Energy and Enzymes Overview

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Questions and Answers

What is the definition of energy?

  • A form of kinetic motion.
  • The ability to do work. (correct)
  • The potential for objects to be still.
  • The capacity to produce heat only.

What happens to potential energy as a wrecking ball falls?

  • It stays constant throughout the fall.
  • It converts entirely into thermal energy.
  • It increases at the same rate as kinetic energy.
  • It decreases as kinetic energy increases. (correct)

Which of the following best describes kinetic energy?

  • Energy associated with an object in motion. (correct)
  • Energy that cannot be transformed to another form.
  • Energy stored in an object based on its position.
  • Energy contained within chemical bonds.

How is potential energy related to work?

<p>It indicates the ability of an object to do work when it moves. (C)</p> Signup and view all the answers

Which of these energy forms will include the potential energy of a wrecking ball?

<p>When the ball is lifted and held stationary in the air. (B)</p> Signup and view all the answers

Which statement about kinetic energy is correct?

<p>Kinetic energy can be observed in any moving object. (C)</p> Signup and view all the answers

What is a proper example of potential energy?

<p>A bullet in a gun before it is fired. (B)</p> Signup and view all the answers

What are the four main ways enzymes catalyze reactions?

<p>Bringing substrates together, compromising bond structures, optimal conditions, forming covalent bonds (B)</p> Signup and view all the answers

What type of energy conversion occurs when a wrecking ball drops?

<p>Potential energy is converted to kinetic energy. (C)</p> Signup and view all the answers

Which of the following statements about enzymes is not true?

<p>They increase ∆G of reactions. (D)</p> Signup and view all the answers

How can enzymes be regulated within a cell?

<p>By temperature and pH, location within the cell, and interaction with other molecules (A)</p> Signup and view all the answers

Which scenario represents a low entropy state?

<p>The instant that a perfume bottle is sprayed. (B)</p> Signup and view all the answers

What does an allosteric inhibitor do to an enzyme?

<p>Binds to an enzyme away from the active site and changes the conformation of the active site, decreasing its affinity for the substrate. (B)</p> Signup and view all the answers

What type of enzyme inhibition involves an inhibitor binding to a site other than the active site?

<p>Noncompetitive inhibition (D)</p> Signup and view all the answers

What is the energy released by the hydrolysis of ATP primarily stored between?

<p>Beta and gamma phosphates. (B)</p> Signup and view all the answers

What is the primary mechanism by which cells regulate metabolic pathways?

<p>Regulation through feedback inhibition where metabolic products act as inhibitors (C)</p> Signup and view all the answers

Which analogy best illustrates the induced-fit model of enzyme-substrate binding?

<p>A hug between two people. (C)</p> Signup and view all the answers

What does feedback inhibition typically involve?

<p>Pathway products acting as inhibitors of enzymes in the pathway (D)</p> Signup and view all the answers

Which of the following accurately describes allosteric regulation?

<p>Activators can enhance enzyme function and inhibitors can prevent function, both involving conformational changes (C)</p> Signup and view all the answers

Which of the following is not an example of energy transformation?

<p>Broken glass falling to the ground. (A)</p> Signup and view all the answers

In the context of entropy, when comparing a brand new car to an old 1950s car, what state of entropy is represented?

<p>High entropy state. (C)</p> Signup and view all the answers

What is the effect of temperature on enzyme activity?

<p>Enzymes can be denatured by excessive heat, reducing activity (A)</p> Signup and view all the answers

What is the correct value for the energy released by the hydrolysis of ATP?

<p>Equal to −57 kcal/mol. (B)</p> Signup and view all the answers

What is the role of activation energy in metabolism?

<p>It is required for reactions to proceed even with enzymatic catalysis (C)</p> Signup and view all the answers

What is the primary function of enzymes in metabolic pathways?

<p>To lower the activation energy of chemical reactions (A)</p> Signup and view all the answers

What is an enzyme's active site?

<p>The region where substrates bind and reactions occur (A)</p> Signup and view all the answers

Which statement about enzymes is true?

<p>Most enzymes are proteins that catalyze biochemical reactions (C)</p> Signup and view all the answers

What happens to the substrates during an enzyme-catalyzed reaction?

<p>They are converted into products through modification (B)</p> Signup and view all the answers

Enzymes do not alter which of the following aspects of a chemical reaction?

<p>The reaction's overall free energy change (A)</p> Signup and view all the answers

How do enzymes affect the transition state of a reaction?

<p>They stabilize the transition state, facilitating the reaction (A)</p> Signup and view all the answers

When two substrates react in the presence of an enzyme, what is most likely to occur?

<p>They form a single product that is released (C)</p> Signup and view all the answers

What are the primary components that make up enzymes?

<p>Amino acid chains forming proteins (A)</p> Signup and view all the answers

What type of process is DNA replication classified as?

<p>Metabolic and anabolic (A)</p> Signup and view all the answers

Which comparison between endergonic and exergonic reactions is accurate?

<p>Both types require activation energy (C)</p> Signup and view all the answers

In the context of metabolism, glucose is primarily considered as what type of molecule compared to ATP?

<p>Catabolic molecule compared to an anabolic molecule (A)</p> Signup and view all the answers

How is the energy associated with a swinging pendulum categorized at its maximum height?

<p>Potential energy only (C)</p> Signup and view all the answers

Which of the following statements regarding reaction rates between two chemical reactions is true?

<p>They can be compared by evaluating their ∆G values (D)</p> Signup and view all the answers

Which option describes the energy states of a pendulum at different points during its swing?

<p>Potential energy increases as it descends (C)</p> Signup and view all the answers

During which phase of DNA replication are complementary strands synthesized?

<p>During the entire process from unwinding to winding (B)</p> Signup and view all the answers

What incorrectly characterizes a catabolic reaction?

<p>Catabolic reactions produce larger molecules from smaller units (B)</p> Signup and view all the answers

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Study Notes

Energy

  • Energy is the ability to do work.
  • There are many forms of energy including electrical, light, heat, kinetic, and potential.

Energy Types

  • Kinetic Energy: Energy associated with objects in motion.
    • Examples: A speeding bullet, rapid molecule movement in the air (heat), light.
  • Potential Energy: Energy associated with the potential to do work.
    • Example: A wrecking ball suspended in the air.

Free Energy

  • Free Energy (G): Energy that is available to do work.
  • Endergonic Reactions: Reactions that require free energy.
    • Have a positive change in free energy (ΔG > 0).
  • Exergonic Reactions: Reactions that release free energy.
    • Have a negative change in free energy (ΔG < 0).

Activation Energy

  • Activation Energy: The amount of energy required to start a chemical reaction.
  • Enzymes lower the activation energy of reactions, but do not change the change in free energy (ΔG).

Enzymes

  • Enzymes: Biological catalysts that speed up chemical reactions.
  • Almost all enzymes are proteins.
  • Enzymes work by binding to the reactant molecules (substrates) at their active site.
  • This binding lowers the activation energy, making the reaction occur more readily.
  • Enzymes do not change the change in free energy (ΔG).
  • Enzyme Regulation:
    • Temperature and pH: Enzymes have optimal temperature and pH ranges. Outside of these ranges, activity decreases.
    • Location: Some enzymes are located in specific cellular compartments, limiting their activity.
    • Inhibition:
      • Competitive Inhibitors: Bind to the active site, blocking substrate binding.
      • Noncompetitive Inhibitors: Bind to a site away from the active site, changing the shape of the active site, decreasing its affinity for the substrate.
    • Activation: Activators can bind to enzymes and enhance their activity.

Feedback Inhibition

  • A common regulatory mechanism in metabolic pathways.
  • Products of a metabolic pathway serve as inhibitors of the enzymes involved in the pathway.
    • This is usually allosteric, meaning the inhibitor binds to a site away from the active site.
    • The inhibitor often acts on the first committed enzyme of the pathway, slowing down the production of the product.

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