Endocrine System: Thyroid Gland Anatomy and Hormones Quiz

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Questions and Answers

What is the main hormone secreted by the Parafollicular cells of the thyroid gland?

  • Thyroxine
  • Thyroglobulin
  • Calcitonin (correct)
  • Triiodothyronine

Where are the thyroid glands typically located in most mammals?

  • Caudal to the trachea (correct)
  • Cranial to the trachea
  • Dorsal to the trachea
  • At the level of the third tracheal ring

Which molecule is a major substrate that combines with iodine to form thyroid hormones?

  • Tyrosine (correct)
  • Iodide
  • Thyroglobulin
  • Calcitonin

What is the main storage site of active thyroid hormones within the thyroid gland?

<p>Colloid (A)</p> Signup and view all the answers

How do catecholamines and thyroid hormones differ in terms of blood transport?

<p>Thyroid hormones circulate unbound in the blood (B)</p> Signup and view all the answers

How is iodine transported into the thyroid follicle cells?

<p>Active transport with sodium ions (B)</p> Signup and view all the answers

Which enzyme facilitates the synthesis of thyroid hormones within the thyroid follicle lumen?

<p>Thyroid Peroxidase (B)</p> Signup and view all the answers

What is the function of follicular cells within the thyroid gland?

<p>Synthesis of thyroid hormones (A)</p> Signup and view all the answers

Which structure in the thyroid gland is rich in thyroglobulin and serves as a key storage location for active thyroid hormones?

<p>Thyroid Follicle Lumen (A)</p> Signup and view all the answers

What is the role of Tyrosine in the synthesis of thyroid hormones?

<p>Combines with iodine to form thyroid hormones (A)</p> Signup and view all the answers

From where does iodine originate for thyroid hormone synthesis in the body?

<p>Intestinal tract (A)</p> Signup and view all the answers

What is the primary role of colloid within the thyroid follicles?

<p>Storage of active thyroid hormones (C)</p> Signup and view all the answers

What is the end product when one iodine molecule attaches to the tyrosyl ring of tyrosine amino acid on thyroglobulin protein?

<p>Monoiodotyrosine (MIT) (B)</p> Signup and view all the answers

Which statement about thyroid hormone T3 is true?

<p>Produced by peripheral deiodination of T4 in target tissues (B)</p> Signup and view all the answers

What enzyme-dependent process mainly produces T3 from T4 in target tissues?

<p>Deiodinases (D)</p> Signup and view all the answers

What is the primary function of thyroxine-binding globulin (TBG) in the transport of thyroid hormones?

<p>Transport in plasma (D)</p> Signup and view all the answers

Which organ is primarily responsible for the conjugation formation of thyroid hormones?

<p>Liver (A)</p> Signup and view all the answers

Which is a common symptom of hyperthyroidism in cats?

<p>Increased appetite (polyphagia) (D)</p> Signup and view all the answers

What is a primary cause of hypothyroidism in dogs?

<p>Autoimmune thyroiditis (C)</p> Signup and view all the answers

What is a common symptom of hypothyroidism related to metabolism in affected animals?

<p>Lethargy and obesity (B)</p> Signup and view all the answers

What is a possible cause of iodine deficiency in cattle, sheep, and goats?

<p>Inadequate dietary intake of iodine (D)</p> Signup and view all the answers

Which term describes the enlargement of the thyroid glands due to iodine deficiency?

<p>Goiter (B)</p> Signup and view all the answers

What is the main function of the follicular cells within the thyroid gland?

<p>Synthesize thyroid hormones (C)</p> Signup and view all the answers

In terms of blood transport, how do catecholamines differ from thyroid hormones?

<p>Catecholamines bind to cell membrane receptors (C)</p> Signup and view all the answers

What is a significant difference between catecholamines and thyroid hormones in terms of their properties?

<p>Thyroid hormones are hydrophilic (A)</p> Signup and view all the answers

Which structure within the thyroid gland serves as the main storage site for active thyroid hormones?

<p>Thyroid follicle lumen (A)</p> Signup and view all the answers

What is the role of Thyroid Peroxidase in the synthesis of thyroid hormones?

<p>Converts iodide into iodine (A)</p> Signup and view all the answers

Which anatomical feature of the thyroid glands allows mammals to cope with iodine deprivation?

<p>Colloid storage (B)</p> Signup and view all the answers

What is the primary role of Parafollicular cells in the thyroid gland?

<p>Secrete calcitonin (A)</p> Signup and view all the answers

How is iodine transported into the thyroid follicle cells?

<p>Na+/I- cotransporter (A)</p> Signup and view all the answers

What is the major molecule involved in the formation of thyroid hormones?

<p>Tyrosine (C)</p> Signup and view all the answers

What is the function of Thyroid Peroxidase in thyroid hormone synthesis?

<p>Assisting in thyroid hormone production steps within the lumen (D)</p> Signup and view all the answers

Where does iodine originate from for thyroid hormone synthesis?

<p>Dietary sources (D)</p> Signup and view all the answers

What is the role of tyrosine in thyroid hormone synthesis?

<p>To combine with iodine to form thyroid hormones (A)</p> Signup and view all the answers

What is the main cause of hyperthyroidism in cats?

<p>Hyperplasia or tumors of the thyroid gland (B)</p> Signup and view all the answers

Which symptom is typically associated with hypothyroidism in dogs?

<p>Reproductive disorders (D)</p> Signup and view all the answers

What is a primary cause of hypothyroidism associated with strong breed disposition in dogs?

<p>Lymphocytic thyroiditis (B)</p> Signup and view all the answers

Which species is most commonly affected by iodine deficiency resulting in goiter?

<p>Cattle (C)</p> Signup and view all the answers

What is a symptom related to hypermetabolism seen in cats with hyperthyroidism?

<p>Increased appetite (polyphagia) (D)</p> Signup and view all the answers

Which thyroid pathology is more common in cats than in dogs?

<p>Hyperthyroidism (B)</p> Signup and view all the answers

What is the end product when two iodine molecules attach to the tyrosyl ring of tyrosine amino acid on thyroglobulin protein?

<p>Triiodothyronine (T3) (C)</p> Signup and view all the answers

Which enzyme-dependent process mainly produces T3 from T4 in target tissues?

<p>Deiodination (D)</p> Signup and view all the answers

What is the primary function of thyroxine-binding globulin (TBG) in the transport of thyroid hormones?

<p>Transport of thyroid hormones in plasma (A)</p> Signup and view all the answers

Which enzyme facilitates the synthesis of thyroid hormones within the thyroid follicle lumen?

<p>Lysosomes (D)</p> Signup and view all the answers

Where are active thyroid hormones stored within the thyroid gland?

<p>Colloid (D)</p> Signup and view all the answers

What is the metabolic process that interferes with hormone concentrations and can cause high levels of thyroid hormones in the blood?

<p>Metabolic clearance rate (D)</p> Signup and view all the answers

What is the primary role of thyroid hormones in cellular metabolism?

<p>Increase mitochondrial activity (B)</p> Signup and view all the answers

How do thyroid hormones influence carbohydrate metabolism?

<p>Increase glucose absorption (A)</p> Signup and view all the answers

What is the function of C-cells or Parafollicular cells in the thyroid gland?

<p>Secrete calcitonin (C)</p> Signup and view all the answers

Which substance is a major substrate for the formation of thyroid hormones?

<p>Tyrosine (D)</p> Signup and view all the answers

How is iodide transported into the thyroid follicle cells?

<p>Active transport with Na+/I- cotransporter (D)</p> Signup and view all the answers

What enzyme facilitates the synthesis of thyroid hormones within the thyroid follicle lumen?

<p>Thyroid Peroxidase (C)</p> Signup and view all the answers

Where do thyroid follicle cells trap iodide from?

<p>Intestinal tract (D)</p> Signup and view all the answers

What is the role of Thyroid Peroxidase in the synthesis of thyroid hormones?

<p>Facilitates the synthesis of thyroid hormones (B)</p> Signup and view all the answers

What is the primary function of thyroid hormones in target tissues?

<p>Stimulate metabolic activity (C)</p> Signup and view all the answers

Which anatomical feature of the thyroid gland is rich in thyroglobulin and serves as a key storage location for active thyroid hormones?

<p>Colloid (C)</p> Signup and view all the answers

In most mammals, where are the thyroid glands typically located?

<p>Caudal to the trachea (B)</p> Signup and view all the answers

What is the primary cause of hypothyroidism in dogs?

<p>Iodine deficiency (B)</p> Signup and view all the answers

Which enzyme-dependent process mainly produces T3 from T4 in target tissues?

<p>Deiodination (B)</p> Signup and view all the answers

What is the main storage of active thyroid hormones within the thyroid gland?

<p>Thyroid follicle lumen (B)</p> Signup and view all the answers

What is the end product when 1 molecule of iodine attaches to the tyrosyl ring on thyroglobulin protein?

<p>DIIODOTYROSINE (DIT) (C)</p> Signup and view all the answers

Which enzyme is primarily responsible for the metabolic breakdown of thyroid hormones in liver, skeletal muscle, and kidneys?

<p>Iodothyronine Deiodinases (C)</p> Signup and view all the answers

What symptom can hypothyroid individuals present due to the effect of thyroid hormones on lipid metabolism?

<p>Hyperlipidemia (C)</p> Signup and view all the answers

Which physiological action of thyroid hormones affects the rate of ATP synthesis by increasing mitochondria activity?

<p>Increase in basal metabolic rate (C)</p> Signup and view all the answers

How are T3 and T4 released from thyroid follicle cells into the bloodstream?

<p>By passive diffusion (C)</p> Signup and view all the answers

What is the primary function of Thyroxine-binding Globulin (TBG) in the transport of thyroid hormones?

<p>Transport thyroid hormones in blood (C)</p> Signup and view all the answers

In which situation can a decreased metabolic clearance rate of thyroid hormones lead to high concentrations in the blood?

<p>In liver disease (C)</p> Signup and view all the answers

Which of the following symptoms is typically associated with hyperthyroidism in cats?

<p>Increased thirst and urination (C)</p> Signup and view all the answers

What is a common cause of hypothyroidism in dogs with a strong breed disposition?

<p>Autoimmune thyroiditis (A)</p> Signup and view all the answers

Which of the following is a primary symptom related to hypometabolism in animals with hypothyroidism?

<p>Constipation (D)</p> Signup and view all the answers

What is a common cause of iodine deficiency in cattle, sheep, and goats leading to goiter?

<p>Inadequate dietary iodine intake (B)</p> Signup and view all the answers

In which animals is hyperthyroidism most commonly observed?

<p>Cats (C)</p> Signup and view all the answers

What is the main cause of hyperthyroidism in cats?

<p>Hyperplasia or tumors of the thyroid gland (B)</p> Signup and view all the answers

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