Endocrine System Quiz
58 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following is a correct statement about the endocrine system?

  • The endocrine system is responsible for regulating blood sugar levels. (correct)
  • The endocrine system is responsible for rapid communication between cells.
  • The endocrine system uses neurotransmitters to communicate.
  • The endocrine system uses hormones to communicate. (correct)
  • What is the primary difference between endocrine and exocrine glands?

  • Exocrine glands secrete hormones, while endocrine glands secrete enzymes.
  • Endocrine glands have ducts, while exocrine glands do not.
  • Exocrine glands are responsible for internal secretions, while endocrine glands are responsible for external secretions.
  • Endocrine glands secrete substances into the bloodstream, while exocrine glands secrete substances onto epithelial surfaces. (correct)
  • Which of the following is NOT a characteristic of hormones?

  • Hormones are secreted into the extracellular matrix. (correct)
  • Hormones travel in the bloodstream.
  • Hormones are chemical messengers.
  • Hormones are produced by cells.
  • What is the main function of the endocrine system?

    <p>To regulate the body's internal environment. (A)</p> Signup and view all the answers

    What is the role of the hypothalamus in the endocrine system?

    <p>To control the release of hormones from the pituitary gland. (D)</p> Signup and view all the answers

    What is the main difference between the nervous and endocrine systems in terms of their response speed?

    <p>The nervous system reacts quickly, the endocrine system reacts slowly. (A)</p> Signup and view all the answers

    How do the nervous and endocrine systems differ in their ability to adapt to long-term stimuli?

    <p>The endocrine system is better at adapting to long-term stimuli. (B)</p> Signup and view all the answers

    Which of the following statements accurately describes the area of effect for the nervous and endocrine systems?

    <p>The endocrine system has widespread effects, the nervous system has targeted effects. (C)</p> Signup and view all the answers

    How do the nervous and endocrine systems interact and influence each other?

    <p>Neurotransmitters affect the endocrine system, and hormones affect the nervous system. (D)</p> Signup and view all the answers

    What is a characteristic shared by both the nervous system and the endocrine system?

    <p>Both systems have specialized cells called neuroendocrine cells. (A)</p> Signup and view all the answers

    Which of these hormones is primarily responsible for regulating blood calcium levels?

    <p>Parathyroid hormone (PTH) (A)</p> Signup and view all the answers

    Which hormone, produced by the pineal gland, is known to influence the timing of puberty and is involved in circadian rhythms?

    <p>Melatonin (D)</p> Signup and view all the answers

    Which of the following hormones is secreted by the adrenal medulla, and its primary function is to prepare the body for 'fight or flight' responses?

    <p>Epinephrine (D)</p> Signup and view all the answers

    Which hormone, produced by the pancreas, is responsible for lowering blood glucose levels by stimulating cells to absorb glucose and store or metabolize it?

    <p>Insulin (A)</p> Signup and view all the answers

    Which of the following statements about the relationship between the adrenal medulla and cortex is CORRECT?

    <p>The adrenal medulla is dependent on the cortex for its function. (D)</p> Signup and view all the answers

    Which of these hormones is NOT part of the hyperglycemic group, meaning that it does NOT increase blood glucose levels?

    <p>Insulin (D)</p> Signup and view all the answers

    Which of the following organs/tissues plays a role in the production of erythropoietin, a hormone that stimulates bone marrow to produce red blood cells?

    <p>Kidneys (D)</p> Signup and view all the answers

    Which of the following hormones is primarily responsible for stimulating osteoblast activity and bone formation, particularly in children?

    <p>Calcitonin (D)</p> Signup and view all the answers

    What structure connects the hypothalamus to the anterior pituitary?

    <p>Hypophysial portal system (A)</p> Signup and view all the answers

    What is the main function of the hormone aldosterone, secreted by the adrenal cortex?

    <p>Regulating electrolyte balance, especially sodium and potassium (D)</p> Signup and view all the answers

    Which of the following hormones is NOT secreted by the anterior pituitary?

    <p>Antidiuretic hormone (B)</p> Signup and view all the answers

    The hormone leptin is secreted by which organ/tissue and what is its primary function?

    <p>Adipose tissue; slows appetite (B)</p> Signup and view all the answers

    What is the function of prolactin?

    <p>Stimulates milk production (B)</p> Signup and view all the answers

    What is the primary function of the neurohypophysis?

    <p>Stores and releases hormones produced by the hypothalamus (C)</p> Signup and view all the answers

    Which pair of hormones is correctly matched with its primary function?

    <p>Growth hormone: promotes growth and development, especially during childhood (D)</p> Signup and view all the answers

    Which hormone, secreted by the liver, promotes intestinal absorption of iron?

    <p>Hepcidin (D)</p> Signup and view all the answers

    Which of the following hormones is primarily responsible for stimulating the adrenal cortex to secrete cortisol?

    <p>Adrenocorticotropic hormone (D)</p> Signup and view all the answers

    Which of these hormones is produced in the hypothalamus and released from the posterior pituitary?

    <p>Antidiuretic hormone (A)</p> Signup and view all the answers

    Which of the following statements about the 'glucose-sparing effect' is CORRECT?

    <p>It is a process where the body uses fatty acids as fuel, conserving glucose for the brain. (B)</p> Signup and view all the answers

    Which of these hormones promotes milk ejection during lactation?

    <p>Oxytocin (A)</p> Signup and view all the answers

    Which of the following hormones is NOT produced by the gonads (ovaries or testes)?

    <p>Thymosin (B)</p> Signup and view all the answers

    Which of the following statements about the anterior pituitary is TRUE?

    <p>It is connected to the hypothalamus by a network of blood vessels. (D)</p> Signup and view all the answers

    Which of the following hormones has a negative feedback mechanism for its own secretion?

    <p>Thyroid hormone (C)</p> Signup and view all the answers

    Which of the following hormones is NOT regulated by a hypothalamic releasing or inhibiting hormone?

    <p>Antidiuretic hormone (D)</p> Signup and view all the answers

    What is the primary function of the enteroendocrine cells found in the stomach and small intestines?

    <p>Secrete hormones that regulate digestion (D)</p> Signup and view all the answers

    How does the hypothalamus influence the release of hormones from the anterior pituitary?

    <p>By releasing hormones that travel through the hypophysial portal system. (A)</p> Signup and view all the answers

    What is the primary function of gonadotropin-releasing hormone (GnRH)?

    <p>To stimulate the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) (B)</p> Signup and view all the answers

    Which of the following hormones is primarily responsible for stimulating the release of thyroid hormone from the thyroid gland?

    <p>Thyroid-stimulating hormone (D)</p> Signup and view all the answers

    Which of the following statements about the posterior pituitary is CORRECT?

    <p>It stores and releases hormones produced by the hypothalamus. (C)</p> Signup and view all the answers

    What is the function of somatostatin?

    <p>Inhibits the release of growth hormone and thyroid-stimulating hormone (C)</p> Signup and view all the answers

    What is the primary function of oxytocin?

    <p>Stimulates the release of milk from the mammary glands (A)</p> Signup and view all the answers

    What is the role of the infundibulum in the pituitary gland?

    <p>It is the stalk that connects the hypothalamus to the pituitary gland. (D)</p> Signup and view all the answers

    Which of the following hormones is NOT produced by the anterior pituitary?

    <p>Antidiuretic hormone (ADH) (A)</p> Signup and view all the answers

    Which of the following is a correct statement about the secretion of steroid hormones?

    <p>Steroid hormones are released as fast as they are synthesized by diffusion through the cell surface. (B), Steroid hormone secretion can be significantly increased by the presence of peptide hormones. (C)</p> Signup and view all the answers

    Which of the following hormones is NOT synthesized from the amino acid tyrosine?

    <p>Melatonin (B)</p> Signup and view all the answers

    Which of the following is a correct statement about hormone transport?

    <p>Transport proteins protect hormones from degradation by enzymes and filtration by the kidneys. (B)</p> Signup and view all the answers

    Which of the following is an example of a synergistic effect of hormone interactions?

    <p>FSH and testosterone working together to stimulate sperm production. (D)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the alarm reaction stage of the General Adaptation Syndrome (GAS)?

    <p>Suppression of the immune system. (C)</p> Signup and view all the answers

    Which of the following statements accurately describes the role of cortisol in the stage of resistance?

    <p>Cortisol promotes the breakdown of fat and protein to provide alternate fuels for metabolism. (C)</p> Signup and view all the answers

    Which of the following is a correct statement about eicosanoids?

    <p>Eicosanoids act as both paracrines and autocrines. (A)</p> Signup and view all the answers

    Which of the following is an example of a humoral stimulus for hormone secretion?

    <p>Rising blood glucose levels stimulating the release of insulin. (A)</p> Signup and view all the answers

    Which of the following is a correct statement about the mechanism of action of peptide hormones?

    <p>Peptide hormones bind to surface receptors and activate intracellular processes through second messengers. (A)</p> Signup and view all the answers

    Which of the following is an example of a hormone that undergoes up-regulation?

    <p>Thyroid hormone in individuals with hypothyroidism. (D)</p> Signup and view all the answers

    Which of the following is NOT a characteristic of hypersecretion of growth hormone?

    <p>Short stature in children. (C)</p> Signup and view all the answers

    Which of the following is a correct statement about the pathogenesis of diabetes mellitus?

    <p>Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes. (C)</p> Signup and view all the answers

    Which of the following is a correct statement about the treatment of diabetes mellitus?

    <p>Type 2 diabetes is typically treated with weight loss, exercise, and insulin. (D)</p> Signup and view all the answers

    Which of the following is NOT a common symptom of Cushing syndrome?

    <p>Weight loss due to increased metabolism. (B)</p> Signup and view all the answers

    Which of the following is a correct statement about the effects of cortisol on the immune system?

    <p>Cortisol suppresses the immune response. (A)</p> Signup and view all the answers

    Flashcards

    Endocrine System

    Glands, tissues, and cells that secrete hormones.

    Hormones

    Chemical messengers transported in the bloodstream to stimulate responses in distant cells.

    Neurotransmitters

    Chemicals released from neurons to transmit signals across synapses.

    Differences in Glands

    Exocrine glands have ducts for external secretions, whereas endocrine glands do not and release hormones internally.

    Signup and view all the flashcards

    Four Mechanisms of Communication

    Gap junctions, neurotransmitters, paracrines, and hormones are key methods of cell signaling.

    Signup and view all the flashcards

    Speed of response

    Nervous system reacts quickly in milliseconds, endocrine system reacts slowly over seconds or days.

    Signup and view all the flashcards

    Adaptation to stimuli

    Nervous system adapts quickly to long-term stimuli; endocrine system adapts slowly.

    Signup and view all the flashcards

    Area of effect

    Nervous system has targeted effects on one organ; endocrine system has general effects on many organs.

    Signup and view all the flashcards

    Similar substances in both systems

    Norepinephrine, dopamine, and antidiuretic hormone act as both hormones and neurotransmitters.

    Signup and view all the flashcards

    Target organs or cells

    Organs or cells with receptors for a hormone that can respond to it, some can convert hormones to active forms.

    Signup and view all the flashcards

    Hypothalamus

    A brain region that controls primitive functions like childbirth and sex drive, connected to the pituitary gland.

    Signup and view all the flashcards

    Pituitary Gland

    A gland with anterior and posterior parts, responsible for releasing hormones that regulate various body functions.

    Signup and view all the flashcards

    Infundibulum

    The stalk that connects the pituitary gland to the hypothalamus.

    Signup and view all the flashcards

    Anterior Pituitary

    The front portion of the pituitary, responsible for producing and releasing hormones like FSH and LH.

    Signup and view all the flashcards

    Posterior Pituitary

    The back portion of the pituitary that stores and releases hormones made by the hypothalamus.

    Signup and view all the flashcards

    Thyroid-Releasing Hormone (TRH)

    A hormone from the hypothalamus that stimulates the anterior pituitary to release TSH.

    Signup and view all the flashcards

    Oxytocin

    A hormone produced by the hypothalamus that stimulates uterine contractions and milk ejection during lactation.

    Signup and view all the flashcards

    Antidiuretic Hormone (ADH)

    A hormone that promotes water retention in the kidneys, helping maintain blood pressure.

    Signup and view all the flashcards

    Corticotropin-Releasing Hormone (CRH)

    A hormone from the hypothalamus that induces the release of ACTH from the anterior pituitary.

    Signup and view all the flashcards

    Follicle-Stimulating Hormone (FSH)

    A hormone released by the anterior pituitary that stimulates ovarian follicles and sperm production.

    Signup and view all the flashcards

    Luteinizing Hormone (LH)

    A hormone from the anterior pituitary that triggers ovulation and testosterone production.

    Signup and view all the flashcards

    Prolactin (PRL)

    A hormone that stimulates milk production in mammary glands after childbirth.

    Signup and view all the flashcards

    Adrenocorticotropic Hormone (ACTH)

    A hormone that stimulates the adrenal cortex to produce glucocorticoids in response to stress.

    Signup and view all the flashcards

    Negative Feedback

    A regulatory mechanism that counteracts change, helping maintain homeostasis in hormone levels.

    Signup and view all the flashcards

    Positive Feedback

    A process where a hormone release leads to more hormone release, e.g., oxytocin during childbirth.

    Signup and view all the flashcards

    Growth Hormone (GH)

    Promotes growth and metabolic processes; affects bones, muscles, and fat.

    Signup and view all the flashcards

    Insulin-like Growth Factors (IGF)

    Produced by the liver, they prolong the action of growth hormone.

    Signup and view all the flashcards

    Pineal Gland

    Produces melatonin, influences sleep patterns and circadian rhythms.

    Signup and view all the flashcards

    Thymus

    Maturation site for T cells, affecting the immune system.

    Signup and view all the flashcards

    Thyroid Gland

    Largest purely endocrine gland; regulates metabolism via T3 and T4.

    Signup and view all the flashcards

    Parathyroid Hormone (PTH)

    Increases blood calcium levels by promoting bone resorption.

    Signup and view all the flashcards

    Adrenal Medulla

    Inner part of adrenal gland, releases catecholamines like epinephrine.

    Signup and view all the flashcards

    Cortisol

    A glucocorticoid that helps manage stress responses and metabolism.

    Signup and view all the flashcards

    Glucagon

    Hormone that raises blood glucose levels by promoting liver glucose production.

    Signup and view all the flashcards

    Ovaries

    Female reproductive glands producing hormones like estradiol and progesterone.

    Signup and view all the flashcards

    Testes

    Male reproductive glands that secrete testosterone and regulate sperm production.

    Signup and view all the flashcards

    Erythropoietin

    Hormone from the kidneys that stimulates red blood cell production.

    Signup and view all the flashcards

    Hormone Classes

    Categorized into steroids, monoamines, and peptides based on their chemical structure.

    Signup and view all the flashcards

    Sex Steroids

    Hormones like estrogen produced by gonads.

    Signup and view all the flashcards

    Corticosteroids

    Hormones like cortisol produced by adrenal glands.

    Signup and view all the flashcards

    Monoamines

    Hormones made from amino acids, includes catecholamines and melatonin.

    Signup and view all the flashcards

    Peptide Hormones

    Hormones formed by chains of amino acids.

    Signup and view all the flashcards

    Thyroid Hormone Synthesis

    Thyroid hormones are formed using tyrosines and iodide.

    Signup and view all the flashcards

    Hormone Secretion Patterns

    Hormones are secreted in varying rates based on body needs.

    Signup and view all the flashcards

    Neural Stimuli

    Hormone release triggered by nerve signals.

    Signup and view all the flashcards

    Humoral Stimuli

    Hormones released based on blood composition changes.

    Signup and view all the flashcards

    Transport of Hormones

    Steroid hormones are hydrophobic and require transport proteins.

    Signup and view all the flashcards

    Hormone Receptors

    Proteins that bind hormones and trigger cellular responses.

    Signup and view all the flashcards

    Peptide and Catecholamine Action

    Act on cell surface receptors via second messengers.

    Signup and view all the flashcards

    Steroid Hormone Action

    Penetrates cell membranes and binds to internal receptors.

    Signup and view all the flashcards

    Signal Amplification

    One hormone molecule can activate many enzymes.

    Signup and view all the flashcards

    Hormone Interactions

    Hormones can have synergistic, permissive, or antagonistic effects.

    Signup and view all the flashcards

    Diabetes Symptoms

    Increased urine output, thirst, and hunger due to insulin issues.

    Signup and view all the flashcards

    Study Notes

    Endocrine System Overview

    • The endocrine system and nervous system are specialized for communication and coordination in humans.
    • The endocrine system uses hormones, whereas the nervous system uses neurotransmitters.
    • Four principal mechanisms of cellular communication exist: gap junctions, neurotransmitters, paracrines, and hormones.
    • Endocrine system comprises glands, tissues, and cells that secrete hormones.
    • Endocrinology studies this system and its disorders.
    • Endocrine glands are traditional hormone sources.
    • Hormones are chemical messengers transported by blood, stimulating physiological responses in distant target cells.

    Endocrine vs. Exocrine Glands

    • Exocrine glands have ducts, carrying secretions externally (e.g., digestive tract). Secretions have extracellular effects.
    • Endocrine glands lack ducts; contain dense, fenestrated capillary networks facilitating hormone uptake. Secretions have intracellular effects.

    Nervous vs. Endocrine Systems

    • Speed and persistence of response differ significantly. Nervous system responds rapidly and effects are short-lived; endocrine system response is slow but effects can persist for extended periods.
    • Adaptation to long-term stimuli differs. Nervous system quickly adapts, while endocrine system adapts more slowly.
    • Effects are targeted and specific in the nervous system; general and widespread in the endocrine system.
    • Several chemicals (e.g., norepinephrine, dopamine, ADH) function as both hormones and neurotransmitters, or have similar effects on target cells.
    • The two systems interact; neurotransmitters can affect glands, and hormones affect neurons.
    • Neuroendocrine cells share characteristics of both systems.
    • Target cells are those possessing receptors for a hormone to respond to it.

    The Hypothalamus

    • Functions as a control center for primitive functions (childbirth, sex drive) and works with the pituitary gland.
    • Connects to the pituitary via the infundibulum (a stalk).
    • Located in the floor and walls of the third ventricle.
    • Anterior pituitary: anterior ¾ of the pituitary; connected to hypothalamus by hypophysial portal system (primary-secondary capillaries).
    • Posterior pituitary: posterior ¼ of pituitary; nerve tissue, not a true gland and stores/releases hormones from hypothalamus.
    • Hypothalamic hormones affect the anterior pituitary (e.g., TRH, CRH, GnRH, GRH, PIH, somatostatin) and the posterior pituitary (OT, ADH).

    Pituitary Gland

    • Located in the sella turcica of the sphenoid bone.
    • Shaped like a kidney bean.
    • Composed of two structures (anterior and posterior pituitary) with independent origins and function.

    Anterior Pituitary Hormones

    • Six primary hormones are synthesized and secreted: FSH, LH, TSH, ACTH, PRL, and GH.
    • Gonadotropins (FSH and LH) regulate gonads.
    • TSH stimulates thyroid hormone secretion.
    • ACTH stimulates adrenal cortex glucocorticoid secretion.
    • PRL stimulates mammary gland milk synthesis.
    • GH stimulates cell mitosis and differentiation.

    Posterior Pituitary Hormones

    • Two hormones produced in the hypothalamus and stored/released in posterior pituitary: ADH (vasopressin) and oxytocin.
    • ADH increases water retention, reducing urine and preventing dehydration.
    • Oxytocin is released during sexual arousal and orgasm, childbirth, and lactation, fostering bonding.

    Control of Pituitary Secretion

    • Rates vary; regulated by the hypothalamus, brain, and target organs.

    Negative Feedback

    • Increased target organ hormone levels inhibit hypothalamic and/or pituitary hormone release to maintain homeostasis.

    Growth Hormone (GH)

    • Widespread effects; boosts protein synthesis, lipid metabolism, and carbohydrate metabolism.
    • Induces liver to release IGFs (insulin-like growth factors) to stimulate target cells.
    • GH has a short half-life; IGFs have a longer half-life, prolonging action.
    • Impacts bone growth, thickening, and remodeling, particularly during development.
    • Secretion is high during initial sleep hours and can be triggered by exercise or hunger.
    • GH levels decline with age.

    Pineal Gland

    • Located beneath the posterior end of the corpus callosum.
    • Undergoes involution (shrinkage) after age 7.
    • Synthesizes melatonin at night.
    • Influences puberty timing and circadian rhythms.
    • Seasonal affective disorder (SAD) symptoms are reduced by light exposure.

    Thymus Gland

    • Bilobed gland superior to the heart in the mediastinum; involved in the endocrine, lymphatic, and immune systems.
    • Undergoes involution after puberty.
    • Site of maturation for T cells.
    • Secretes hormones (thymopoietin, thymosin, thymulin).

    Thyroid Gland

    • Largest purely endocrine gland.
    • Two lobes and an isthmus below the larynx, dark reddish brown.
    • Thyroid follicles contain colloid, surrounded by follicular cells (simple cuboidal epithelium).
    • Secretes thyroxine (T4) and Triiodothyronine (T3) in response to TSH.
    • Increases metabolic rate, oxygen consumption, heat production, appetite, growth hormone secretion, alertness, and reflex speed.
    • Parafollicular cells secrete calcitonin to regulate blood calcium.

    Parathyroid Glands

    • Embedded in the posterior thyroid.
    • Secrete parathyroid hormone (PTH) to increase blood calcium.
    • Promotes calcitriol synthesis for calcium absorption.

    Adrenal Glands

    • Composed of cortex and medulla.
    • Medulla: inner core, modified sympathetic neurons (chromaffin cells). Secretes epinephrine, norepinephrine, and dopamine, in response to stress.
      • Increases alertness, mobilizes energy, has a glucose-sparing effect, and has widespread impact on body function (blood pressure, heart rate, blood flow, metabolic rate).
    • Cortex: secretes corticosteroids from three zones:
      • Zona glomerulosa: mineralocorticoids (aldosterone) regulates electrolyte balance, especially sodium content.
      • Zona fasciculata: glucocorticoids (cortisol) regulate metabolism of glucose and other fuels; promotes fat and protein catabolism and gluconeogenesis.
      • Zona reticularis: androgens for libido and prenatal male development.

    Pancreatic Islets

    • Endocrine tissue interspersed in exocrine pancreas.
    • Alpha cells secrete glucagon (raises blood glucose).
    • Beta cells secrete insulin (lowers blood glucose).
    • Delta cells secrete somatostatin (partially suppresses glucagon and insulin).
    • Pancreatic polypeptide (PP) acts as an inhibitor of digestion and absorption.
    • Hyperglycemic hormones raise blood glucose (glucagon, GH, epinephrine, norepinephrine, cortisol, corticosterone)
    • Hypoglycemic hormones lower blood glucose (insulin)

    Gonads

    • Ovaries and testes are both endocrine and exocrine organs.
    • Ovarian hormones: Estrogen, progesterone, and inhibin.
    • Testicular hormones: testosterone, androgens, estrogen, and inhibin.
    • Gonads promote development of reproductive systems and regulate cycles (e.g., menstrual, pregnancy).

    Other Tissues and Organs

    • Various tissues besides traditional endocrine glands produce hormones (e.g., skin, liver, kidneys, heart, stomach, small intestine, adipose tissue, osseous tissue, placenta).

    Hormone Chemistry

    • Hormones are broadly classified into three groups: steroids, monoamines, and peptides.

    Hormone Transport

    • Hydrophilic hormones (peptides, monoamines) mix easily with blood plasma.
    • Hydrophobic hormones (steroids, thyroid) bind to transport proteins, prolonging half-life in blood, protecting from breakdown, and ensuring only unbound hormones affect target cells.

    Hormone Receptors and Mode of Action

    • Target cells have specific receptors for hormones. Surface receptors for peptide and catecholamine hormones trigger intracellular second messenger systems; nuclear receptors for steroid and thyroid hormones affect gene expression.

    Signal Amplification

    • Hormone signals are potent; they can activate many enzyme molecules.

    Modulation of Target Cell Sensitivity

    • Receptor up-regulation increases sensitivity, receptor down-regulation reduces sensitivity.

    Hormone Interactions

    • Synergistic, permissive, and antagonistic interactions may occur between hormones affecting target cells.

    Hormone Clearance

    • Hormones are removed from the blood by the liver and kidneys to regulate blood levels.

    Stress and Adaptation (General Adaptation Syndrome)

    • Stress upsets homeostasis, triggering a response.
    • Alarm reaction: characterized by elevated epinephrine and norepinephrine.
    • Stage of resistance: dominated by cortisol to provide alternate fuels.
    • Stage of exhaustion: occurs with prolonged stress.

    Eicosanoids and Paracrine Signaling

    • Paracrine and autocrine signaling involves local messengers (eicosanoids, histamine, nitric oxide). -Eicosanoids, like prostaglandins, regulate various physiological processes.
    • NSAIDS inhibit eicosanoid synthesis.

    Endocrine Disorders

    • Hyposecretion and hypersecretion can result in various diseases (e.g., diabetes mellitus, pituitary, thyroid, parathyroid, adrenal disorders).

    Pituitary Disorders

    • Acromegaly (excess GH in adults), gigantism (excess GH in children), pituitary dwarfism (GH deficiency).

    Thyroid and Parathyroid Disorders

    • Hypothyroidism (low TH) and hyperthyroidism (high TH) manifest with different symptoms.
    • Goiter: enlargement of thyroid gland, often due to iodine deficiency.
    • Hypoparathyroidism and hyperparathyroidism cause imbalances in blood calcium.

    Adrenal Disorders

    • Cushing syndrome (excess cortisol), adrenogenital syndrome (excess adrenal androgens).

    Diabetes Mellitus

    • Caused by insufficient insulin or resistance to insulin. -Type 1 and type 2 are forms of the disease.
    • Pathogenesis, chronicity, and treatment vary for the two forms.

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Description

    Test your knowledge on the endocrine system with this quiz. Explore key concepts such as the differences between endocrine and exocrine glands, the role of hormones, and the interaction between the endocrine and nervous systems. Ideal for students studying health sciences or biology.

    More Like This

    Use Quizgecko on...
    Browser
    Browser