristaltic contractions may cause mixing when forward movement is obstructed.
    • Local constrictive contractions chop and shear contents, enhancing digestion and absorption efficiency.

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    GIT Physiology Lect.1 PDF

    Description

    Explore the complexities of the enteric nervous system, which plays a crucial role in the gastrointestinal tract. This quiz will cover its structure, neurons, and primary functions from the esophagus to the anus. Test your knowledge on this vital aspect of human physiology.

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