Endocrinology Overview

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Questions and Answers

What is cholesterol primarily a precursor to?

  • Mineral hormones
  • Protein hormones
  • Carbohydrates
  • Steroid hormones (correct)

Which mechanism of hormone release is stimulated by the levels of ions or nutrients in the blood?

  • Humoral mechanism (correct)
  • Neural mechanism
  • Digestive mechanism
  • Hormonal mechanism

Which hormone is an example of a neural mechanism of hormone release?

  • Estrogen
  • Cortisol
  • Insulin
  • Oxytocin (correct)

What does the neuroendocrine system help regulate?

<p>Reproduction and metabolism (B)</p> Signup and view all the answers

What type of hormones are secreted by neurons in the hypothalamus that influence the anterior pituitary gland?

<p>Releasing and inhibiting hormones (B)</p> Signup and view all the answers

What is the primary role of sebaceous glands in the skin?

<p>To secrete oil that lubricates and protects the skin (D)</p> Signup and view all the answers

Which gland is responsible for producing hormones that regulate body functions?

<p>Adrenal glands (C)</p> Signup and view all the answers

What is the function of the pancreas in the digestive system?

<p>To release digestive enzymes and hormones for digestion and blood sugar regulation (A)</p> Signup and view all the answers

Which hormones are primarily produced by the ovaries?

<p>Estrogen and progesterone (D)</p> Signup and view all the answers

What is the primary role of sweat glands in the skin?

<p>To release sweat for thermoregulation (A)</p> Signup and view all the answers

What are the functions of the hypothalamus?

<p>Controls body temperature, hunger, and sleep (A)</p> Signup and view all the answers

Which system connects the hypothalamus to the anterior pituitary?

<p>Hypothalamic-Hypophysial Portal System (HHPS) (D)</p> Signup and view all the answers

What types of hormones does the hypothalamus synthesize and release?

<p>Neurohormones and hypophysiotropic hormones (A)</p> Signup and view all the answers

Which of the following hormones is classified as a neurohormone released by the posterior pituitary?

<p>Oxytocin (B)</p> Signup and view all the answers

Which of these axes is not part of the hypothalamic-pituitary axis?

<p>Hypothalamic-Pituitary-Cardiac (HPC) axis (D)</p> Signup and view all the answers

What is the primary function of endocrine glands?

<p>Secrete hormones directly into the bloodstream (C)</p> Signup and view all the answers

Which of the following substances is secreted by the pancreas as an endocrine hormone?

<p>Insulin (B)</p> Signup and view all the answers

What distinguishes exocrine glands from endocrine glands?

<p>Exocrine glands use ducts to release substances. (A)</p> Signup and view all the answers

Which gland is primarily responsible for regulating growth and metabolism?

<p>Pituitary gland (C)</p> Signup and view all the answers

Which enzyme is NOT produced by the exocrine glands of the pancreas?

<p>Insulin (B)</p> Signup and view all the answers

How is the endocrine system primarily evaluated?

<p>By measuring hormone concentrations (D)</p> Signup and view all the answers

What role do exocrine glands play in the body?

<p>Secretion of substances into an organ or onto the body surface (B)</p> Signup and view all the answers

Which of the following pairs an endocrine gland with its hormone?

<p>Pancreas - Glucagon (D)</p> Signup and view all the answers

Which hormone is responsible for stimulating the release of Adrenocorticotrophic hormone (ACTH)?

<p>Corticotropin-Releasing Hormone (CRH) (C)</p> Signup and view all the answers

What is the role of Dopamine in the hypothalamic system?

<p>Inhibits the secretion of Prolactin (PRL) (B)</p> Signup and view all the answers

Which hypothalamic hormone is primarily involved in the regulation of growth hormone secretion?

<p>Growth Hormone Releasing Hormone (GHRH) (C)</p> Signup and view all the answers

What effect does Somatostatin Release Inhibiting Factor (SRIF) have on growth hormone?

<p>Inhibits growth hormone secretion (B)</p> Signup and view all the answers

Which combination of hormones does Gonadotropin-Releasing Hormone (GnRH) stimulate the release of?

<p>Follicle Stimulating Hormone (FSH) and Luteinising Hormone (LH) (D)</p> Signup and view all the answers

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Study Notes

Endocrinology

  • The study of hormone secretion, hormone action, and principles of feedback control.

Endocrine vs. Exocrine Glands

  • Endocrine glands are part of the endocrine system and secrete hormones.
  • Exocrine glands secrete substances through a duct, either into the body or onto its surface.

Pancreas

  • Contains both endocrine and exocrine functions.
  • Exocrine glands: Secrete enzymes like proteases, lipases and amylase.
  • Endocrine glands: Secrete hormones like insulin (beta cells) and glucagon (alpha cells).

Hormones

  • Derived from Greek for "to set in motion."
  • Cholesterol is a precursor to many important steroid hormones like estrogen, testosterone, and progesterone.

Mechanisms of Hormone Release

  • Humoral: In response to changing levels of ions or nutrients in the blood (e.g. insulin).
  • Neural: Stimulation by nerves (e.g. oxytocin, ADH from the hypothalamus).
  • Hormonal: Stimulation received from other hormones (e.g. hypothalamic-pituitary axis).

Neuroendocrine System & Neurohormones

  • The neuroendocrine system is how the hypothalamus maintains homeostasis.
  • Regulates reproduction, metabolism, eating and drinking, energy utilization, osmolarity, and blood pressure.
  • Hypothalamus regulates pituitary functions.
  • Neurohormones are substances produced by neurosecretory cells of the nervous system.

Neurotransmitters vs. Neurohormones

  • Neurotransmitters: Act locally in the nervous system.
  • Neurohormones: Travel through the bloodstream to target cells.

Master Regulator – Pituitary Gland

  • Located at the base of the brain.
  • Responsible for producing a variety of hormones, including growth hormone and prolactin.

Hypothalamic-Pituitary Axis

  • Also known as the HPT, HPG, and HPA, depending on the target organs affected.
  • The hypothalamus, pituitary gland, and target organs work together to regulate various bodily functions.

Hypothalamus Role

  • Control many fundamental physiological activities including body temperature, hunger, thirst, sleep, and autonomic nervous system functions.
  • Interface between the endocrine and nervous systems.
  • Synthesize and release neurohormones into the circulatory system through the posterior pituitary.
  • Synthesize and release hypophysiotropic hormones (releasing hormones) into the hypophyseal portal blood system to regulate hormone release from the anterior pituitary.

Hypothalamic Releasing and Inhibiting Hormones

  • Releasing Hormones:
    • CRH (Corticotropin Releasing Hormone): stimulates ACTH release.
    • TRH (Thyrotropin-Releasing Hormone): stimulates TSH release.
    • GnRH (Gonadotropin-Releasing Hormone): stimulates FSH and LH release.
    • GHRH (Growth Hormone Releasing Hormone): stimulates GH release.
  • Inhibiting Hormones:
    • MIH (Melanotropin-Inhibiting Hormone): inhibits MSH secretion.
    • Dopamine: inhibits PRL secretion.
    • SRIF (Somatostatin Release Inhibiting Factor): inhibits STH secretion.

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