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Endocrinology: Hormones and Glucose Metabolism

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21 Questions

What is the primary cause of Type 1 Diabetes Mellitus?

Pancreatic cell destruction

What is the result of glucagon in excess in the body?

Increased glycogenolysis and gluconeogenesis

What is the purpose of testing for pre-diabetes and diabetes beginning at age 45?

To diagnose diabetes at an early stage

What is the criterion for diagnosing diabetes using the HbA1c test?

HbA1c of ≥ 6.5%

What is a common symptom of diabetes in addition to the 3 Ps?

Microvascular problems

What is the primary cause of gestational diabetes?

Metabolic and hormonal changes during pregnancy

What is the effect of somatostatin on endocrine hormones?

Inhibition of insulin, glucagon, and growth hormone

What percentage of diabetes cases are Type 1 Diabetes Mellitus?

5-10%

What is the result of glucagon action on glucose metabolism?

Increased glycogenolysis and gluconeogenesis

What is the primary mechanism of Type 2 Diabetes Mellitus?

Insulin resistance

What is the diagnostic criterion for diabetes using the FPG test?

FPG of ≥ 126 mg/dL

What is the recommended frequency of testing for pre-diabetes and diabetes?

Every 3 years starting at age 45

What is the net effect of growth hormone on glucose levels in the blood?

Increase glucose levels by increasing glycogenolysis

What is the primary mechanism of action of somatostatin in glucose metabolism?

Inhibiting insulin and glucagon secretion

What is the characteristic feature of Type 2 Diabetes Mellitus?

Insulin resistance and impaired insulin secretion

What is the purpose of testing for pre-diabetes and diabetes using the OGTT test?

To screen for diabetes in patients without symptoms

What is the consequence of glucagon excess in the body?

Hyperglycemia

What is the characteristic feature of gestational diabetes?

Metabolic and hormonal changes during pregnancy

What is the recommended test for diagnosing diabetes in patients with symptoms?

Random plasma glucose level

What is the consequence of growth hormone action on glucose metabolism?

Decreased glucose uptake in cells

What is the characteristic feature of hyperosmolar insulin-resistant states?

Hyperglycemia

Test your knowledge of hormones and their effects on glucose metabolism, including growth hormone, thyroxine, and somatostatin. Learn about the role of hormones in regulating blood sugar levels and the pathophysiology of diabetes.

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