Endocrine System: Thyroid, Parathyroid, and Thymus
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Questions and Answers

What is the primary function of the parathyroid gland?

  • To regulate energy utilization and growth
  • To regulate calcium and phosphate homeostasis in the blood (correct)
  • To produce insulin for glucose regulation
  • To produce thymosin for immune system development
  • Which hormone is produced by the adrenal medulla?

  • Thyroxine
  • Aldosterone
  • Epinephrine (Adrenaline) (correct)
  • Cortisol
  • What is the effect of calcitonin produced by the thyroid gland?

  • Increase in glucose metabolism
  • Increase in oxygen consumption and energy utilization
  • Maturation of T-lymphocytes
  • Decrease in calcium ion concentration in body fluids (correct)
  • What is the function of the thymus gland?

    <p>Maturation of immune cells, such as T-lymphocytes</p> Signup and view all the answers

    What is the effect of parathyroid hormone (PTH) on calcium ion concentration in body fluids?

    <p>Increase in calcium ion concentration</p> Signup and view all the answers

    What is the primary function of the adrenal cortex?

    <p>Production of steroid hormones</p> Signup and view all the answers

    What is the effect of mineralocorticoids produced by the adrenal cortex?

    <p>Increase in renal reabsorption of sodium ions and water</p> Signup and view all the answers

    Which hormone stimulates contraction of the uterus and contractile cells of the breast?

    <p>Oxytocin</p> Signup and view all the answers

    Which hormone prevents excess urine production?

    <p>ADH</p> Signup and view all the answers

    What is the location of the thyroid gland?

    <p>Middle anterior part of the neck</p> Signup and view all the answers

    What is the function of calcitonin?

    <p>Regulation of calcium and phosphate homeostasis</p> Signup and view all the answers

    Which hormone stimulates the adrenal cortex to release hormones?

    <p>ACTH</p> Signup and view all the answers

    What is the shape of the thyroid gland?

    <p>Butterfly</p> Signup and view all the answers

    Which hormones are produced by the thyroid gland?

    <p>Thyroxin and Tri-iodothyronine</p> Signup and view all the answers

    Which hormone is responsible for stimulating the release of gastric acid in the stomach?

    <p>Gastrin</p> Signup and view all the answers

    What is the result of thyroid hormone insufficiency in infancy?

    <p>Cretinism</p> Signup and view all the answers

    What is the effect of an overproduction of glucocorticoids?

    <p>Cushing's syndrome</p> Signup and view all the answers

    Prostaglandins play a crucial role in regulating which of the following processes?

    <p>All of the above</p> Signup and view all the answers

    Which hormone is responsible for stimulating the release of hormones from the target gland?

    <p>Releasing substance</p> Signup and view all the answers

    What is the result of iodine insufficiency on the thyroid gland?

    <p>Goiter</p> Signup and view all the answers

    What is the term for the overproduction of growth hormone after the epiphyseal plates have fused?

    <p>Acromegaly</p> Signup and view all the answers

    Where are testes located?

    <p>In the scrotum</p> Signup and view all the answers

    What hormone does the corpus luteum produce?

    <p>Progesterone</p> Signup and view all the answers

    What is the effect of testosterone on males?

    <p>Development of male characteristics</p> Signup and view all the answers

    What hormone is responsible for preparing the uterus for implantation?

    <p>Progesterone</p> Signup and view all the answers

    What is produced by the kidneys?

    <p>Erythropoietin</p> Signup and view all the answers

    What is the effect of oestrogen?

    <p>Follicle maturation</p> Signup and view all the answers

    What is the effect of atrial natriuretic factor (ANF)?

    <p>Powerful vasodilator</p> Signup and view all the answers

    What hormone is produced by the interstitial cells of the testes?

    <p>Testosterone</p> Signup and view all the answers

    What is the function of inhibin?

    <p>Inhibits secretion of FSH</p> Signup and view all the answers

    The [_____________] gland is often referred to as the 'master gland'.

    <p>hypothalamus</p> Signup and view all the answers

    The [_____________] gland is located in the sella turcica.

    <p>pituitary</p> Signup and view all the answers

    The [_____________] gland produces hormones that regulate blood sugar levels.

    <p>pancreas</p> Signup and view all the answers

    The [_____________] contain endocrine tissue that produces hormones that regulate reproduction.

    <p>ovaries and testes</p> Signup and view all the answers

    The [_____________] gland produces hormones that regulate growth and development.

    <p>pituitary</p> Signup and view all the answers

    A [_____________] disorder occurs when the thyroid gland does not produce enough hormones.

    <p>hypothyroid</p> Signup and view all the answers

    The [_____________] gland produces hormones that regulate lactation.

    <p>pituitary</p> Signup and view all the answers

    The [_____________] gland produces hormones that regulate metabolism.

    <p>thyroid</p> Signup and view all the answers

    The pancreas is classified as both exocrine and _______________

    <p>endocrine</p> Signup and view all the answers

    The hormones secreted by the islets of Langerhans in the pancreas include glucagon, insulin and _______________

    <p>somatostatin</p> Signup and view all the answers

    Glucagon, produced by α cells of the pancreas, increases _______________ concentration

    <p>blood glucose</p> Signup and view all the answers

    The pancreas lies _______________ in the abdominal cavity

    <p>retroperitoneally</p> Signup and view all the answers

    Insulin, produced by β cells of the pancreas, decreases _______________ concentration

    <p>blood glucose</p> Signup and view all the answers

    Somatostatin, produced by δ cells of the pancreas, inhibits the secretion of _______________ and glucagon

    <p>insulin</p> Signup and view all the answers

    The adrenal gland is composed of the outer _______________ and the inner medulla

    <p>cortex</p> Signup and view all the answers

    Cortisol, produced by the adrenal cortex, has an _______________ effect

    <p>anti-inflammatory</p> Signup and view all the answers

    Stomach _______ releases gastrin, enteric gastrin, secretin, cholecystokinin, enterocrinin, and gastric inhibiting hormone.

    <p>GIT</p> Signup and view all the answers

    Human chorionic gonadotropin, oestrogen, progesterone, and relaxin are produced by the _______.

    <p>PLACENTA</p> Signup and view all the answers

    Acromegaly is caused by the overproduction of _______ hormone after the epiphyseal plates have fused.

    <p>growth</p> Signup and view all the answers

    The ______ gland is responsible for maturation of T-lymphocytes.

    <p>thymus</p> Signup and view all the answers

    The ______ gland produces hormones that regulate calcium and phosphate in blood.

    <p>parathyroid</p> Signup and view all the answers

    Cretinism is a condition of severely stunted physical and mental growth, resulting from _______ hormone insufficiency in infancy.

    <p>thyroid</p> Signup and view all the answers

    The ______ gland is divided into the outer cortex and inner medulla.

    <p>adrenal</p> Signup and view all the answers

    Goiter is a condition characterized by an enlarged _______ gland, resulting from thyroid hormone hyposecretion.

    <p>thyroid</p> Signup and view all the answers

    Cushing's syndrome results from the hypersecretion of _______ glucocorticoids.

    <p>glucocorticoids</p> Signup and view all the answers

    Glucocorticoids, produced by the adrenal cortex, are involved in ______.

    <p>metabolism</p> Signup and view all the answers

    The ______ gland produces hormones that regulate growth and development.

    <p>thyroid</p> Signup and view all the answers

    Prostaglandins are regulators of cell _______, and are important in normal physiology.

    <p>metabolism</p> Signup and view all the answers

    Feedback control of hormone release involves the regulation of hormone release by the pituitary gland, _______ glands, and target glands.

    <p>stimulating</p> Signup and view all the answers

    Calcitonin, produced by the ______ gland, decreases calcium ion concentration in body fluids.

    <p>thyroid</p> Signup and view all the answers

    Thymosin, produced by the ______ gland, is involved in maturation and functional competence of immune system.

    <p>thymus</p> Signup and view all the answers

    The ______ gland produces hormones that regulate lactation and contraction of the uterus.

    <p>oxytocin</p> Signup and view all the answers

    The ______ produces erythropoietin, which is responsible for the increased production of RBC’s in bone marrow.

    <p>kidneys</p> Signup and view all the answers

    The hormone ______ is responsible for preparing the uterus for implantation and preparing breast for secretory function.

    <p>progesterone</p> Signup and view all the answers

    Atrial Natriuretic factor (ANF) is a powerful ______ hormone secreted by heart muscles.

    <p>vasodilator</p> Signup and view all the answers

    Testes produce ______, which stimulates development of male sexual characteristics.

    <p>testosterone</p> Signup and view all the answers

    The pancreas is classified as both ______ and endocrine.

    <p>exocrine</p> Signup and view all the answers

    Glucagon, produced by α cells of the pancreas, increases ______ concentration.

    <p>glucose</p> Signup and view all the answers

    The ______ gland produces hormones that regulate blood sugar levels.

    <p>pancreas</p> Signup and view all the answers

    Inhibin, produced by interstitial cells of the testes, inhibits secretion of ______.

    <p>FSH</p> Signup and view all the answers

    Study Notes

    Parathyroid Gland

    • Small, rounded mass attached to the posterior surface of the thyroid gland
    • Produces Parathyroid hormone (PTH) which controls homeostasis of calcium and phosphate in blood by activating Vitamin D

    Thymus

    • Plays a role in the immune system
    • Produces thymosin, thymic humoral factor, and thymic factor
    • Responsible for the maturation of T-lymphocytes

    Thyroid, Parathyroid, and Thymus Hormones

    • Thyroid gland produces T3 and T4, which increase energy utilization, oxygen consumption, and growth and development
    • Thyroid gland produces calcitonin, which decreases calcium ion concentration in body fluids
    • Parathyroid gland produces PTH, which increases calcium ion concentration in body fluids
    • Thymus produces thymosin, which is responsible for the maturation and functional competence of the immune system

    Adrenal Gland

    • Located superior to the kidney
    • Divided into the outer cortex and inner medulla
    • Adrenal cortex produces steroid hormones, including glucocorticoids, mineralocorticoids, and gonadocorticoids
    • Adrenal medulla produces hormones controlled by the ANS, including epinephrine and norepinephrine

    Adrenal Hormones

    • Mineralocorticoids (e.g., aldosterone) increase renal reabsorption of sodium ions and water, and decrease renal potassium ion loss

    Pituitary Gland

    • Divided into the neurohypophysis (posterior lobe) and adenohypophysis (anterior lobe)
    • Neurohypophysis stores hormones, including oxytocin and anti-diuretic hormone (ADH)
    • Adenohypophysis releases hormones, including growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), melanocyte-stimulating hormone (MSH), and prolactin (PRL)

    Pituitary Hormones

    • Oxytocin stimulates contraction of the uterus and contractile cells of the breast
    • ADH prevents excess urine production
    • GH promotes general body growth
    • ACTH stimulates the adrenal cortex to release hormones
    • TSH controls the thyroid gland
    • LH and FSH stimulate sexual and reproductive function
    • MSH is related to skin pigmentation
    • PRL initiates milk production in the breast

    Thyroid Gland

    • Located in the middle anterior part of the neck
    • Produces thyroxin (T4) and tri-iodothyronine (T3)
    • Calcitonin is involved in calcium and phosphate homeostasis
    • Rich blood supply allows for the delivery of high levels of hormones in a short period of time

    Endocrine Disorders

    • Acromegaly: overproduction of growth hormone after the epiphyseal plates have fused, leading to bone shape changes, broad facial features, and an enlarged lower jaw
    • Cretinism: severely stunted physical and mental growth due to thyroid hormone insufficiency in infancy
    • Goiter: enlarged thyroid gland due to thyroid hormone hyposecretion, often caused by iodine insufficiency
    • Cushing's syndrome: results from hypersecretion of glucocorticoids, leading to lipid reserves being mobilized, adipose tissue accumulating in the cheeks and base of the neck, and other effects

    Prostaglandins

    • Regulate cell metabolism
    • Important in normal physiology of smooth muscle, blood flow, platelet function, nerve transmission, immune response, secretion, reproduction, and respiration
    • Induce inflammation, promote fever, and intensify pain

    Feedback Control of Hormone Release

    • Regulation involves the production of releasing substances or inhibiting substances
    • Involves the release of hormone from the pituitary gland, stimulation of hormone release by the target gland, and the hormone exerting its normal effect and influencing further release of a releasing or inhibiting substance

    Testes and Ovaries

    • Testes: located within the scrotum, produce testosterone, and stimulate the development of male sexual characteristics
    • Ovaries: located in the pelvic cavity, produce oestrogen and progesterone, and are responsible for the development and maintenance of female characteristics and the menstrual cycle

    Hormones of the Reproductive System

    • Testosterone: involved in the maturation of sperm and male secondary sex characteristics
    • Inhibin: inhibits the secretion of FSH
    • Oestrogen: involved in follicle maturation and female secondary sex characteristics
    • Progesterone: prepares the uterus for implantation and prepares the breast for secretory function

    Endocrine System

    • The endocrine system is a network of ductless glands that produce and secrete hormones that regulate various bodily functions.
    • The system consists of major endocrine glands, including the hypothalamus, pituitary gland, thyroid gland, parathyroid gland, thymus, adrenal gland, pancreas, kidneys, heart, digestive tract, placenta, testes, ovaries, and pineal gland.

    Hypothalamus

    • The hypothalamus is the "master gland" that controls the body's temperature, hunger, and thirst, and regulates hormone secretion.
    • It receives information from the body and interprets and evaluates it, sending outgoing messages via nerves or hormones.

    Pituitary Gland

    • The pituitary gland is a pea-sized mass of glandular tissue located in the sella turcica, connected to the hypothalamus by a slender stalk called the infundibulum.
    • It has two parts: the neurohypophysis and adenohypophysis, and indirectly controls growth, metabolism, sexual reproduction, and lactation.

    Adrenal Gland

    • The adrenal gland is divided into the outer cortex and inner medulla.
    • The adrenal cortex secretes steroid hormones, including glucocorticoids, mineralocorticoids, and gonadocorticoids.
    • The adrenal medulla secretes hormones controlled by the autonomic nervous system, including epinephrine (adrenaline) and norepinephrine (noradrenaline).

    Pancreas

    • The pancreas is a flattened organ located retroperitoneally and transversely across the posterior abdominal wall.
    • It is classified as both exocrine and endocrine, with the islets of Langerhans secreting glucagon, insulin, and growth hormone-inhibiting hormone.

    Parathyroid Gland

    • The parathyroid gland is a small, rounded mass attached to the posterior surface of the thyroid gland.
    • It produces parathyroid hormone (PTH), which controls the homeostasis of calcium and phosphate in the blood by activating vitamin D.

    Thymus

    • The thymus plays a role in the immune system, producing thymosin, thymic humoral factor, and thymic factor.
    • It is responsible for the maturation of T-lymphocytes.

    Thyroid Gland

    • The thyroid gland is located in the neck and produces triiodothyronine (T3) and thyroxine (T4), which regulate energy utilization, growth, and development.
    • It also produces calcitonin, which decreases calcium ion concentration in body fluids.

    Adrenal Hormones

    • The adrenal cortex secretes mineralocorticoids (e.g., aldosterone), glucocorticoids (e.g., cortisol), and gonadocorticoids (e.g., estrogen and androgens).
    • The adrenal medulla secretes epinephrine (adrenaline) and norepinephrine (noradrenaline), which increase cardiac activity, blood pressure, and glycogen breakdown, and mobilize lipid reserves.

    Reproductive System Hormones

    • Testes produce testosterone, which stimulates the development of male sexual characteristics.
    • Ovaries produce estrogen and progesterone, which are responsible for female sexual characteristics and the menstrual cycle.

    Other Endocrine Tissues

    • The kidneys produce erythropoietin, which stimulates the production of red blood cells.
    • The heart produces atrial natriuretic factor (ANF), a powerful vasodilator hormone.

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    This quiz covers the functions and characteristics of the thyroid, parathyroid, and thymus glands, including their roles in hormone production and regulation.

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