Endomembrane System and Bulk Transport Processes

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Questions and Answers

Which of the following is NOT a component of the endomembrane system?

  • Lysosomes
  • Golgi apparatus
  • Mitochondria (correct)
  • Endoplasmic reticulum

What is the primary mechanism by which the endomembrane system is interconnected?

  • By a continuous lipid bilayer
  • Through shared enzymatic reactions
  • Through a network of protein filaments
  • Via direct physical contact or transfer by vesicles (correct)

Where does the synthesis of cytoplasmic proteins primarily occur?

  • Golgi apparatus
  • Free ribosomes (correct)
  • Smooth endoplasmic reticulum (sER)
  • Rough endoplasmic reticulum (rER)

Which of the following is a primary function of the smooth endoplasmic reticulum (sER)?

<p>Lipid synthesis and detoxification (B)</p> Signup and view all the answers

What is the role of the rough endoplasmic reticulum (rER) in protein processing?

<p>Folding and modification of secreted and membrane-bound proteins (C)</p> Signup and view all the answers

What determines the directionality of the Golgi apparatus?

<p>Its inherent polarity, with <em>cis</em> and <em>trans</em> faces (D)</p> Signup and view all the answers

How does the Golgi complex sort proteins for their final destinations?

<p>By adding molecular markers to direct proteins to correct vesicles (B)</p> Signup and view all the answers

What is glycosylation in the context of Golgi complex function?

<p>The addition of carbohydrate groups to proteins (A)</p> Signup and view all the answers

What is the purpose of 'tagging' vesicles leaving the Golgi complex?

<p>To direct them to the correct cellular targets (C)</p> Signup and view all the answers

How do lysosomes contribute to the cell's functionality?

<p>By degrading cellular waste and recycling materials (D)</p> Signup and view all the answers

Why is the internal environment of a lysosome maintained at an acidic pH?

<p>To provide optimal conditions for the activity of hydrolytic enzymes (A)</p> Signup and view all the answers

What is a key function of vacuoles in plant cells?

<p>Storing water and maintaining cell turgor (D)</p> Signup and view all the answers

Which process describes the bulk transport of materials out of the cell?

<p>Exocytosis (C)</p> Signup and view all the answers

What distinguishes constitutive exocytosis from regulated exocytosis?

<p>Constitutive exocytosis is a continuous process, while regulated exocytosis requires a specific signal. (A)</p> Signup and view all the answers

What is the main purpose of endocytosis?

<p>To take up molecules and particulate matter into the cell (D)</p> Signup and view all the answers

Which type of endocytosis is described as 'cell eating'?

<p>Phagocytosis (D)</p> Signup and view all the answers

What is the primary distinction between pinocytosis and receptor-mediated endocytosis?

<p>Pinocytosis is non-selective, while receptor-mediated endocytosis is highly selective. (C)</p> Signup and view all the answers

Which of the following is an example of receptor-mediated endocytosis?

<p>The selective uptake of LDL cholesterol by cells (B)</p> Signup and view all the answers

Which of the following represents the correct order of events in protein secretion from a cell?

<p>ER → Golgi → Plasma membrane (D)</p> Signup and view all the answers

If a cell were unable to perform glycosylation, which cellular process would be MOST directly affected?

<p>Protein sorting and targeting (C)</p> Signup and view all the answers

A cell that specializes in detoxifying drugs and poisons would likely have a large amount of which organelle?

<p>Smooth endoplasmic reticulum (C)</p> Signup and view all the answers

Which defect in lysosomal enzymes would cause lysosomal storage diseases?

<p>Enzymes unable to function properly (B)</p> Signup and view all the answers

A protein is synthesized in the rER, modified in the Golgi, and then needs to be transported to the lysosome. What molecular marker needs to be added?

<p>Mannose-6-phosphate (C)</p> Signup and view all the answers

A researcher is studying a cell line and observes that the cells are secreting large amounts of extracellular matrix proteins. Which process is most likely responsible for this secretion?

<p>Constitutive exocytosis (C)</p> Signup and view all the answers

What is the primary role of hydrolytic enzymes found in lysosomes?

<p>Breaking down macromolecules (D)</p> Signup and view all the answers

During autophagy, which organelle plays a key role in digesting and recycling damaged cellular components?

<p>Lysosome (B)</p> Signup and view all the answers

How do vesicles know where to go after leaving the Golgi?

<p>They have molecular tags that bind to specific receptors (A)</p> Signup and view all the answers

Which of the following is the first step in receptor-mediated endocytosis?

<p>Receptor proteins capture the required solute (D)</p> Signup and view all the answers

Which vesicular transport mechanism is MOST directly involved in the secretion of hormones from endocrine cells?

<p>Regulated exocytosis (C)</p> Signup and view all the answers

If a cell has a mutation that prevents it from properly sorting proteins in the Golgi, what is the MOST likely consequence?

<p>Proteins will be missorted and end up in the wrong cellular locations (D)</p> Signup and view all the answers

A cell internalizes a large bacterium through what process?

<p>Phagocytosis (C)</p> Signup and view all the answers

What would happen if lysosomes lost their acidity?

<p>Hydrolytic enzymes would not function properly (C)</p> Signup and view all the answers

What cellular function is the endomembrane system NOT involved in?

<p>Energy production (B)</p> Signup and view all the answers

Flashcards

Endomembrane System

A system of interconnected organelles (nuclear envelope, ER, Golgi, lysosomes, vacuoles, plasma membrane) in eukaryotic cells.

Protein Synthesis

The synthesis of proteins.

Ribosome

An organelle involved in protein synthesis; gives the rough ER its texture..

Transport Vesicles

Membrane-bound sacs that transport proteins.

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Golgi Apparatus

Cellular organelle that modifies, sorts, and packages proteins.

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Cis Face

The side closet to the ER that recieves vesicles.

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Trans Face

The side of the Golgi where processed vesicles leave.

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Glycosylation

Addition/modification of carbohydrates to proteins.

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Protein Sorting

Adding markers to direct proteins to vesicles.

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Vesicle Trafficking

Directing vesicles to correct cell targets.

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Vesicles

Lipid bilayer, cytoplasm/fluid filled organelles.

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Exocytosis

Transports material out of the cell.

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Constitutive Exocytosis

Releases extracellular matrix proteins.

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Regulated Exocytosis

Releases hormones and neurotransmitters.

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Endocytosis

The cell takes in large molecules.

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Phagocytosis

Cell "eating".

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Pinocytosis

Cell "drinking".

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Receptor-Mediated Endocytosis

Uptake of specific substances.

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Lysosomes

Organelles made by rER/Golgi with hydrolytic enzymes.

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Lysosome Function

Digest and recycle unwanted material.

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Autophagy

Important for cell health.

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Vacuoles

Vesicles derived from the rER and Golgi

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Endoplasmic Reticulum (ER)

Network of membranes involved in protein and lipid synthesis.

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Rough Endoplasmic Reticulum (rER)

ER with ribosomes; involved in protein synthesis.

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Smooth Endoplasmic Reticulum (sER)

ER without ribosomes; involved in lipid synthesis and other functions.

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Metabolism of carbohydrates

Synthesis of carbohydrates.

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Lipid synthesis

Synthesis of lipids.

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Detoxification

Removal of drugs and poisons.

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Calcium ion storage

Storage of ions for signaling.

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