Endometriosis Theories
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Questions and Answers

What is the main focus of the Meyer theory regarding the development of endometriosis?

  • Coelomic metaplasia of multipotential cells in the peritoneal cavity (correct)
  • Development of endometriosis after the onset of menstruation
  • Immunologic factors leading to endometriosis
  • Endometrial cell implantation during menstruation

According to the Sampson theory, what is the common explanation for the development of pelvic endometriosis and its predilection for certain sites?

  • Immunologic factors leading to endometriosis
  • Direct implantation of endometrial cells through retrograde menstruation (correct)
  • Development of endometriosis after the onset of menstruation
  • Coelomic metaplasia of multipotential cells in the peritoneal cavity

What characteristic distinguishes pelvic endometriosis according to the Sampson theory?

  • Development after the onset of menstruation
  • Implantation in the pelvic and ovaries (correct)
  • Presence of immunologic factors
  • Occurrence in abdominal incisions or scars

In which scenario would remnant endometrial glands most likely deposit and lead to endometriosis according to the Sampson theory?

<p>Accidental fistula connecting the uterus to the abdominal wall in a patient with a C-section (D)</p> Signup and view all the answers

What is the classic sign of uterosacral nodularity in ovarian endometriomas?

<p>Chocolate cyst (C)</p> Signup and view all the answers

In patients with dyspareunia, what differential diagnoses should be considered?

<p>Chronic pelvic inflammatory disease, ovarian cysts, and symptomatic uterine retroversion (D)</p> Signup and view all the answers

What may cause sudden abdominal pain in addition to a ruptured endometrioma?

<p>Ectopic pregnancy and acute pelvic inflammatory disease (D)</p> Signup and view all the answers

What may the uterus be relatively fixed and retroflexed in the pelvis due to?

<p>Extensive adhesions (D)</p> Signup and view all the answers

What is the purpose of add-back therapy in the context of GnRH agonist treatment?

<p>To counteract the hypoestrogenic effect and mitigate the vasomotor and bone density side effects (C)</p> Signup and view all the answers

When might Norethindrone acetate 5 mg be required for a patient undergoing GnRH agonist therapy?

<p>If a patient develops side effects while taking a GnRH agonist, if the therapy is required for longer than 6 months, or if repeated treatments are required (B)</p> Signup and view all the answers

What is the primary function of GnRH agonists and antagonists in the context of endometriosis treatment?

<p>To block the production of ovarian-stimulating hormones, lowering estrogen levels and preventing menstruation (B)</p> Signup and view all the answers

Why is add-back therapy often started with GnRH agonist therapy?

<p>Because it does not affect the drug's control of pelvic pain (D)</p> Signup and view all the answers

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